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Triprolidine

Schedule 2
Loading the molecular structure
C19H22N2278.40 g/mol

2-[(E)-1-(4-Methylphenyl)-3-pyrrolidin-1-ylprop-1-enyl]pyridine

Drag to rotate. Structure from PubChem CID 5282443.

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Listing

Schedules
Schedule 2
Source
Consolidated Schedules 06 July 2026

Registered medicines

6 registered products listed

Counted through the register's ingredient index, which does not reach every record.

Registered products
NameBrandsDosagesApplicantsRegistrationsSchedule
Codeine, pseudoephedrine, triprolidineAdco-tussend, Tuscodin co, Fludactil co, +4 morelinctus6 applicants7 registrationsS2 to S6conditions apply
Paracetamol, pseudoephedrine, triprolidineAdco flupain, Sinuclear paediatric /stroop, Acuflu p stroop1,5 g, syrup/stroop, /3 applicants3 registrationsS2
Dextromethorphan, pseudoephedrine, triprolidineCoryx cough and cold, Tuscodin cm, Sinuclear cough, +3 more5 mL/10 mg/30 mg/1.25 mg, syrup, linctus4 applicants6 registrationsS2
Pseudoephedrine, triprolidineFlusin sinus, Betafed, Actifed cold, +4 moresyrup, 5 ml, tablets4 applicants8 registrationsS2
Pseudoephedrine, triprolidine, vitamin cCoryx paediatric5 mLCipla Medpro (Pty) Ltd310056S1 to S6conditions apply
TriprolidineActidil, Triprolidine hydrochloride2 mg/ 5 ml2 applicants3 registrationsS2

Regulatory status

Where S2 sits on the scale

A pharmacist can sell it directly, without a prescription.

Schedule 2 medicines sit behind the pharmacy counter. A pharmacist can decide to sell one of these directly, using their own professional judgement, without a doctor's prescription. It can also be dispensed against a prescription like the higher tiers, in which case the usual repeat limits apply. A child under 12 may only be sold a Schedule 2 substance on a prescription, or on a written order that names the purpose and carries a signature the seller recognises. Even though it cannot be advertised to the public in the ordinary sense, its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S2, as the Consolidated Schedules list it.

Who may supply: Only a pharmacist, pharmacist intern or supervised pharmacist's assistant may sell it without a prescription. It may otherwise be dispensed by a pharmacist against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Triprolidine

  • S2: Triprolidine

    Consolidated Schedules 06 July 2026, line 2745

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

Research articles

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