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zameds

Dextromethorphan

Schedule 2
Loading the molecular structure
C18H25NO271.40 g/mol

(1S,9S,10S)-4-Methoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-triene

Drag to rotate. Structure from PubChem CID 5360696.

Background

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Listing

Schedules
Schedule 2
Source
Consolidated Schedules 06 July 2026

Registered medicines

15 registered products listed

Counted through the register's ingredient index, which does not reach every record.

Registered products
NameBrandsDosagesApplicantsRegistrationsSchedule
Dextromethorphan, pseudoephedrineBenylin dmd decongestant coughsyrupJohnson & Johnson (Pty) Ltd û East London270002S2 to S6conditions apply
Dextromethorphan, paracetamol, phenylpropanolamineSinustat flu, Flustatsyrup, 20 ml2 applicants2 registrationsS1 to S6conditions apply
Dextromethorphan, pseudoephedrine, triprolidineCoryx cough and cold, Tuscodin cm, Sinuclear cough, +3 more5 mL/10 mg/30 mg/1.25 mg, syrup, linctus4 applicants6 registrationsS2
Chlorpheniramine, dextromethorphan, pseudoephedrine, vitamin cFlusin dmNot statedPharmacare limited û woodmead270553S1 to S6conditions apply
Carbinoxamine, dextromethorphan, pseudoephedrine CancelledRondofen dmNot statedThe Premier Pharmaceutical Co Ltd290584S2 to S6conditions apply
DextromethorphanDilinct dry cough, Benylin solid, Benylin dry cough15 mg2 applicants3 registrationsS2
Dextromethorphan, paracetamol, phenylephrineFlusin day timecapsulesPharmacare limited û woodmead450480S1 to S4conditions apply
Chlorpheniramine, dextromethorphan, paracetamol, phenylpropanolamineDegoran, Nitecall, Degoran t, +1 moreNot stated3 applicants4 registrationsS1 to S6conditions apply
Dextromethorphan, diphenhydramine, paracetamol, pseudoephedrine, vitamin c CancelledFlu-medsyrupAdcock ingram limitedD0053S1 to S6conditions apply
Dextromethorphan, diphenhydramine, phenylephrine CancelledBenyphedNot statedJohnson & Johnson (Pty) Ltd û East LondonE0198S1 to S4conditions apply
Dextromethorphan, phenylpropanolamine CancelledOrnacolNot statedGlaxosmithkline South Africa (Pty) Limited2 registrationsS2 to S6conditions apply
Dextromethorphan, doxylamine, ephedrine, paracetamolVicks mediniteNot statedProcter & Gamble South Africa Trading (Pty) LtdH0140S1 to S6conditions apply
Show the other 3 registered products
Registered products
NameBrandsDosagesApplicantsRegistrationsSchedule
Dextromethorphan, diphenhydramine CancelledBenydexNot statedJohnson & Johnson (Pty) Ltd û East LondonH0319S2
Dextromethorphan, diphenhydramine, ephedrine, paracetamol CancelledColcaps nite medNot statedAdcock ingram limitedS0155S1 to S6conditions apply
Dextromethorphan, paracetamol, pseudoephedrine, vitamin cDemazin fluNot statedInova Pharmaceuticals (Pty) LtdY0308S1 to S6conditions apply

2 more registered products name Dextromethorphan in their active ingredient

Registered products
NameBrandsDosagesApplicantsRegistrationsSchedule
Dextromethorphan, diphenhydramine, ephedrine, guaifenesin CancelledLotussinlinctusJohnson & Johnson (Pty) Ltd û East LondonK0201
Dextromethorphan, guaifenesin, pseudoephedrine, triprolidineEndcol d coughsyrupPharmacare limited û woodmeadZ0120

Regulatory status

Where S2 sits on the scale

A pharmacist can sell it directly, without a prescription.

Schedule 2 medicines sit behind the pharmacy counter. A pharmacist can decide to sell one of these directly, using their own professional judgement, without a doctor's prescription. It can also be dispensed against a prescription like the higher tiers, in which case the usual repeat limits apply. A child under 12 may only be sold a Schedule 2 substance on a prescription, or on a written order that names the purpose and carries a signature the seller recognises. Even though it cannot be advertised to the public in the ordinary sense, its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S2, as the Consolidated Schedules list it.

Who may supply: Only a pharmacist, pharmacist intern or supervised pharmacist's assistant may sell it without a prescription. It may otherwise be dispensed by a pharmacist against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Dextromethorphan

  • S2: Dextromethorphan

    Consolidated Schedules 06 July 2026, line 1801

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

Research articles

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