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Ephedrine

Schedule 1 to 6, conditions apply
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C10H15NO165.23 g/mol

(1R,2S)-2-(Methylamino)-1-phenylpropan-1-ol

Drag to rotate. Structure from PubChem CID 9294.

Background

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Listing

Schedules
Schedule 1 to 6, conditions apply
Source
Consolidated Schedules 06 July 2026

Registered medicines

10 registered products listed

Counted through the register's ingredient index, which does not reach every record.

Registered products
NameBrandsDosagesApplicantsRegistrationsSchedule
Caffeine, chlorpheniramine, ephedrine, paracetamolSinuend, Flusin, Sinucon200 mg/6 mg/ 20 mg/2 mg2 applicants3 registrationsS2
Chlorpheniramine, ephedrine, paracetamolGrippon cold and flu, Colcleersyrup, tabletsAdcock ingram limited2 registrationsS1 to S6conditions apply
Ascorbic acid, caffeine, ephedrine, thiamine, vitamin a CancelledBe-leane slimmingcapsulesThe Premier Pharmaceutical Co LtdE1251S1 to S6conditions apply
Codeine, ephedrine, mepyramineKiddiekof, Resmed mephcotusNot stated2 applicants2 registrationsS1 to S6conditions apply
Codeine, ephedrine, promethazineLenazine forte cough, Antituss cough, Sedlinct, +2 more9 mg/7,2 mg/3,6 mg per 5 ml, linctus, mixture, syrup3 applicants5 registrationsS2
EphedrineEphedrine hydrochloride lennon, Ipesandrine, Ephedrine hydrochloride, +2 more30 mg -, 30 MG, 60 MG, mixture, +1 more5 applicants6 registrationsS1 to S6conditions apply
Ephedrine, mepyramineDykatuss colinctusVesta Medicines (Pty) LtdG0664S1 to S6conditions apply
Chlorpheniramine, codeine, ephedrine CancelledPhen e codmixtureThe Premier Pharmaceutical Co LtdG0747S1 to S6conditions apply
Dextromethorphan, doxylamine, ephedrine, paracetamolVicks mediniteNot statedProcter & Gamble South Africa Trading (Pty) LtdH0140S1 to S6conditions apply
Dextromethorphan, diphenhydramine, ephedrine, paracetamol CancelledColcaps nite medNot statedAdcock ingram limitedS0155S1 to S6conditions apply

1 more registered product name Ephedrine in their active ingredient

Registered products
NameBrandsDosagesApplicantsRegistrationsSchedule
Ephedrine, eucalyptus oil, menthol, sodium bromide, thyme tinctureBronchicumelixirSanofi-aventis South Africa (Pty) LtdG0634

Regulatory status

Where S1 to S6 sits on the scale

Depends on which listing applies

At the least restrictive, Schedule 1: sold by a pharmacist, no doctor's prescription needed. At the most restrictive, Schedule 6: prescription-only, no repeats without a new prescription. The listings below say which applies to which form, strength or pack size.

Schedule S1 to S6, as the Consolidated Schedules list it.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it.

Consolidated Schedules listings for Ephedrine

  • S6: Ephedrine

    • except products registered in terms of the Act, not intended for export, and being oral preparations and mixtures, in combination with another pharmacologically active substance and intended for the symptomatic relief of colds and flu, containing not more than 30 milligrams of ephedrine per dose, with a maximum daily dose not exceeding 120 milligrams, subject to a maximum pack size of 360 milligrams and limited to one pack per customer; (S2)
    • except preparations and mixtures intended for application to the skin, eyes, ears and nares and containing 1 percent or less of ephedrine. (S1)

    Consolidated Schedules 06 July 2026, lines 10226 to 10235

  • S2: Ephedrine

    • contained in products registered in terms of the Act, and not intended for export,
    • oral preparations and mixtures, in combination with another pharmacologically active substance and intended for the symptomatic relief of colds and flu, containing not more than 30 milligrams of ephedrine per dose, with a maximum daily dose not exceeding 120 milligrams, subject to a maximum pack size of 360 milligrams and limited to one pack per customer; (S6)
    • except preparations and mixtures intended for application to the skin, eyes, ears and nares and containing 1 percent or less of ephedrine. (S1)

    Consolidated Schedules 06 July 2026, lines 1899 to 1907

  • S1: Ephedrine

    • preparations and mixtures intended for application to the skin, eyes, ears and nares and containing 1 percent or less of ephedrine, and not intended for export; (S6)
    • except products registered in terms of the Act, not intended for export, and being oral preparations and mixtures, in combination with another pharmacologically active substance and intended for the symptomatic relief of colds and flu, containing not more than 30 milligrams of ephedrine per dose, with a maximum daily dose not exceeding 120 milligrams, subject to a maximum pack size of 360 milligrams and limited to one pack per customer. (S2)

    Consolidated Schedules 06 July 2026, lines 410 to 419

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

Research articles

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