Diphenoxin
1-(3-Cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid
Drag to rotate. Structure from PubChem CID 34328.
Background
Listing
- Schedules
- Schedule 2 to 6, conditions apply
- Source
- Consolidated Schedules 06 July 2026
Registered medicines
The ingredient index links no registered medicine to Diphenoxin (register of 13 September 2026).
Counted through the register's ingredient index, which does not reach every record.
Regulatory status
Where S2 to S6 sits on the scale
Depends on which listing applies
At the least restrictive, Schedule 2: a pharmacist can sell it directly, without a prescription. At the most restrictive, Schedule 6: prescription-only, no repeats without a new prescription. The listings below say which applies to which form, strength or pack size.
Schedule S2 to S6, as the Consolidated Schedules list it.
Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it.
Consolidated Schedules listings for Diphenoxin
S6: Diphenoxin (or diphenoxylic acid)
- except mixtures containing, per dosage unit, 0,5 milligrams or less of difenoxin, calculated as the base, and a quantity of atropine sulphate equal to at least 5 percent of such quantity of difenoxin, calculated as the base, as is present in the mixture. (S2)
Consolidated Schedules 06 July 2026, lines 10194 to 10196
S2: Diphenoxin (or diphenoxylic acid)
- mixtures containing, per dosage unit, 0,5 milligrams or less of difenoxin, calculated as the base, and a quantity of atropine sulphate equal to at least 5 percent of such quantity of difenoxin, calculated as the base, as is present in the mixture. (S6)
Consolidated Schedules 06 July 2026, lines 1825 to 1827
This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.