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Indometacin

Schedule 1 to 3, conditions apply
Loading the molecular structure
C19H16ClNO4357.80 g/mol

2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid

Drag to rotate. Structure from PubChem CID 3715.

Background

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Listing

Schedules
Schedule 1 to 3, conditions apply
Source
Consolidated Schedules 06 July 2026

Registered medicines

The ingredient index links no registered medicine to Indometacin (register of 13 September 2026).

Counted through the register's ingredient index, which does not reach every record.

Regulatory status

Where S1 to S3 sits on the scale

Depends on which listing applies

At the least restrictive, Schedule 1: sold by a pharmacist, no doctor's prescription needed. At the most restrictive, Schedule 3: needs a doctor's prescription, dispensed by a pharmacist. The listings below say which applies to which form, strength or pack size.

Schedule S1 to S3, as the Consolidated Schedules list it.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Indometacin

  • S3: Indometacin

    • except for application to the skin (S1), and
    • except for the emergency treatment of acute gout attacks (S2).

    Consolidated Schedules 06 July 2026, lines 3782 to 3786

  • S2: Indometacin

    • when intended for the emergency treatment of acute gout attacks; (S3)
    • except when intended for application to the skin; (S1)
    • except when intended for veterinary use. (S3)

    Consolidated Schedules 06 July 2026, lines 2167 to 2173

  • S1: Indometacin

    • when intended for application to the skin; (S3)
    • except when intended for the emergency treatment of acute gout attacks; (S2)
    • except when intended for veterinary use. (S3)

    Consolidated Schedules 06 July 2026, lines 554 to 564

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

Research articles

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