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Xylometazoline

Schedule 1 to 2, conditions apply
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C16H24N2244.37 g/mol

2-[(4-tert-Butyl-2,6-dimethylphenyl)methyl]-4,5-dihydro-1H-imidazole

Drag to rotate. Structure from PubChem CID 5709.

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Listing

Schedules
Schedule 1 to 2, conditions apply
Source
Consolidated Schedules 06 July 2026

Registered medicines

2 registered products listed

Counted through the register's ingredient index, which does not reach every record.

Registered products
NameBrandsDosagesApplicantsRegistrationsSchedule
XylometazolineOtrivin menthol, Sinutab adult nasal, Sinutab children's nasal, +10 morespray, drops, 1 mg/mL, 127 applicants13 registrationsS1
Ipratropium, xylometazolineOtrivin plus, Tazomist duo, Sinustat duo nasal0.5 mg/ml + 0.6 mg/m, spray3 applicants3 registrationsS2

Regulatory status

Where S1 to S2 sits on the scale

Depends on which listing applies

At the least restrictive, Schedule 1: sold by a pharmacist, no doctor's prescription needed. At the most restrictive, Schedule 2: a pharmacist can sell it directly, without a prescription. The listings below say which applies to which form, strength or pack size.

Schedule S1 to S2, as the Consolidated Schedules list it.

Who may supply: Only a pharmacist, pharmacist intern or supervised pharmacist's assistant may sell it without a prescription. It may otherwise be dispensed by a pharmacist against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Xylometazoline

  • S2: Xylometazoline

    • except when intended for nasal use.

    Consolidated Schedules 06 July 2026, line 2767

  • S1: Xylometazoline

    • when intended for nasal use.

    Consolidated Schedules 06 July 2026, line 1211

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

Research articles

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