Chlorpheniramine
Sold as Histabate, Rhineton, Allerchlor, Nutrahist, Allergex, Allergex retard, Chlorpheniramine maleate, Histamed elixer, Chlorhist, Allerhist, Chlorcol eye
3-(4-Chlorophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine
Drag to rotate. Structure from PubChem CID 2725.
Background
Registration
- Applicants
- 6
- Registrations
- 14
- Schedule source
- Consolidated Schedules 06 July 2026
Applicants and registrations
| Applicant | Brands | Dosages | Registrations | Schedule | Leaflets |
|---|---|---|---|---|---|
| Viatris Healthcare (Pty) LtdCancelled | Histabate | Not stated | 270410 | S2 | None |
| Ranbaxy (SA) (Pty) LtdCertificate held by Ranbaxy Pharmaceuticals (Pty) Ltd. | Rhineton | 5 ml | 360166, 410780 | S2 | PIPIL |
| Pharmacare limited û woodmead | Allerchlor | 4 mg | A400375 | S2 | None |
| The Premier Pharmaceutical Co LtdCancelled | Nutrahist, Allergex retard, Histamed elixer, Chlorhist | syrup, capsules | C0656, C0669, C0762, C0995 | S2 | None |
| Adcock ingram limited3 of 5 cancelled | Allergex, Chlorhist, Allerhist, Chlorcol eye | 4 mg, syrup, capsules, elixir, ointment | C0668, C0789, C0792, C0807, H1301 | S2 | PIPIL |
| Alex Lipworth LtdCancelled | Chlorpheniramine maleate | tablets | C0733 | S2 | None |
Variants
| Product | Strength and form | Registration | Status | Schedule | Leaflets |
|---|---|---|---|---|---|
| Histabate EACH TABLET CONTAINS CHLORPHENIRAMINE MALEATE 10 mg | Not listed | 27041027/5.7.1/0410 | Cancelled | S2 | None |
| Rhineton EACH TABLET CONTAINS CHLORPHENIRAMINE MALEATE 4,0 mg | Not listed | 36016636/5.7.1/0166 | Registered | S2 | None |
| Rhineton syrup EACH 5,0 ml SYRUP CONTAINS CHLORPHENIRAMINE MALEATE 2,0 mg | 5 mlSyrup | 41078041/5.7.1/0780Approved 10 November 2022 | Registered | S2 | PIPIL |
| Allerchlor 4 MG EACH TABLET CONTAINS CHLORPHENIRAMINE MALEATE 4,0 mg | 4 mg | A400375A40/5.7.1/0375 | Registered | S2 | None |
| Nutrahist syrup TABLET CHLORPHENIRAMINE MALEATE A 2 MG | Syrup | C0656 | Cancelled | S2 | None |
| Allergex tablets EACH TABLET CONTAINS :CHLORPHENIRAMINE MALEATE A 4,0 mg | 4 mgTablets | C0668Approved 8 March 2024 | Old Medicine | S2 | PIPIL |
| Allergex retard TABLET CHLORPHENIRAMINE MALEATE A 8 MG | Not listed | C0669 | Cancelled | S2 | None |
| Chlorpheniramine maleate tablets TABLET CHLORPHENIRAMINE MALEATE A 4 MG | Tablets | C0733 | Cancelled | S2 | None |
| Histamed elixer 5 ML CHLORPHENIRAMINE MALEATE A 2 MG | Not listed | C0762 | Cancelled | S2 | None |
| Chlorhist syrup 5 ML CHLORPHENIRAMINE MALEATE A 2 MG | Syrup | C0789 | Cancelled | S2 | None |
| Allerhist capsules EACH CAPSULE CONTAINS CHLORPHENIRAMINE MALEATE A 4 mg | Capsules | C0792 | Cancelled | S2 | None |
| Allergex elixir EACH 5,0 ml LIQUID CONTAINS :CHLORPHENIRAMINE MALEATE A 2,0 mg | Elixir | C0807 | Old Medicine | S2 | None |
| Chlorhist capsules CAPSULE CHLORPHENIRAMINE MALEATE A 12 MG | Capsules | C0995 | Cancelled | S2 | None |
| Chlorcol eye ointment EACH GRAM CONTAINS CHLORPHENIRAMINE MALEATE A 10 mg | Ointment | H1301 | Cancelled | S2 | None |
Regulatory status
Where S2 sits on the scale
A pharmacist can sell it directly, without a prescription.
Schedule 2 medicines sit behind the pharmacy counter. A pharmacist can decide to sell one of these directly, using their own professional judgement, without a doctor's prescription. It can also be dispensed against a prescription like the higher tiers, in which case the usual repeat limits apply. A child under 12 may only be sold a Schedule 2 substance on a prescription, or on a written order that names the purpose and carries a signature the seller recognises. Even though it cannot be advertised to the public in the ordinary sense, its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.
Schedule S2, matched to the Consolidated Schedules by ingredient, confidence high.
Who may supply: Only a pharmacist, pharmacist intern or supervised pharmacist's assistant may sell it without a prescription. It may otherwise be dispensed by a pharmacist against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.
Consolidated Schedules listings for Chlorpheniramine maleate
S2: Chlorpheniramine
Consolidated Schedules 06 July 2026, line 1732
Pharmacological class: Antihistaminics. (class 5.7.1)
This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.
SAHPRA documents
Schedule Verification
Rhineton syrup, Ranbaxy (SA) (Pty) Ltd is scheduled S2 in its official SAHPRA documents, read with 90% confidence.
These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.