Cyclizine

Sold as Medazine nausea, Medazine s, Adco-cyclizine, Ryccard /tablette, Ryccard ped, Nauzine*, Emitex, Covamet, Cycloid /stoop, Cycloid, Nauzine s, Pinaloid, Valoid as, Valoid children's, Valoid, Valoid paediatric, Triazine, Maldemar, Aculoid, Norizine, Triazine paediatric

S2Read from the PI-PIL document and verified

C₁₈H₂₂N₂266.40 g/mol

1-Benzhydryl-4-methylpiperazine

Drag to rotate. Structure from PubChem CID 6726.

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Registration

Applicants: 8
Registrations: 27
Schedule source: SAHPRA documentation

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Cipla Medpro (Pty) Ltd	Medazine nausea	tablets	270203	Not determined	None
Medpro Pharmaceutica (Pty) LtdCertificate held by Cipla Medpro (Pty) Ltd.1 of 2 cancelled	Medazine s, Pinaloid	5 ml	270204, 330466	S2	PI PIL
Adcock ingram limited3 of 6 cancelled	Adco-cyclizine, Ryccard /tablette, Ryccard ped, Covamet	syrup, 50 mg, tablets/tablette, tablets	270259, 270386, 270484, 270503, 280499, 280533	Not determined	None
Ranbaxy (SA) (Pty) LtdCancelled	Nauzine*, Nauzine s	tablet	270535, 290238	Not determined	None
Pharmacare limited û woodmead4 of 11 cancelled	Emitex, Valoid as, Valoid children's, Valoid, Valoid paediatric, Triazine, Norizine, Triazine paediatric	tablets, syrup, suppositories, 50 mg, 100 mg	280435, 280436, C0975, C0977, C0978, D0097, M0160, M0161, N0168, X0200, X0382	Not determined	None
Acino Pharma (Pty) Ltd	Cycloid /stoop, Cycloid	syrup/stoop, tablets	280705, 290032	Not determined	None
The Premier Pharmaceutical Co LtdCancelled	Maldemar	Not stated	V0335	Not determined	None
Teva Pharmaceuticals (Pty) LtdCancelled	Aculoid	syrup, tablets	X0005, Z0228	Not determined	None

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Medazine nausea tablets EACH TABLET CONTAINS CYCLIZINE HYDROCHLORIDE 50 mg	Tablets	27020327/5.7.2/0203	Registered	Not determined	None
Medazine s 5 ML CYCLIZINE HYDROCHLORIDE 12,5 MG	5 mlSyrup	27020427/5.7.2/0204Approved 20 February 2023	Registered	S2	PI PIL
Adco-cyclizine syrup EACH 5 ml SYRUP CONTAINS CYCLIZINE HYDROCHLORIDE 12,5 mg	Syrup	27025927/5.7/0259	Registered	Not determined	None
Adco-cyclizine 50 MG EACH TABLET CONTAINS CYCLIZINE HYDROCHLORIDE 50 mg	50 mg	27038627/5.7.2/0386	Registered	Not determined	None
Ryccard tablets/tablette EACH TABLET CONTAINS CYCLIZINE HYDROCHLORIDE 50 mg	Tablets/tablette	27048427/5.7.2/0484	Cancelled	Not determined	None
Ryccard ped EACH 5 ml SYRUP CONTAINS CYCLIZINE HYDROCHLORIDE 12,5 mg	Not listed	27050327/5.7/0503	Cancelled	Not determined	None
Nauzine* tablet EACH TABLET CONTAINS CYCLIZINE HYDROCHLORIDE 50 mg	Tablet	27053527/5.7.2/0535	Cancelled	Not determined	None
Emitex tablets EACH TABLET CONTAINS CYCLIZINE HYDROCHLORIDE 50 mg	Tablets	28043528/5.7.2/0435	Registered	Not determined	None
Emitex syrup EACH 5 ml CONTAINS CYCLIZINE HYDROCHLORIDE 12,5 mg	Syrup	28043628/5.7/0436	Cancelled	Not determined	None
Covamet tablets EACH TABLET CONTAINS CYCLIZINE HYDROCHLORIDE 50 mg	Tablets	28049928/5.7/0499	Registered	Not determined	None
Covamet syrup EACH 5,0 ml SYRUP CONTAINS CYCLIZINE HYDROCHLORIDE 12,5 mg	Syrup	28053328/5.7/0533	Cancelled	Not determined	None
Cycloid syrup/stoop EACH 5 ML SYRUP CONTAINS CYCLIZINE HYDROCHLORIDE 12,5 MG	Syrup/stoop	28070528/5.7/0705	Registered	Not determined	None
Cycloid tablets TABLET CYCLIZINE HYDROCHLORIDE 50 MG	Tablets	29003229/5.7.2/0032	Registered	Not determined	None
Nauzine s* EACH 5 ml SYRUP CONTAINS CYCLIZINE HYDROCHLORIDE 12,5 mg	Not listed	29023829/5.7.2/0238	Cancelled	Not determined	None
Pinaloid EACH TABLET CONTAINS CYCLIZINE HYDROCHLORIDE 50,0 mg	Not listed	33046633/5.7.2/0466	Cancelled	Not determined	None
Valoid as EACH SUPPOSITORY CONTAINS CYCLIZINE HYDROCHLORIDE 100,0 mg	Not listed	C0975C/5.7.2/975	Registered	Not determined	None
Valoid children's suppositories EACH SUPPOSITORY CONTAINS CYCLIZINE HYDROCHLORIDE 50,0 mg	Suppositories	C0977C/5.7.2/977	Registered	Not determined	None
Valoid EACH TABLET CONTAINS CYCLIZINE HYDROCHLORIDE 50 mg	Not listed	C0978C/5.7.2/978	Registered	Not determined	None
Valoid paediatric syrup EACH 5,0 ml SYRUP CONTAINS CYCLIZINE HYDROCHLORIDE 12,5 mg	Syrup	D0097D/5.7/97	Registered	Not determined	None
Triazine 50 MG suppositories EACH SUPPOSITORY CONTAINS CYCLIZINE HYDROCHLORIDE 50 mg	50 mgSuppositories	M0160M/5.7.2/160	Cancelled	Not determined	None
Triazine 100 MG suppositories EACH SUPPOSITORY CONTAINS CYCLIZINE HYDROCHLORIDE 100 mg	100 mgSuppositories	M0161M/5.7.2/161	Cancelled	Not determined	None
Triazine tablets EACH TABLET CONTAINS CYCLIZINE HYDROCHLORIDE 50 mg	Tablets	N0168N/5.7.2/168	Registered	Not determined	None
Maldemar* EACH TABLET CONTAINS CYCLIZINE HYDROCHLORIDE 50 mg	Not listed	V0335V/5.7.2/335	Cancelled	Not determined	None
Aculoid syrup EACH 5 ml SOLUTION CONTAINS CYCLIZINE HYDROCHLORIDE 12,5 mg	Syrup	X0005X/5.7/5	Cancelled	Not determined	None
Norizine tablets EACH TABLET CONTAINS CYCLIZINE HYDROCHLORIDE 50 mg	Tablets	X0200X/5.7/200	Cancelled	Not determined	None
Triazine paediatric syrup EACH 5 ml SYRUP CONTAINS CYCLIZINE HYDROCHLORIDE 12,5 mg	Syrup	X0382X/5.7/382	Registered	Not determined	None
Aculoid tablets EACH TABLET CONTAINS CYCLIZINE HYDROCHLORIDE 50 mg	Tablets	Z0228Z/5.7.2/228	Cancelled	Not determined	None

Regulatory status

Where S2 sits on the scale

S0S1S2S3S4S5S6S7S8

A pharmacist can sell it directly, without a prescription.

Schedule 2 medicines sit behind the pharmacy counter. A pharmacist can decide to sell one of these directly, using their own professional judgement, without a doctor's prescription. It can also be dispensed against a prescription like the higher tiers, in which case the usual repeat limits apply. A child under 12 may only be sold a Schedule 2 substance on a prescription, or on a written order that names the purpose and carries a signature the seller recognises. Even though it cannot be advertised to the public in the ordinary sense, its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S2, read from the product's PI-PIL leaflet.

Who may supply: Only a pharmacist, pharmacist intern or supervised pharmacist's assistant may sell it without a prescription. It may otherwise be dispensed by a pharmacist against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Cyclizine hydrochloride

S2: Cyclizine
Consolidated Schedules 06 July 2026, line 1785

Pharmacological class: Anti-emetics and antivertigo preparations. (class 5.7.2)

2 of 3 approved products with this ingredient carry S6 on their leaflet.

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

Medazine s, Medpro Pharmaceutica (Pty) Ltd is scheduled S2 in its official SAHPRA documents, read with 90% confidence.

Professional information (PI)For healthcare professionalsMedazine s, Medpro Pharmaceutica (Pty) Ltd Patient information leaflet (PIL)For patients and carersMedazine s, Medpro Pharmaceutica (Pty) Ltd

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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