Hyaluronic acid
Listed in the Consolidated Schedules as “Hyaluronic acid and its salts”
No structure available
Hyaluronic acid could not be matched to a single known compound.
Background
Listing
- Schedules
- Schedule 1 to 4, conditions apply
- Exceptions reach
- Schedule 0
- Source
- Consolidated Schedules 06 July 2026
Registered medicines
The ingredient index links no registered medicine to Hyaluronic acid (register of 13 September 2026).
Counted through the register's ingredient index, which does not reach every record.
Regulatory status
Where S1 to S4 sits on the scale
Depends on which listing applies
At the least restrictive, Schedule 1: sold by a pharmacist, no doctor's prescription needed. At the most restrictive, Schedule 4: prescription-only medicine. The listings below say which applies to which form, strength or pack size.
Schedule S1 to S4, as the Consolidated Schedules list it.
Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.
Consolidated Schedules listings for Hyaluronic acid
S4: Hyaluronic acid
- when intended for parenteral use;
- except when intended for use with contact lens solutions or as an ophthalmic lubricant in concentrations of not more than 0,1 percent; (S0)
- except when intended for topical application to the skin; (S1)
- except when intended for ophthalmic use in preparations (except injectables) containing more than 0,1 percent;(S2)
- except in preparations containing less than 2,5 percent when intended for topical use in terms of the provisions of the Foodstuffs, Cosmetics and Disinfectants Act, 1972 (Act 54 of 1972).
Consolidated Schedules 06 July 2026, lines 6626 to 6645
S2: Hyaluronic acid
- when intended for ophthalmic use in preparations (except injectables) containing more than 0,1 percent;
- except when intended for use with contact lens solutions or as an ophthalmic lubricant in concentrations of not more than 0,1 percent; (S0)
- except when intended for topical application to the skin; (S1)
- except when intended for parenteral use; (S4)
- except in preparations containing less than 2,5 percent when intended for topical use in terms of the provisions of the Foodstuffs, Cosmetics and Disinfectants Act, 1972 (Act 54 of 1972).
Consolidated Schedules 06 July 2026, lines 2097 to 2109
S1: Hyaluronic acid
- when intended for topical application to the skin;
- except when intended for use with contact lens solutions or as an ophthalmic lubricant in concentrations of not more than 0,1 percent; (S0)
- except when intended for ophthalmic use in preparations (except injectables) containing more than 0,1 percent; (S2)
- except when intended for parenteral use; (S4)
- except in preparations containing less than 2,5 percent when intended for topical use in terms of the provisions of the Foodstuffs, Cosmetics and Disinfectants Act, 1972 (Act 54 of 1972).
Consolidated Schedules 06 July 2026, lines 494 to 512
This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.