Adrenaline
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
Drag to rotate. Structure from PubChem CID 5816.
Background
Listing
- Schedules
- Schedule 2 to 4, conditions apply
- Also listed as
- Epinephrine (Schedule 4)
- Source
- Consolidated Schedules 06 July 2026
Registered medicines
9 registered products listed
Counted through the register's ingredient index, which does not reach every record.
| Name | Brands | Dosages | Applicants | Registrations | Schedule |
|---|---|---|---|---|---|
| Adrenaline | Epipen, Epipen junior auto-injector, Ana-guard | 0.15mg / 0.3ml, 0.3mg / 0.3ml | 2 applicants | 3 registrations | S4 |
| Epinephrine | Adrenotone | ampoules | Viatris Healthcare (Pty) Ltd | 290025 | S2 to S4conditions apply |
| Epinephrine bitartrate | Pharma-q adrenaline, Episup junior auto-injector, Adrenoject, +3 more | 1 mg/ml, 1 mg/1 ml, 200 | 6 applicants | 6 registrations | S2 to S4conditions apply |
| Adrenaline, articaine Cancelled | Ubistesin, Ubistesin forte | Not stated | 3m South Africa (Pty) Ltd | 2 registrations | S2 to S4conditions apply |
| Epinephrine, mepivacaine | Carbocaine a 1:100, Carbocaine a 1:200 | 2% 000 | Adcock ingram limited | 2 registrations | S2 to S4conditions apply |
| Epinephrine bitartrate, lidocaine | Lignotox "a", Lignane a, Lidocaine a | 80 | 3 applicants | 3 registrations | S1 to S4conditions apply |
| Epinephrine, lidocaine | Lignospan | 2% | The Dental Warehouse (Pty) Ltd | J0208 | S1 to S4conditions apply |
| Adrenaline, lidocaine | Xylotox e80-a, Xylestesin-a, Locaine a | Not stated | 2 applicants | 3 registrations | S1 to S4conditions apply |
| Adrenaline, mepivacaine | Scandonest special | 2 % | The Dental Warehouse (Pty) Ltd | Y0421 | S2 to S4conditions apply |
Regulatory status
Where S2 to S4 sits on the scale
Depends on which listing applies
At the least restrictive, Schedule 2: a pharmacist can sell it directly, without a prescription. At the most restrictive, Schedule 4: prescription-only medicine. The listings below say which applies to which form, strength or pack size.
Schedule S2 to S4, as the Consolidated Schedules list it.
Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.
Consolidated Schedules listings for Adrenaline
S4: Adrenaline
- when intended for injection.
Consolidated Schedules 06 July 2026, line 5148
S3: Adrenaline (epinephrine)
- ophthalmic preparations thereof, when intended for glaucoma.
Consolidated Schedules 06 July 2026, line 3122
S2: Adrenaline (epinephrine)
- except ophthalmic preparations when intended for glaucoma, and
- except preparations for injection. (S3, S4)
Consolidated Schedules 06 July 2026, lines 1561 to 1565
This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.