S2 - Pharmacy Medicine
Pharmacy medicine with restrictions
About S2 Drugs
Where S2 sits on the scale
A pharmacist can sell it directly, without a prescription.
Schedule 2 medicines sit behind the pharmacy counter. A pharmacist can decide to sell one of these directly, using their own professional judgement, without a doctor's prescription. It can also be dispensed against a prescription like the higher tiers, in which case the usual repeat limits apply. A child under 12 may only be sold a Schedule 2 substance on a prescription, or on a written order that names the purpose and carries a signature the seller recognises. Even though it cannot be advertised to the public in the ordinary sense, its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.
Cited: Act s22A(6)(e)
Who may supply
Only a pharmacist, pharmacist intern or supervised pharmacist's assistant may sell it without a prescription. It may otherwise be dispensed by a pharmacist against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.
Cited: Act s22A(5)(a), s22A(5)(d), s22A(5)(e), s22A(6)(r)
Repeats: If dispensed on prescription, it can be repeated only if the prescriber indicated a number of repeats, and never for more than six months in total; the prescription must also be presented for dispensing within 30 days of issue.
Cited: reg 33(3)(i) (General Regulations, 2017)
Cited: Act s22A(6)(d), s22A(6)(f)
Advertising: May be advertised only to health professionals, not the public.
Cited: reg 42(2), reg 42(3) (General Regulations, 2017)
Labelling: Must show the letter S and the number 2 in a square border, immediately before the product's brand name.
Cited: reg 10(1)(a) (General Regulations, 2017)
This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.
S2 Scheduled Drugs
| Name | Variants | Applicant | Number | Schedule |
|---|---|---|---|---|
| Carbocisteine (Acuphlem) | Not stated | Resmed healthcare | 270010 | S2 |
| Cimetidine (Secadine, Bio-cimetidine, Mexiena) | 200 mg, 400 mg, 200, 400 | Biotech Laboratories (Pty) Ltd | 5 registrations | S3 |
| Diclofenac (Panamor, A-lennon Diclofenac, Pharmflam, +11 more) | - 12,5, 75 mg, 25 mg, 50 mg, - 25, 50, - 75, injection/inspuiting, 25 mg/ml, - 100, 100 mg, gel, patch, 50.0 mg, 1 mg/ml, (dispersible tablet), 100, suppositories | Pharmacare limited û woodmead | 26 registrations | S3 |
| Carbocisteine (Mucoflem) | capsules | Viatris South Africa (Pty) Ltd | 270179 | S2 |
| Carbocisteine (Merck-carbocisteine) | syrup | Merck Generics Rsa (Pty) Ltd | 270180 | S2 |
| Cyclizine (Medazine S, Pinaloid) | 5 ml | Medpro Pharmaceutica (Pty) Ltd | 2 registrations | S2 |
| Carbocisteine (Mucoflem) | Not stated | Innovata pharmaceuticals | 270230 | S2 |
| Paracetamol, pseudoephedrine, triprolidine (Adco Flupain) | 1,5 g | Adcock ingram limited | 270260 | S2 |
| Mefenamic acid (Fenamin, Adco-mefenamic Acid, Ponstel Forte, +3 more) | 250 mg, 500 mg, 5 ml, 50 mg/5 ml, 250 | Adcock ingram limited | 9 registrations | S2 |
| Ibuprofen, paracetamol (Mypaid, Lotem, Mypaid Forte, +3 more) | 200mg / 250mg, 200 mg /250 mg, 200 mg and 250 mg, 400 mg/ 325 mg, tablets, suspension | Adcock ingram limited | 7 registrations | S3 |
| Carbocisteine (Dynaphlem, Mucodyne, Corbar M, +4 more) Cancelled | syrup | Adcock ingram limited | 7 registrations | S2 |
| Chlorpheniramine (Histabate) Cancelled | Not stated | Viatris Healthcare (Pty) Ltd | 270410 | S2 |
| Dextromethorphan, pseudoephedrine, triprolidine (Coryx Cough And Cold) | 5 mL/10 mg/30 mg/1.25 mg | Cipla Medpro (Pty) Ltd | 270490 | S2 |
| Codeine, guaifenesin, pseudoephedrine, triprolidine (Trifen Expect Paediatric, Trifen Expect Adult) | 5 mg/5 ml, 5 ml | Ranbaxy (SA) (Pty) Ltd | 2 registrations | S2 |
| Cinnarizine (Tranzet) Cancelled | Not stated | Medtrax Pharmaceuticals (Pty) Ltd | 270539 | S2 |
| Azelastine (Rhinolast Nasal) Cancelled | spray | Viatris Healthcare (Pty) Ltd | 270590 | S2 |
| Loperamide (Adco Loperamide, Gartromide, Adco Prodium, +3 more) | 2 mg, tablets | Adcock ingram limited | 6 registrations | S2 |
| Acetylcysteine (Solmucol, Tussmuco, Parvolex, +1 more) | 200, 400, 600 mg, 200mg / 10ml, 100 | Pharmacare limited û woodmead | 7 registrations | S2 |
| Loperamide (Dischem Anti-diarrhoeal, Lenide S, Gastron, +1 more) | tablets, -, syrup | Pharmacare limited û woodmead | 5 registrations | S2 |
| Carbocisteine (Betaphlem) | capsules | Unimed Healthcare (Pty) Ltd | 280232 | S2 |
| Ammonium chloride, codeine, diphenhydramine (Expectalin With Codeine, Benylin With Codeine) | 5 mL | Johnson & Johnson (Pty) Ltd û East London | 2 registrations | S2 |
| Carbocisteine (Mucoless, Mucoless S) | Not stated | Johnson & Johnson (Pty) Ltd û East London | 2 registrations | S2 |
| Diphenhydramine (Bennet's Diphenhydramine) Cancelled | elixir | Hersol Manufacturing Laboratories CC | 280483 | S2 |
| Loperamide (Loperastat) | 1 mg per 5 ml | Ranbaxy (SA) (Pty) Ltd | 280649 | S2 |
| Mepyramine (Antihist, Mepyraderm) | ampoules, cream | Unimed Healthcare (Pty) Ltd | 2 registrations | S2 |
| Vi capsular polysaccharide typhoid fever vaccine (Typhim Vi) | 0,5 mL | Sanofi-aventis South Africa (Pty) Ltd | 290091 | S2 |
| Carbocisteine (Flutex Mucous Cough, Mucospect, Bronchette, +4 more) | syrup, capsules | Pharmacare limited û woodmead | 8 registrations | S2 |
| Doxylamine (Repose, Somnil) | drops | Pharmacare limited û woodmead | 3 registrations | S2 |
| Loperamide (Imodium Melt, Imodium) | 2 mg | Johnson & Johnson (Pty) Ltd û East London | 3 registrations | S2 |
| Mebeverine (Bevispas) | Not stated | Pharmacare limited û woodmead | 290255 | S2 |
| Piroxicam (Rheugesic, Piroxicam Actor Dt) | 20 mg, 20, gel | Cipla Medpro (Pty) Ltd | 3 registrations | S2 |
| Ebastine (Kestine) | Not stated | Acs Pharmaceuticals (Pty) Ltd | 290344 | S2 |
| Bromhexine (Bronahex) Cancelled | solution | Pharmacare limited û woodmead | 290418 | S2 |
| Flavoxate (Urispas, Bladuril) | 200mg, 200 mg | Adcock ingram limited | 2 registrations | S2 |
| Mebeverine (Sandoz-mebeverine Hcl) Cancelled | 135 | Sandoz South Africa (Pty) Ltd | 290591 | S2 |
| Tetanus toxoid purified (Tetavax) Cancelled | Not stated | Sanofi-aventis South Africa (Pty) Ltd | 290637 | S2 |
| Caffeine, chlorpheniramine, ephedrine, paracetamol (Sinuend, Sinucon) | 200 mg/6 mg/ 20 mg/2 mg | Shanur Healthcare (Pty) Ltd | 2 registrations | S2 |
| Chlorpheniramine, paracetamol, pseudoephedrine, vitamin c (Flusin S, Endcol C, Flutex Fizzy, +3 more) | 50 mg/ 4 mg/ 500 mg/ 330 mg, effervescent | Pharmacare limited û woodmead | 6 registrations | S2 |
| Salbutamol (Airomir, Pholtex Chesty Cough, Duro-tuss, +1 more) | 4 mg. 2.41 mg/5 ml, 2.41 mg/5 ml | Inova Pharmaceuticals (Pty) Ltd | 4 registrations | S2 |
| Salbutamol (Asthavent, Asthavent Dp-caps, Asthavent Ecohaler, +4 more) | 2,0 mg/5 mL, 100 µg, 0,5 mg/2,5 mg in 2,5 mL, inhaler | Cipla Medpro (Pty) Ltd | 8 registrations | S3 |
| Codeine, ibuprofen, paracetamol (Mybulen, Mybucod, Ibumol Forte) | 10 mg/200 mg/350 mg, 200 mg/ 10 mg/ 250 mg | Pharmacare limited û woodmead | 5 registrations | S2 |
| Diclofenac (Flenodic Sr, Flenodic, Flenodic Im, +1 more) | 100, 25, 25 mg/ml, 75 mg | Biotech Laboratories (Pty) Ltd | 4 registrations | S3 |
| Albendazole (Zentel) | 400 mg, 20 mg/ml | Glaxosmithkline South Africa (Pty) Limited | 2 registrations | S2 |
| Ketotifen (Parke-med Ketotifen, Zetofen, Adco-ketotifen Alcohol And Sugar Free, +1 more) | drops | Adcock ingram limited | 4 registrations | S2 |
| Bromhexine, orciprenaline (Adco-linctopent) | 5 ml | Adcock ingram limited | 310011 | S2 |
| Pseudoephedrine, triprolidine (Betafed) | 5 ml | Ranbaxy Pharmaceutical (Pty) Ltd | 310249 | S2 |
| Nystatin (Candacide) | 100 000 iu per ml | Ranbaxy Pharmaceutical (Pty) Ltd | 310288 | S2 |
| Ibuprofen (Nurofen For Children Orange, Nurofen Express, Nurofen, +8 more) | 100 mg per 5 ml, 200 mg, caplets, gel capsules, gel, 200mg, 400mg, 200, powder, 400, tablets, 200 mg per 5 ml | Reckitt Benckinser Pharmaceuticals (Pty) Ltd | 16 registrations | S2 |
| Chlorpheniramine, paracetamol, pseudoephedrine (Sinumax Allergy Sinus) | 30 mg | Johnson & Johnson (Pty) Ltd û Cape Town | 310555 | S2 |
| Bromhexine (Dur-elix Mucolytic) | Not stated | Inova Pharmaceuticals (Pty) Ltd | 320232 | S2 |
| Mebeverine (Mylan Mebeverine) | Not stated | Viatris Healthcare (Pty) Ltd | 320598 | S2 |
| Mycobacterium bovis (Vesiculture) | 30 mg | Kahma Biotech (Pty) Ltd | 320745 | S2 |
| Antazoline, tetrahydrozoline (Ciballerge, Spersallerg Sdu (Single Dose Unit), Gemini, +1 more) | 1 ml, 0.5 mg /1 ml. | Adcock ingram limited | 4 registrations | S2 |
| Diphenhydramine, paracetamol, pseudoephedrine (Benylin Four Flu Liquid) | 20 mL | Johnson & Johnson (Pty) Ltd û East London | 330345 | S2 |
| Live attenuated measles virus (Priorix) | 0,5 ml | Glaxosmithkline South Africa (Pty) Limited | 330346 | S2 |
| Diphenhydramine, pseudoephedrine (Benylin Four Flu) | 12.5 mg/22.5 mg/500.0 mg | Johnson & Johnson (Pty) Ltd û East London | 330509 | S2 |
| Salbutamol (Venteze Easyhaler Forte, Venteze-eco, Venteze Cfc Free, +2 more) | 2 mg,4 mg, injection, inhaler, syrup, solution | Pharmacare limited û woodmead | 9 registrations | S2 |
| Paracetamol, pseudoephedrine (Sinugesic, Flusin Sinus) | 30 mg/ 500 mg, tablets | Pharmacare limited û woodmead | 2 registrations | S2 |
| Mupirocin (Bactroban, Bactroban Topical, Bactroban Nasal) | cream, 20mg, 2 g | Glaxosmithkline South Africa (Pty) Limited | 3 registrations | S2 |
| Caffeine, codeine, doxylamine, paracetamol (B-dol) | 10 mg | Unimed Healthcare (Pty) Ltd | 350065 | S2 |
| Desloratadine (Deselex, Neoclarityne) | tablets, syrup, 2,5 mg, 5 mg | Bayer (Pty) Ltd û Isando | 6 registrations | S2 |
| Trospium (Uricon) | 20mg | Viatris South Africa (Pty) Ltd | 350406 | S2 |
| Azelastine (Optilast) Cancelled | Not stated | Viatris South Africa (Pty) Ltd | 360011 | S2 |
| Chlorpheniramine (Rhineton) | 5 ml | Ranbaxy (SA) (Pty) Ltd | 2 registrations | S2 |
| Ibuprofen, pseudoephedrine (Benylin Daytime Flu, Sinutab 3-way) | 30 mg, 200 mg, 200 mg ,30 mg | Johnson & Johnson (Pty) Ltd û East London | 2 registrations | S2 |
| Loratadine (Rhineton Non Drowsy, Lorfast) | 10 mg | Ranbaxy (SA) (Pty) Ltd | 2 registrations | S2 |
| Doxylamine (Doxynite) | drops | Anmarate (Pty) Ltd | 360235 | S2 |
| Caffeine, codeine, doxylamine, paracetamol (Nomopain) | 450 mg, 5 mg, 30 mg, 10 mg | Lebasi Pharmaceuticals (Pty) Ltd | 360270 | S2 |
| Cetirizine (Allermine) | 10 mg | Trinity Pharma (Pty) Ltd | 360388 | S2 |
| Salbutamol (Ventimax Cfc Free, Ventimax Easi Breathe Cfc Free) | 100 μg | Biotech Laboratories (Pty) Ltd | 2 registrations | S2 |
| Omeprazole (Nozer, Gazigon, Gazigon Otc) | 20 mg | Dezzo Trading 392 (Pty) Ltd | 3 registrations | S4 |
| Levocetirizine (Xyzal) | 5mg & 0,5 mg/mL, oral solution | Glaxosmithkline South Africa (Pty) Limited | 2 registrations | S2 |
| Codeine, ibuprofen, paracetamol (Ibupain Forte) | 200 mg | Kiara Health (Pty) Ltd | 370060 | S2 |
| Atovaquone, proguanil (Malanil, Malanil Paediatric) | 250mg. 100mg | Acino Pharma (Pty) Ltd | 2 registrations | S2 |
| Ibuprofen, paracetamol (Ibugesic Plus) | 200 mg/ 250 mg | Cipla Medpro (Pty) Ltd | 370134 | S2 |
| Codeine, ibuprofen, paracetamol (Ibugesic Forte) | 200 mg. 250 mg. 10 mg | Cipla Medpro (Pty) Ltd | 370135 | S2 |
| Paracetamol, pseudoephedrine (Sinutab Sinus Pain Non Drowsy, Sudafed Sinus Pain) | 30 mg. 500 mg, 60 mg, 500 mg | Johnson & Johnson (Pty) Ltd û East London | 2 registrations | S2 |
| Chlorpheniramine, codeine, paracetamol, pseudoephedrine (Sinutab Sinus Pain Extra Strength) | 2 mg, 10 mg, 500 mg | Johnson & Johnson (Pty) Ltd û East London | 370139 | S2 |
| Codeine, paracetamol (Varipan Co) | 500 mg/8 mg | Lebasi Pharmaceuticals (Pty) Ltd | 370261 | S2 |
| Ibuprofen (Ibugesic Fever And Pain, Ibugesic) | 100 mg | Cipla Medpro (Pty) Ltd | 2 registrations | S2 |
| Cetirizine (Atrizin) | 10 mg | Ipharma (Pty) Ltd | 370497 | S2 |
| Chlorpheniramine, paracetamol, pseudoephedrine (Corenza Cold And Flu) | 5 ml | Adcock ingram limited | 370552 | S2 |
| Codeine, ibuprofen (Nurofen Plus) | 200 mg | Reckitt Benckinser Pharmaceuticals (Pty) Ltd | 370666 | S2 |
| Epinastine (Relestat) | 0.5mg | Abbvie (Pty) Ltd | 370691 | S2 |
| Actatense | 450 mg | Smart Pharmaceuticals (Pty) Ltd | 380152 | S2 |
| Dextromethorphan (Dilinct Dry Cough) | 15 mg | Adcock ingram limited | 380239 | S2 |
| Pantoprazole (Peptazol) | 40 mg, 20 mg | Pharmacorp (Pty) Ltd | 2 registrations | S4 |
| Desloratadine (Neoloridin, Arydese, Desotab) | 5, 2,5 | Zydus Healthcare (Pty) Ltd | 4 registrations | S2 |
| Colchicine (Aspen Colchicine Ds, Aspen Colchicine) | 1.0mg, 0,5 mg | Pharmacare limited û woodmead | 2 registrations | S2 |
| Human papillomavirus type, 1 protein (Cervarix) | 1 dose (0,5 mL) | Glaxosmithkline South Africa (Pty) Limited | 410366 | S2 |
| Desloratadine (Dazit, Deslotaz) | 5 mg, 2,5 mg | Ranbaxy Pharmaceutical (Pty) Ltd | 3 registrations | S2 |
| Desloratadine (Desodene, Desaway) | 5 mg. | Dr Reddyæs Laboratories (Pty) Ltd | 2 registrations | S2 |
| Pantoprazole (Pantocid, Conoran, Pantocid Otc) | 20, 40, 20mg | Ranbaxy Pharmaceutical (Pty) Ltd | 3 registrations | S4 |
| Pantoprazole (Aspen Pantoprazole Iv, Aspen Pantoprazole, Propintor Iv, +2 more) | 20 mg, 40 mg | Pharmacare limited û woodmead | 6 registrations | S2 |
| Desloratadine (Pollentyme Nd, Pollentyme Fc) | 5 mg | Astral Pharma (Pty) Ltd | 2 registrations | S2 |
| Desloratadine (Clarex) | 5 | Unicorn Pharmaceuticals (Pty) Ltd | 420985 | S2 |
| Desloratadine (Deslomed, Demiltix) | 2.5 mg, 5 ml | Adcock ingram limited | 2 registrations | S2 |
| Rotarix Liquid Vaccine | 1,5 ml | Glaxosmithkline South Africa (Pty) Limited | 430290 | S2 |
| Non-typeable haemophilus influenzae nthi protein (Synflorix) | 0,5 mL | Glaxosmithkline South Africa (Pty) Limited | 430401 | S2 |
| Flunarizine (Sibelium T, Sibelium) Cancelled | 5 mg, 10 mg | Janssen Pharmaceutica (Pty) Ltd | 2 registrations | S2 |
| Filamentous haemagglutinin, pertactin, pertussis toxoid (Boostrix Tetra) | 0,5 mL | Glaxosmithkline South Africa (Pty) Limited | 430526 | S2 |
| Measles virus vaccine live attenuated (Measbio) | 0,5 ml | The biovac institute | 430541 | S2 |
| Cetirizine (AURO Cetirizine, Trantrin) | 5 mg, 10 mg | Aurogen South Africa (Pty) Ltd | 4 registrations | S2 |
| Pantoprazole (Mylan-pantoprazole, Prazgen Otc, Panzolym Otc) | 20 mg, 40 mg | Viatris South Africa (Pty) Ltd | 4 registrations | S2 |
| Pantoprazole (Prazoloc Otc, Medpro Pantoprazole, Prazoloc, +4 more) | 20 mg, 40, 20, 40 mg | Cipla Medpro (Pty) Ltd | 9 registrations | S2 |
| Desloratadine (Cipla Desloratadine, Loralex) Cancelled | Not stated | Cipla Medpro (Pty) Ltd | 2 registrations | S2 |
| Esomeprazole (Nexipraz Otc, Nexipraz, Nexipraz Iv) | 30 mg, 20, 40, 40 mg | Ranbaxy Pharmaceutical (Pty) Ltd | 4 registrations | S4 |
| Desloratadine (Acuhist) Cancelled | 5 mg | Teva Pharmaceuticals (Pty) Ltd | 450795 | S2 |
| Desloratadine (Dehrin) | 2,5 mg | Abex Pharmaceutica (Pty) Ltd | 460004 | S2 |
| Dicyclomine, aluminium hydroxide, light magnesium oxide (Meddev) | 10 ml | Medicine Developers International (Pty) Ltd | 460086 | S2 |
| Ammonium chloride, diphenhydramine (Diphal Expectorant) | 5 ml | Medicine Developers International (Pty) Ltd | 460087 | S2 |
| Azelastine (Arzep Nasal, Azelastine Zydus) | spray, 0,14 mg | Zydus Healthcare (Pty) Ltd | 2 registrations | S2 |
| Rupatadine (Rupanase, Rupallerg) | 10 | Inova Pharmaceuticals (Pty) Ltd | 2 registrations | S2 |
| Levocetirizine (Levizal, Xyleve, Xyleve Odt, +2 more) | 5 mg, solution, 0,5 mg | Trinity Pharma (Pty) Ltd | 5 registrations | S2 |
| Ulipristal (Ella) | 30 mg | Cipla Medpro (Pty) Ltd | 460280 | S2 |
| Levocetirizine (Cetaway) | 0.5mg/ml | Unicorn Pharmaceuticals (Pty) Ltd | 460389 | S2 |
| Desloratadine (Austell Desloratadine) Cancelled | 5 mg | Camox Pharmaceuticals (Pty) Ltd | 460492 | S2 |
| Desloratadine (Aerzit) | 5 | Austell Pharmaceuticals (Pty) Ltd | 460493 | S2 |
| Desloratadine (Desloratadine Unimed) | 5 | Unimed Healthcare (Pty) Ltd | 460503 | S2 |
| Esomeprazole (Nexilok) | 20mg, 0,6 mg | Teva Pharmaceuticals (Pty) Ltd | 2 registrations | S2 |
| Desloratadine (Deseneeze) | 2,5 mg/5 ml | Pharmacare limited û woodmead | 460697 | S2 |
| Xylometazoline, ipratropium (Otrivin Plus) | 0.5 mg/ml + 0.6 mg/m | Glaxosmithkline Consumer Healthcare SA (Pty) Ltd | 460819 | S2 |
| Azelastine (Azelastine Pharma-q) | Not stated | Pharma-q Holdings (Pty) Ltd | 470142 | S2 |
| Ketotifen (Ketagex Eye) | drops | Soflens (Pty) Ltd | 471166 | S2 |
| Paracetamol (Paraconica Iv, Paramed, Empaped) | tablets, 125 mg, 250 | Acino Pharma (Pty) Ltd | 4 registrations | S2 |
| Esomeprazole (Merpax Iv, Nextell Otc, Esomeprazole Austell) | 20 mg, 40 mg | Austell Pharmaceuticals (Pty) Ltd | 3 registrations | S2 |
| Ebastine (Noribas) | 10 MG | Pharma-q Holdings (Pty) Ltd | 480921 | S2 |
| Cetirizine (Allesoothe) | 10 mg | Forrester Pharma (Pty) Ltd | 481197 | S2 |
| Flavoxate (Flospasm) | 200 mg | Pharmacare limited û woodmead | 490064 | S2 |
| Salbutamol (Azmaler) | 100 μg | Unimed Healthcare (Pty) Ltd | 490135 | S2 |
| Tetanus toxoid (Tetanus Vaccine Cipla) | Not stated | Cipla Medpro (Pty) Ltd | 490162 | S2 |
| Diphtheria toxoid nlt, filamentous haemagglutinin, pertactin, pertussis toxoid, tetanus toxoid nlt (Boostrix) | 0,5 ml | Glaxosmithkline South Africa (Pty) Limited | 491042 | S2 |
| Desloratadine (Neoscend, Neoscend Odt, Lornid, +1 more) | 5, 2,5 | Ascendis Pharma (Pty) Ltd | 5 registrations | S2 |
| Paracetamol (Pyracet) | 125, 250 | Activo Health (Pty) Ltd | 2 registrations | S2 |
| Colchicine (Kolcrys) | 0,5 mg | Forrester Pharma (Pty) Ltd | 500484 | S2 |
| Paracetamol, ibuprofen, condeine (Mybulen Forte) | 400 mg/10 mg/500 mg | Pharmacare limited û woodmead | 500490 | S2 |
| Colchicine (Goutcha, Gouteze Otc, Colcin) | 0,5 mg | Abex Pharmaceutica (Pty) Ltd | 3 registrations | S2 |
| Available iodine (Betadine Vaginal) | 10 % w/w | Inova Pharmaceuticals (Pty) Ltd | 510531 | S2 |
| Otilonium (Spasmomen) | 40 mg | Menarini South Africa (Pty) Ltd | 510623 | S2 |
| Diphtheria toxoid 2 0 lf, filamentous haemagglutinin, fimbriae 2, pertactin, pertussis toxoid (Adacel) | 0,5 ml | Sanofi-aventis South Africa (Pty) Ltd | 510837 | S2 |
| Influenza virus vaccine a a b b (Vaxigrip Tetra) | Not stated | Sanofi-aventis South Africa (Pty) Ltd | 510838 | S2 |
| Influenza virus vaccine (Influvac Tetra) | 0,5 mL | Abbott Laboratories S.A. (Pty) Ltd | 520094 | S2 |
| Bilastine (Ilaxten, Ilaxten Odt) | 20 mg, 2,5 mg/ml, 10 mg | Menarini South Africa (Pty) Ltd | 3 registrations | S2 |
| Rupatadine (Rutarn) | 10 | Austell Pharmaceuticals (Pty) Ltd | 520184 | S2 |
| Tetanus toxoid (Tetanus Toxoid Biovac) | Not stated | The biovac institute | 520244 | S2 |
| Mupirocin (Muprican) | 20 mg | Abex Pharmaceutica (Pty) Ltd | 520254 | S2 |
| Mupirocin (Piban) | 20 mg | Macleods Pharmaceuticals SA (Pty) Ltd | 520255.254 | S2 |
| Potassium chloride (Plenish-k Sr, Plenish K, Micro-k Extencaps) | 600 mg, - | Pharmacare limited û woodmead | 3 registrations | S2 |
| Salbutamol (Proventil) | 100 µg | Ipharma (Pty) Ltd | 520726 | S2 |
| Ebastine (Ebastine Adco, Allerbas Allergy) Cancelled | 10 mg | Adcock ingram limited | 2 registrations | S2 |
| Olopatadine (Oftapat) | 1,0 mg | Austell Pharmaceuticals (Pty) Ltd | 530401 | S2 |
| Fosfomycin (Uticide) | 3 g | Unicorn Pharmaceuticals (Pty) Ltd | 530574 | S2 |
| Levonorgestrel (Levonorgestrel Unicorn) | 1,5 mg | Unicorn Pharmaceuticals (Pty) Ltd | 530608 | S2 |
| Rupatadine (Rupagex, Rupaxine) | 10 mg | Adcock ingram limited | 2 registrations | S2 |
| Paracetamol, ibuprofen (Parafengen Iv, *Empaped Plus) | 1000 mg, 300 mg, 5 ml | Acino Pharma (Pty) Ltd | 2 registrations | S3 |
| Doxylamine (Nomowake) | 25 mg | Lebasi Pharmaceuticals (Pty) Ltd | 540168 | S2 |
| Ketotifen (Ketotifen Ipharma) | 0,25 mg | Ipharma (Pty) Ltd | 540176 | S2 |
| Acetylsalicylic acid (Cardasa) | 100 mg | Viatris Healthcare (Pty) Ltd | 540456 | S2 |
| Rupatadine (Zealargy) | 10 mg | Pharma-q Holdings (Pty) Ltd | 540789 | S2 |
| Colchicine (Cinwol, Choldix, Cinited) | 0,5 mg | Aurogen South Africa (Pty) Ltd | 3 registrations | S2 |
| Rupatadine (Raztrol) | 10mg | Ranbaxy (SA) (Pty) Ltd | 550293 | S2 |
| Abiraterone (Alernova) | 0,5 mg | Trinity Pharma (Pty) Ltd | 550310.309 | S2 |
| Colchicine (Uricid) | 0.5 mg | Trinity Pharma (Pty) Ltd | 550337.336 | S2 |
| Lactobacillus acidophilus 1 10 cfu estriol (Gynoflor) | 1x108 CFU, 0,03 mg | Adcock ingram limited | 550343 | S2 |
| Azelastine, fluticasone propionate (Dymista Nasal) | 1,0 mg and 0,365 mg | Viatris Healthcare (Pty) Ltd | 550573 | S2 |
| Methocarbamol (Mylospas) | 750 mg | Austell Pharmaceuticals (Pty) Ltd | 550765 | S2 |
| Methocarbamol (Methocarbamol Shanur) | 750 mg | Shanur Healthcare (Pty) Ltd | 550766 | S2 |
| Cyproheptadine (Zyactin, Cyproheptadine Zydus) | 4 mg | Zydus Healthcare (Pty) Ltd | 2 registrations | S2 |
| Ibuprofen, pseudoephedrine (Declozit) | 200 mg/30 mg | Pharmacare limited û woodmead | 560390 | S2 |
| Desloratadine (Deraliqe) | Not stated | Pharmacorp (Pty) Ltd | 560532 | S2 |
| Diclofenac (Diclofenac Unicorn) | 50 mg | Unicorn Pharmaceuticals (Pty) Ltd | 560559 | S2 |
| Diphenhydramine, codeine, ammonium chloride (Benylin Forte) | 12.5 mg, 10 mg, 125 mg | Johnson & Johnson (Pty) Ltd û Cape Town | 560570 | S2 |
| Bilastine (Basmedene, Basmedene Odt) | 20, 10 | Trinity Pharma (Pty) Ltd | 2 registrations | S2 |
| Ameprazole (Tumsigon Otc) | 20 mg | Dezzo Trading 392 (Pty) Ltd | 560847 | S2 |
| Levonorgestrel (Lornestin, Trinestin) | 1,50 mg | Trinity Pharma (Pty) Ltd | 2 registrations | S2 |
| Cholestyramine resin (Tyrachol) | powder | Ascend Laboratories (Pty) Ltd | 561213 | S2 |
| Sars-cov-2rs recombinant spike protein (Covovax) | 5,0 μg | Cipla Medpro (Pty) Ltd | 561236 | S2 |
| Cyproheptadine (Actincypro) | 4 mg | Pharmacare limited û woodmead | 570019 | S2 |
| Rupatadine (Raputeze, Histanaze) | 10 mg | Abex Pharmaceutica (Pty) Ltd | 2 registrations | S2 |
| Desloratadine (Avarinex) | 2.5 mg | Innovata pharmaceuticals | 570168 | S2 |
| Rupatadine (Rupastral) | 10 mg | Astral Pharma (Pty) Ltd | 570199 | S2 |
| Rupatadine (Rupahist) | Not stated | Unimed Healthcare (Pty) Ltd | 580062 | S2 |
| Diphtheria toxoid, tetanus toxoid, bordetella pertussis, hepatitis b surface antigen, inactivated polio vaccine type i 40 0 du type 2 8 0 du type 3 32 0 du haemophilus influenzae type b, conjugate to tetanus toxoid 19 0 to (Cihexa) | ≥ 30 IU, ≥ 40 IU, ≥ 4 IU, 15 mcg, 40 DU, 8 DU, 32 DU, 10 mcg | Cipla Medpro (Pty) Ltd | 590479 | S2 |
| Pneumococcal polysaccharide conjugate vaccine (Prevenar) | 20 mg | Pfizer Laboratories (Pty) Ltd | 590853 | S2 |
| Albendazole (Albendazole Cospharm) | 1 mg | Cospharm Investments (Pty) Ltd | 610846 | S2 |
| Bromhexine (Bisolvon Vet, Bisolvon) | Not stated | Janssen Pharmaceutica (Pty) Ltd | 2 registrations | S2 |
| Sumatriptan (Migrex Otc, Migrex) | 50 mg | Sandoz South Africa (Pty) Ltd | 2 registrations | S2 |
| Loperamide (Loperim, Dilorax) | Not stated | Mothopo pharma chem | 2 registrations | S2 |
| Loperamide (Lopidium, Cipla Loperamide) | Not stated | Cipla Medpro (Pty) Ltd | 2 registrations | S2 |
| Chlorpheniramine, paracetamol, vitamin c (Efferflu-c Cold & Flu) | 250 mg | Pharma Dynamics (Pty) Ltd | A390451 | S2 |
| Chlorpheniramine (Allerchlor) | 4 mg | Pharmacare limited û woodmead | A400375 | S2 |
| Proglumide (Milid) Cancelled | Not stated | Scp Pharmaceuticals (Pty) Ltd | B0143 | S2 |
| Prifinium (Riabal) Cancelled | injection | The Premier Pharmaceutical Co Ltd | 2 registrations | S2 |
| Pipoxolan (Rowapraxin) Cancelled | Not stated | Adcock ingram limited | B0178 | S2 |
| Chlorzoxazone (Paraflex) | Not stated | Janssen Pharmaceutica (Pty) Ltd | B1018 | S2 |
| Mephenesin, paracetamol (Spasmend) | 150 mg, 500 mg | Adcock ingram limited | B1490 | S2 |
| Methocarbamol (Robaxin) | tablets | Glaxosmithkline Consumer Healthcare SA (Pty) Ltd | B1554 | S2 |
| Methocarbamol (Robaxin) | 750 | Haleon South Africa (Pty) Ltd | B1555 | S2 |
| Povidone-iodine (Betadine Mouthwash & Gargle, Betadine Douche, Betadine Vaginal, +3 more) Cancelled | 10 % w/w, solution, 7,5 % w/v, 100 mg / 1 g | Mundipharma (Pty) Ltd | 7 registrations | S2 |
| Chlorpheniramine, phenylephrine (Demazin) | 1,25 mg and 2,5 mg, | Inova Pharmaceuticals (Pty) Ltd | C0535 | S2 |