Cetirizine

Sold as Zetop, Sinutab sinus allergy, Verlix, Texa allergy, Adco cetirizine, Ceticit, Allermine, Allecet, Acuzyrt, Seasoneze, Zelary, Aspen cetirizine, Atrizin, Austell cetirizine, Cetirizine austell, Zyncet, Reactyne, Gulf cetirizine, Sensahist, Cetirizine shanur, Zinallerg, AURO cetirizine, Trantrin, Allesoothe, Zialdel, Derasip, Cetriliqe, Cetirizine unimed, Zyrtec

S2Read from the PI-PIL document and verified

C₂₁H₂₅ClN₂O₃388.90 g/mol

2-[2-[4-[(4-Chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid

Drag to rotate. Structure from PubChem CID 2678.

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Registration

Applicants: 23
Registrations: 42
Schedule source: SAHPRA documentation

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Pharma-q Holdings (Pty) Ltd	Zetop	Not stated	320374	Not determined	None
Ascendis Pharma (Pty) Ltd	Zetop	syrup	330030	Not determined	None
Johnson & Johnson (Pty) Ltd û East London1 of 4 cancelled	Sinutab sinus allergy, Reactyne	solution, effervescent	350296, 350298, 410420, 410426	Not determined	None
Ucb SA (Pty) LtdCancelled	Verlix	10 mg/ML	350297	Not determined	None
Pharma Dynamics (Pty) Ltd	Texa allergy	tablets, syrup	350314, 410086	Not determined	None
Adcock ingram limited1 of 3 cancelled	Adco cetirizine, Ceticit	tablets, 1 mg/1 mL, 10mg	360368, 360369, 420821	Not determined	PI PIL
Trinity Pharma (Pty) Ltd	Allermine	10 mg	360388	S2	PI PIL
Cipla Medpro (Pty) LtdCertificate held by Cipla Medpro (Pty) Ltd.1 of 4 cancelled	Allecet, Acuzyrt	10,0 mg, tablets, 1 mL	370034, 370072, 370152, 370153	S1	PI PIL
Biotech Laboratories (Pty) Ltd	Seasoneze	10 mg	370086	S1	PI PIL
Austell Pharmaceuticals (Pty) LtdCertificate held by Austell Pharmaceuticals (Pty) Ltd,	Zelary, Austell cetirizine, Cetirizine austell	5 mg, 10 mg	370428, 370579, 370579, 370580	S1	PI PIL
Pharmacare limited û woodmeadCancelled	Aspen cetirizine	1 mg/ml, 10 mg	370490, 420143	Not determined	None
Ipharma (Pty) Ltd	Atrizin	10 mg	370497	S2	PI PIL
Unichem SA (Pty) Ltd	Zyncet	10 mg	370651	S1	PI PIL
Unicorn Pharmaceuticals (Pty) Ltd	Zelary	syrup	410085	Not determined	None
Gulf Drug Company (Pty) Ltd	Gulf cetirizine	10	410555	Not determined	None
Oethmaan Biosims (Pty) Ltd	Sensahist, Zinallerg	Not stated	420822, 430359	Not determined	None
Shanur Healthcare (Pty) Ltd	Cetirizine shanur	10	430358	Not determined	None
Aurogen South Africa (Pty) LtdCertificate held by Aurogen Southafrica (Pty) Ltd	AURO cetirizine, Trantrin	5 mg, 10 mg	430643, 430644, 430645, 430646	S2	PI PIL
Forrester Pharma (Pty) Ltd	Allesoothe	10 mg	481197	S2	PI PIL
Hetero Drugs South Africa (Pty) Ltd	Zialdel, Derasip	5 mg/5 ml	530404, 530405.404	Not determined	None
Pharmacorp (Pty) Ltd	Cetriliqe	Not stated	580260	Not determined	None
Unimed Healthcare (Pty) Ltd	Cetirizine unimed	oral solution, 10	A390103, A390384	Not determined	None
Glaxosmithkline South Africa (Pty) Limited	Zyrtec	10 mg	W0148	Not determined	None

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Zetop EACH TABLET CONTAINS CETIRIZINE DIHYDROCHLORIDE 10,0 mg	Not listed	32037432/5.7.1/0374	Registered	Not determined	None
Zetop syrup EACH 1,0 ml SYRUP CONTAINS CETIRIZINE DIHYDROCHLORIDE 1,0 mg	Syrup	33003033/5.7.1/0030	Registered	Not determined	None
Sinutab sinus allergy EACH TABLET CONTAINS CETIRIZINE DIHYDROCHLORIDE 10,0 mg	Not listed	35029635/5.7.1/0296	Registered	Not determined	None
Verlix oral drops 10 mg/ml EACH 1,0 ml SOLUTION CONTAINS CETIRIZINE DIHYDROCHLORIDE 10,0 mg	10 mg/MLOral drops	35029735/5.7.1/0297	Cancelled	Not determined	None
Sinutab sinus allergy solution EACH 1,0 ml SOLUTION CONTAINS CETIRIZINE DIHYDROCHLORIDE 1,0 mg	Solution	35029835/5.7.1/0298	Registered	Not determined	None
Texa allergy tablets EACH TABLET CONTAINS CETIRIZINE HYDROCHLORIDE 10,0 mg	Tablets	35031435/5.7.1/0314	Registered	Not determined	None
Adco cetirizine tablets EACH TABLET CONTAINS CETIRIZINE DIHYDROCHLORIDE 10,0 mg	Tablets	36036836/5.7.1/0368	Cancelled	Not determined	None
Ceticit syrup EACH 1,0 ml SYRUP CONTAINS CETIRIZINE DIHYDROCHLORIDE 1,0 mg	1 mg/1 mLOral syrup	36036936/5.7.1/0369Approved 20 February 2024	Registered	Not determined	PI PIL
Allermine tablets EACH TABLET CONTAINS CETIRIZINE DIHYDROCHLORIDE 10,0 mg	10 mgTablet	36038836/5.7.1/0388Approved 14 August 2025	Registered	S2	PI PIL
Allecet EACH TABLET CONTAINS CETIRIZINE DIHYDROCHLORIDE 10,0 mg	10,0 mgFilm-coated tablets	37003437/5.7.1/0034Approved 28 October 2024	Registered	S1	PI PIL
Acuzyrt tablets EACH TABLET CONTAINS CETIRIZINE DIHYDROCHLORIDE 10,0 mg	Tablets	37007237/5.7.1/0072	Cancelled	Not determined	None
Seasoneze EACH TABLET CONTAINS CETIRIZINE DIHYDROCHLORIDE 10,0 mg	10 mgFilm-coated tablets.	37008637/5.7.1/0086Approved 19 February 2025	Registered	S1	PI PIL
Acuzyrt syrup EACH 5,0 ml SYRUP CONTAINS CETIRIZINE DIHYDROCHLORIDE 5,0 mg	1 mLSyrup	37015237/5.7.1/0152Approved 28 February 2024	Registered	S1	PI PIL
Allecet syrup EACH 5,0 ml SYRUP CONTAINS CETIRIZINE DIHYDROCHLORIDE 5,0 mg	1 mLSyrup	37015337/5.7.1/0153Approved 28 February 2024	Registered	S1	PI PIL
Zelary 10 EACH TABLET CONTAINS CETIRIZINE DIHYDROCHLORIDE 10,0 mg	10 mgFilm-coated tablets	37042837/5.7.1/0428Approved 18 October 2024	Registered	S1	PI PIL
Aspen cetirizine 10 MG EACH TABLET CONTAINS CETIRIZINE DIHYDROCHLORIDE 10,0 mg	10 mg	37049037/5.7.1/0490	Cancelled	Not determined	None
Atrizin 10 EACH TABLET CONTAINS CETIRIZINE DIHYDROCHLORIDE 10,0 mg	10 mgTablets	37049737/5.7.1/0497Approved 3 February 2021	Registered	S2	PI PIL
Austell cetirizine 5 MG EACH TABLET CONTAINS CETIRIZINE DIHYDROCHLORIDE 5,0 mg	5 mg	37057937/5.7.1/0579	Registered	Not determined	None
Cetirizine 5 MG austell EACH TABLET CONTAINS: CETIRIZINE DIHYDROCHLORIDE 5,0 mg	5 mg	37057937/5.7.1/0579	Registered	Not determined	None
Austell cetirizine 10 MG EACH TABLET CONTAINS :CETIRIZINE DIHYDROCHLORIDE 10,0 mg	10 mg	37058037/5.7.1/0580	Registered	Not determined	None
Zyncet EACH TABLET CONTAINS CETIRIZINE DIHYDROCHLORIDE 10,0 mg	10 mgFilm-coated tablets	37065137/5.7.1/0651Approved 31 May 2024	Registered	S1	PI PIL
Zelary syrup EACH 1,0 ml SYRUP CONTAINS CETIRIZINE DIHYDROCHLORIDE 1,0 mg	Syrup	41008541/7.5.1/0085	Registered	Not determined	None
Texa allergy syrup EACH 1,0 ml SYRUP CONTAINS CETIRIZINE DIHYDROCHLORIDE 1,0 mg	Syrup	41008641/5.7.1/0086	Registered	Not determined	None
Sinutab sinus allergy effervescent EACH EFFERVESCENT TABLET CONTAINS CETIRIZINE DIHYDROCHLORIDE 10,0 mg	Effervescent	41042041/5.7.1/0420	Registered	Not determined	None
Reactyne effervescent EACH EFFERVESCENT TABLET CONTAINS CETIRIZINE DIHYDROCHLORIDE 10,0 mg	Effervescent	41042641/5.7.1/0426	Cancelled	Not determined	None
Gulf cetirizine 10 EACH TABLET CONTAINS CETIRIZINE DIHYDROCHLORIDE 10,0 mg	10	41055541/5.7.1/0555	Registered	Not determined	None
Aspen cetirizine 1 mg/ml EACH 1,0 ml SOLUTION CONTAINS CETIRIZINE DIHYDROCHLORIDE 1,0 mg	1 mg/ml	42014342/5.7.1/0143	Cancelled	Not determined	None
Ceticit EACH TABLET CONTAINS CETIRIZINE DIHYDROCHLORIDE 10,0 mg	10mgFilm-coated tablets	42082142/5.7.1/0821Approved 20 February 2024	Registered	Not determined	PI PIL
Sensahist EACH TABLET CONTAINS CETIRIZINE DIHYDROCHLORIDE 10,0 mg	Not listed	42082242/5.7.1/0822	Registered	Not determined	None
Cetirizine 10 shanur EACH TABLET CONTAINS :CETIRIZINE DIHYDROCHLORIDE 10,0 mg	10	43035843/5.7.1/0358	Registered	Not determined	None
Zinallerg EACH TABLET CONTAINS CETIRIZINE DIHYDROCHLORIDE 10,0 mg	Not listed	43035943/5.7.1/0359	Registered	Not determined	None
AURO cetirizine tablets 5 MG EACH TABLET CONTAINS CETIRIZINE DIHYDROCHLORIDE 5,0 mg	5 mgFilm-coated tablet	43064343/5.7.1/0643Approved 3 November 2022	Registered	S2	PI PIL
AURO cetirizine tablets 10 MG EACH TABLET CONTAINS CETIRIZINE DIHYDROCHLORIDE 10,0 mg	10 mgFilm-coated tablet	43064443/5.7.1/0644Approved 3 November 2022	Registered	S2	PI PIL
Trantrin tablets 5 MG EACH TABLET CONTAINS CETIRIZINE DIHYDROCHLORIDE 5,0 mg	5 mgTablets	43064543/5.7.1/0645	Registered	Not determined	None
Trantrin tablets 10 MG EACH TABLET CONTAINS CETIRIZINE DIHYDROCHLORIDE 10,0 mg	10 mgTablets	43064643/5.7.1/0646	Registered	Not determined	None
Allesoothe EACH TABLET CONTAINS CETIRIZINE DIHYDROCHLORIDE EQUIVALENT TO CETIRIZINE 10,0 mg	10 mgFilm-coated tablets.	48119748/5.7.1/1197Approved 27 February 2025	Registered	S2	PI PIL
Zialdel 5 mg/5 ML oral solution EACH 5,0 ml SOLUTION CONTAINS CETIRIZINE DIHYDROCHLORIDE 5,0 mg	5 mg/5 mlOral solution	53040453/5.7.1/0404	Registered	Not determined	None
Derasip 5 mg/5 ML oral solution EACH 5,0 ml SOLUTION CONTAINS CETIRIZINE DIHYDROCHLORIDE 5,0 mg	5 mg/5 mlOral solution	530405.40453/5.7.1/0405.404	Registered	Not determined	None
Cetriliqe EACH TABLET CONTAINS: CETIRIZINE HYDROCHLORIDE 10,0 mg	Not listed	58026058/5.7.1/0260	Registered	Not determined	None
Cetirizine oral solution unimed EACH 1,0 ml SOLUTION CONTAINS CETIRIZINE DIHYDROCHLORIDE 1,0 mg	Oral solution	A390103A39/5.7.1/0103	Registered	Not determined	None
Cetirizine 10 unimed EACH TABLET CONTAINS CETIRIZINE DIHYDROCHLORIDE 10,0 mg	10	A390384A39/5.7.1/0384	Registered	Not determined	None
Zyrtec tablet 10 MG EACH TABLET CONTAINS CETIRIZINE DIHYDROCHLORIDE 10 mg	10 mgTablet	W0148W/5.7.1/148	Registered	Not determined	None

Regulatory status

Where S2 sits on the scale

S0S1S2S3S4S5S6S7S8

A pharmacist can sell it directly, without a prescription.

Schedule 2 medicines sit behind the pharmacy counter. A pharmacist can decide to sell one of these directly, using their own professional judgement, without a doctor's prescription. It can also be dispensed against a prescription like the higher tiers, in which case the usual repeat limits apply. A child under 12 may only be sold a Schedule 2 substance on a prescription, or on a written order that names the purpose and carries a signature the seller recognises. Even though it cannot be advertised to the public in the ordinary sense, its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S2, read from the product's PI-PIL leaflet.

The Consolidated Schedules list this ingredient up to S1; the leaflet's S2 applies to this product.

Who may supply: Only a pharmacist, pharmacist intern or supervised pharmacist's assistant may sell it without a prescription. It may otherwise be dispensed by a pharmacist against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Cetirizine dihydrochloride

S1: Cetirizine
Consolidated Schedules 06 July 2026, line 318

Pharmacological class: Antihistaminics. (class 5.7.1)

5 of 11 approved products with this ingredient carry S2 on their leaflet.

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Professional information (PI)For healthcare professionalsCeticit syrup, Adcock ingram limited Patient information leaflet (PIL)For patients and carersCeticit syrup, Adcock ingram limited

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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