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Ketoprofen

Schedule 1 to 3, conditions apply
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C16H14O3254.28 g/mol

2-(3-Benzoylphenyl)propanoic acid

Drag to rotate. Structure from PubChem CID 3825.

Background

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Listing

Schedules
Schedule 1 to 3, conditions apply
Source
Consolidated Schedules 06 July 2026

Registered medicines

3 registered products listed

Counted through the register's ingredient index, which does not reach every record.

Registered products
NameBrandsDosagesApplicantsRegistrationsSchedule
Ceftiofur, ketoprofenCuracef duoNot statedVirbac Rsa (Pty) Ltd17/02S1 to S4conditions apply
KetoprofenKetink, Ketoflam, Ketofen, +2 more1 %, 2.5 g per 100 g, 5 mg, 10 %, +4 more4 applicants9 registrationsS3
Ketoprofen, tulathromycinDraxxin plus &100 mg/ml 120 mg/mlZoetis South Africa (Pty) Ltd21/05S1 to S4conditions apply

Regulatory status

Where S1 to S3 sits on the scale

Depends on which listing applies

At the least restrictive, Schedule 1: sold by a pharmacist, no doctor's prescription needed. At the most restrictive, Schedule 3: needs a doctor's prescription, dispensed by a pharmacist. The listings below say which applies to which form, strength or pack size.

Schedule S1 to S3, as the Consolidated Schedules list it.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Ketoprofen

  • S3: Ketoprofen

    • except when intended for application to the skin; (S1)
    • except when intended for the short term management of headache, toothache, muscular ache, backache, minor pain associated with arthritis, pain associated with menstrual cramps (dysmenorrhoea), minor aches and pains associated with the common cold and fever, subject to a maximum dose of 75 milligrams of ketoprofen in 24 hours; (S2)
    • except when intended for the emergency treatment of acute gout attacks or for the treatment of post- traumatic conditions, subject to a maximum dose of 75 milligrams of ketoprofen per day and a maximum treatment period of 5 days; (S2)
    • except in the form of lozenges indicated and intended for the relief of pain associated with sore throats in patients 18 years and older subject to- (i) a maximum of 12,5 milligrams per lozenge; (ii) a maximum of 5 lozenges in any 24 hour period; (iii) a maximum treatment period of 3 days; and (iv) a maximum pack size of 15 lozenges. (S2)

    Consolidated Schedules 06 July 2026, lines 3836 to 3858

  • S2: Ketoprofen

    • when intended for the short term management of headache, toothache, muscular ache, backache, minor pain associated with arthritis, pain associated with menstrual cramps (dysmenorrhoea), minor aches and pains associated with the common cold and fever, at a maximum dose of 75 milligrams of ketoprofen in 24 hours;
    • when intended for the emergency treatment of acute gout attacks or for the treatment of post-traumatic conditions, subject to a maximum dose of 100 milligrams of ketoprofen per day, for a maximum treatment period of 5 days;
    • in the form of lozenges indicated and intended for the relief of pain associated with sore throats in patients 18 years and older subject to- (i) a maximum of 12,5 milligrams per lozenge; (ii) a maximum of 5 lozenges in any 24 hour period; (iii) a maximum treatment period of 3 days; and (iv) a maximum pack size of 15 lozenges. (S3)
    • except when intended for application to the skin. (S1)

    Consolidated Schedules 06 July 2026, lines 2191 to 2220

  • S1: Ketoprofen

    • when intended for application to the skin; (S3)
    • except when intended for the short term management of headache, toothache, muscular ache, backache, minor pain associated with arthritis, pain associated with menstrual cramps (dysmenorrhoea), minor aches and pains associated with the common cold and fever, at a maximum dose of 75 milligrams of ketoprofen in 24 hours; (S2)
    • except when intended for the emergency treatment of acute gout attacks; (S2)
    • except when intended for the treatment of post-traumatic conditions, subject to a maximum dose of 100 milligrams of ketoprofen per day, for a maximum treatment period of 5 days; (S2)
    • except in the form of lozenges indicated and intended for the relief of pain associated with sore throats in patients 18 years and older subject to- (i) a maximum of 12,5 milligrams per lozenge; (ii) a maximum of 5 lozenges in any 24 hour period; (iii) a maximum treatment period of 3 days; and (iv) a maximum pack size of 15 lozenges. (S2)

    Consolidated Schedules 06 July 2026, lines 596 to 624

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

Research articles

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