Chlorpheniramine

Schedule 2

C₁₆H₁₉ClN₂274.79 g/mol

3-(4-Chlorophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine

Drag to rotate. Structure from PubChem CID 2725.

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Listing

Schedules: Schedule 2
Source: Consolidated Schedules 06 July 2026

Registered medicines

29 registered products listed

Counted through the register's ingredient index, which does not reach every record.

Registered products
Name	Brands	Dosages	Applicants	Registrations	Schedule
Chlorpheniramine	Histabate, Rhineton, Allerchlor, +8 more	4 mg, 5 ml, syrup, tablets, +3 more	6 applicants	14 registrations	S2
Aspirin, chlorpheniramine, pseudoephedrine, vitamin c	Coryx cold and flu	Not stated	Cipla Medpro (Pty) Ltd	270435	S1 to S6conditions apply
Caffeine, chlorpheniramine, paracetamol, phenylephrine, vitamin c	Sinustat flu, Flustat, Degoran c, +1 more	capsules, 5 mg	4 applicants	4 registrations	S1 to S4conditions apply
Chlorpheniramine, pseudoephedrine, vitamin c	Flusin-c	Not stated	Pharmacare limited û woodmead	270523	S1 to S6conditions apply
Chlorpheniramine, dextromethorphan, pseudoephedrine, vitamin c	Flusin dm	Not stated	Pharmacare limited û woodmead	270553	S1 to S6conditions apply
Caffeine, chlorpheniramine, paracetamol, pseudoephedrine	Flusin	capsules	Pharmacare limited û woodmead	280273	S1 to S6conditions apply
Chlorpheniramine, phenylephrine, phenylpropanolamine	Betalix decongestant, Rinex, Rinex diffucaps, +1 more	5 ml, syrup	3 applicants	4 registrations	S1 to S6conditions apply
Chlorpheniramine, paracetamol, pseudoephedrine	Sinumax allergy sinus ped liquid, Sinumax allergy sinus, Sinutab sinus allergy congestion and pain, +1 more	5 ml, 30 mg	4 applicants	4 registrations	S2
Caffeine, chlorpheniramine, ephedrine, paracetamol	Sinuend, Flusin, Sinucon	200 mg/6 mg/ 20 mg/2 mg	2 applicants	3 registrations	S2
Chlorpheniramine, paracetamol, pseudoephedrine, vitamin c	Flusin s, Endcol c, Flutex fizzy, +3 more	50 mg/ 4 mg/ 500 mg/ 330 mg, effervescent	Pharmacare limited û woodmead	6 registrations	S2
Chlorpheniramine, codeine, paracetamol, pseudoephedrine	Sinutab sinus pain extra strength	2 mg, 10 mg, 500 mg	Johnson & Johnson (Pty) Ltd û East London	370139	S2
Chlorpheniramine, paracetamol, vitamin c	Coryx para c, Paragrip c, Efferflu-c cold & flu	250 mg	3 applicants	3 registrations	S2

Show the other 17 registered products

Registered products
Name	Brands	Dosages	Applicants	Registrations	Schedule
Chlorpheniramine, ibuprofen, phenylephrine	Corenza with ibuprofen, Grippon fizz with ibuprofen	effervescent tablets	Adcock ingram limited	2 registrations	S1 to S4conditions apply
Chlorpheniramine, codeine, paracetamol Cancelled	Meprogesic paediatric	syrup	The Premier Pharmaceutical Co Ltd	B1417	S1 to S6conditions apply
Aspirin, caffeine, chlorpheniramine, dextropropoxyphene, paracetamol Cancelled	Propoxan	Not stated	Keatings	B1542	S1 to S6conditions apply
Chlorpheniramine, phenylephrine	Demazin, Asalen paediatric	1,25 mg and 2,5 mg,, syrup	2 applicants	2 registrations	S2
Atropine, chlorpheniramine, phenylpropanolamine Cancelled	Contac	600	Smith Kline French (Pty) Ltd *	C0630	S2 to S6conditions apply
Caffeine, chlorpheniramine, paracetamol, phenylephrine	Degoran plus, Grippon cold and flu, Histacon	capsules	2 applicants	3 registrations	S1 to S4conditions apply
Aspirin, caffeine, chlorpheniramine, phenylephrine	Dristan	tablet	Pfizer Laboratories (Pty) Ltd	C0717	S1 to S4conditions apply
Chlorpheniramine, ephedrine, paracetamol	Grippon cold and flu, Colcleer	syrup, tablets	Adcock ingram limited	2 registrations	S1 to S6conditions apply
Ascorbic acid, caffeine, chlorpheniramine, paracetamol, phenylephrine	Grippon, Dristan cold & flu	capsules	2 applicants	2 registrations	S1 to S4conditions apply
Chlorpheniramine, paracetamol, phenylephrine	Dequa-flu	Not stated	Micro Healthcare (Pty) Ltd	C0879	S1 to S4conditions apply
Atropine, caffeine, chlorpheniramine, paracetamol, phenylephrine, vitamin c	Colstat	300 mg	Lebasi Pharmaceuticals (Pty) Ltd	C0955	S2
Chlorpheniramine, dextromethorphan, paracetamol, phenylpropanolamine	Degoran, Nitecall, Degoran t, +1 more	Not stated	3 applicants	4 registrations	S1 to S6conditions apply
Chlorpheniramine, codeine, ephedrine Cancelled	Phen e cod	mixture	The Premier Pharmaceutical Co Ltd	G0747	S1 to S6conditions apply
Ascorbic acid, atropine, caffeine, chlorpheniramine, paracetamol, phenylephrine	Famucaps	2 mg	Brunel Laboratoria (Pty) Ltd	G1235	S2
Chlorpheniramine, pseudoephedrine Cancelled	Isochlor, Isochlor liquid, Isochlor timesules	tablets	The Premier Pharmaceutical Co Ltd	3 registrations	S2 to S6conditions apply
Aspirin, caffeine, chlorpheniramine, vitamin c	Nitroflu cold and flu, Ultraviro c	capsules	2 applicants	2 registrations	S1 to S3conditions apply
Anhydrous, caffeine, chlorpheniramine, paracetamol, phenylephrine, vitamin c Cancelled	Cepacol cold	capsules	Adcock ingram limited	R0247	S1 to S4conditions apply

4 more registered products name Chlorpheniramine in their active ingredient

Registered products
Name	Brands	Dosages	Applicants	Registrations
Chlorpheniramine, hyoscine methonitrate, pholcodine, pseudoephedrine Cancelled	Respinol compound	linctus	Innovata pharmaceuticals	B0214
Chlorpheniramine, hyoscine methonitrate, phenylephrine	Dyka-d, Respinol elixer, Respinol tydales	Not stated	2 applicants	3 registrations
Chlorpheniramine, codeine, ephedrine, guaifenesin Cancelled	Corbar	linctus	Adcock ingram limited	G1032
Chlorpheniramine, dextromethorphan, guaifenesin, phenylephrine	Dristan decongestant cough medicine	Not stated	Pharmacare limited û woodmead	G1043

Regulatory status

Where S2 sits on the scale

S0S1S2S3S4S5S6S7S8

A pharmacist can sell it directly, without a prescription.

Schedule 2 medicines sit behind the pharmacy counter. A pharmacist can decide to sell one of these directly, using their own professional judgement, without a doctor's prescription. It can also be dispensed against a prescription like the higher tiers, in which case the usual repeat limits apply. A child under 12 may only be sold a Schedule 2 substance on a prescription, or on a written order that names the purpose and carries a signature the seller recognises. Even though it cannot be advertised to the public in the ordinary sense, its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S2, as the Consolidated Schedules list it.

Who may supply: Only a pharmacist, pharmacist intern or supervised pharmacist's assistant may sell it without a prescription. It may otherwise be dispensed by a pharmacist against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Chlorpheniramine

S2: Chlorpheniramine
Consolidated Schedules 06 July 2026, line 1732

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

Research articles

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