Acetylcysteine

Sold as Solmucol, Acc, Aloribex, Amuco, Amuco otc, Pholtex mucus, Paradote, Muco-go, Mucatak, Mucofizz, Acc on the go, Tussmuco, Gencetyl, Ukastyn, Rocylteine, Mucoloc, Acetylcysteine austell, Acetylcysteine camox, Corenza muco, Acetylcysteine adco, Flemkleer, Acetylcysteine clicks, Acetylcysteine sandoz, Acetylcysteine hexal, Acc hot, Parvolex, Mucolit

S3Read from the PI-PIL document and verified

C₅H₉NO₃S163.20 g/mol

(2R)-2-Acetamido-3-sulfanylpropanoic acid

Drag to rotate. Structure from PubChem CID 12035.

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Registration

Applicants: 11
Registrations: 37
Schedule source: SAHPRA documentation

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Pharmacare limited û woodmeadCertificate held by Pharmacare Ltd, Aspen pharmacare1 of 7 cancelled	Solmucol, Tussmuco, Parvolex, Mucolit	100, 200, 200mg / 10ml, 400, 600 mg	280128, 280129, 280451, 540854, 590104, NX0156, W0247	S2S1 to S2 by pack	PI PIL
Sandoz South Africa (Pty) LtdCertificate held by Sandoz SA (Pty) Ltd, Sandoz SA (Pty) Ltd1	Acc, Acc on the go, Acetylcysteine clicks, Acetylcysteine sandoz, Acetylcysteine hexal, Acc hot	200 mg, 600 mg	290753, 450229, 510816, 580222, 590060, 590061.060, 590406	Not determined	PI PIL
Ipharma (Pty) Ltd	Aloribex	300	340178	S3	PI PIL
Austell Pharmaceuticals (Pty) Ltd	Amuco, Amuco otc, Acetylcysteine austell, Acetylcysteine camox	200, 600 mg	430510, 430511, 570586, 570587.586, 570588.586	Not determined	None
Inova Pharmaceuticals (Pty) Ltd	Pholtex mucus	200 mg	430512	S1	PI PIL
Equity Pharmaceutical (Pty) LtdCertificate held by Equity Pharmaceuticals (Pty) Ltd	Paradote	200 mg	440329	Not determined	PI PIL
Cipla Medpro (Pty) Ltd	Muco-go, Mucatak	200	440925, 440927	Not determined	None
Pharma Dynamics (Pty) Ltd	Mucofizz	200 mg	460384	S1	PI PIL
Aurogen South Africa (Pty) Ltd2 of 6 cancelled	Gencetyl, Ukastyn, Rocylteine	200 mg, 600 mg	560139, 560140, 560141.139, 560142.140, 560143.139, 560144.140	Not determined	None
Adcock ingram limited	Mucoloc, Corenza muco, Acetylcysteine adco	200, 600	570362, 570863, 570864, 570865.863, 570866.864	S1	PI PIL
Dezzo Trading 392 (Pty) Ltd	Flemkleer	200	580186	Not determined	None

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Solmucol 200 EACH SACHET CONTAINS ACETYLCYSTEINE 200 mg	200	28012828/10.2.2/0128	Registered	Not determined	None
Solmucol 400 EACH SACHET CONTAINS ACETYLCYSTEINE 400,0 mg	400	28012928/10.2.2/0129	Registered	Not determined	None
Solmucol EACH LOZENGE CONTAINS ACETYLCYSTEINE 100 mg	Not listed	28045128/10.2.2/0451	Registered	Not determined	None
Acc 200 EACH TABLET CONTAINS ACETYLCYSTEINE 200 mg	200 mgEffervescent tablets	29075329/10.2.2/0753Approved 19 April 2013	Registered	Not determined	PIL
Aloribex 300 EACH 3,0 g SACHET CONTAINS ACETYLCYSTEINE 200,0 mg	300Tablets.	34017834/3.3/0178Approved 19 April 2023	Registered	S3	PI PIL
Amuco 200 effervescent tablets EACH EFFERVESCENT TABLET CONTAINS :ACETYLCYSTEINE 200,0 mg	200Effervescent tablets	43051043/10.2.2/0510	Registered	Not determined	None
Amuco 200 otc EACH EFFERVESCENT TABLET CONTAINS ACETYLCYSTEINE 200,0 mg	200	43051143/10.2.2/0511	Registered	Not determined	None
Pholtex mucus 200 EACH EFFERVESCENT TABLET CONTAINS ACETYLCYSTEINE 200,0 mg	200 mgEffervescent tablets	43051243/10.2.2/0512Approved 4 October 2022	Registered	S1	PI PIL
Paradote EACH 1,0 ml SOLUTION CONTAINS ACETYLCYSTEINE 200,0 mg	200 mgConcentrate solution for dilution for iv infusion	44032944/32.16/0329Approved 23 January 2015	Registered	Not determined	PI PIL
Muco-go 200 effervescent tablets EACH TABLET CONTAINS ACETYLCYSTEINE 200,0 mg	200Effervescent tablets	44092544/10.1/0925	Registered	Not determined	None
Mucatak 200 effervescent tablets EACH TABLET CONTAINS ACETYLCYSTEINE 200,0 mg	200Effervescent tablets	44092744/10.1/0927	Registered	Not determined	None
Acc 600	600 mgEffervescent tablets	45022945/10.3/0229Approved 28 March 2025	Registered	Not determined	PI PIL
Mucofizz 200	200 mgWhite to off white round, flat tablets.	46038446/10.3/0384Approved 14 January 2025	Registered	S1	PI PIL
Acc on the go Each Sachet contains: Acetylcystene 600,0 mg	Not listed	51081651/10.3/0816	Registered	Not determined	None
Tussmuco EACH TABLET CONTAINS ACETYLCYSTEINE 200,0 mg	Not listed	54085454/10.3/0854	Registered	Not determined	None
Gencetyl 200 MG EACH TABLET CONTAINS ACETYLCYSTEINE 200,0 mg	200 mg	56013956/10.3/0139	Registered	Not determined	None
Gencetyl 600 MG EACH TABLET CONTAINS ACETYLCYSTEINE 600,0 mg	600 mg	56014056/10.3/0140	Registered	Not determined	None
Ukastyn 200 MG EACH TABLET CONTAINS ACETYLCYSTEINE 200,0 mg	200 mg	560141.13956/10.3/0141.139	Cancelled	Not determined	None
Ukastyn 600 MG EACH TABLET CONTAINS ACETYLCYSTEINE 600,0 mg	600 mg	560142.14056/10.3/0142.140	Cancelled	Not determined	None
Rocylteine 200 MG EACH TABLET CONTAINS ACETYLCYSTEINE 200,0 mg	200 mg	560143.13956/10.3/0143.139	Registered	Not determined	None
Rocylteine 600 MG EACH TABLET CONTAINS ACETYLCYSTEINE 600,0 mg	600 mg	560144.14056/10.3/0144.140	Registered	Not determined	None
Mucoloc EACH TABLET CONTAINS ACETYLCYSTEINE 600,0 mg	Not listed	57036257/10.3/0362	Registered	Not determined	None
Amuco 600 MG granules EACH SACHET CONTAINS: ACETYLCYSTEINE 600,0 mg	600 mgGranules	57058657/10.3/0586	Registered	Not determined	None
Acetylcysteine 600 MG austell granules EACH SACHET CONTAINS: ACETYLCYSTEINE 600,0 mg	600 mgGranules	570587.58657/10.3/0587.586	Registered	Not determined	None
Acetylcysteine 600 MG camox granules EACH SACHET CONTAINS: ACETYLCYSTEINE 600,0 mg	600 mgGranules	570588.58657/10.3/0588.586	Registered	Not determined	None
Corenza muco 200 EACH TABLET CONTAINS: ACETYLCYSTEINE 200,0 mg	200Effervescent tablet.	57086357/10.3/0863Approved 18 September 2025	Registered	S1	PI PIL
Corenza muco 600 EACH TABLET CONTAINS: ACETYLCYSTEINE 600,0 mg	600Effervescent tablet.	57086457/10.3/0864Approved 18 September 2025	Registered	S1	PI PIL
Acetylcysteine 200 adco EACH TABLET CONTAINS: ACETYLCYSTEINE 200,0 mg	200Effervescent tablet.	570865.86357/10.3/0865.863Approved 18 September 2025	Registered	S1	PI PIL
Acetylcysteine 600 adco EACH TABLET CONTAINS: ACETYLCYSTEINE 600,0 mg	600Effervescent tablet.	570866.86457/10.3/0866.864Approved 18 September 2025	Registered	S1	PI PIL
Flemkleer 200 EACH TABLET CONTAINS ACETYLCYSTEINE 200,0 mg	200	58018658/10.2.2/0186	Registered	Not determined	None
Acetylcysteine 200 clicks EACH TABLET CONTAINS ACETYLCYSTEINE 200,0 mg	200	58022258/10.3/0222	Registered	Not determined	None
Acetylcysteine 600 sandoz EACH TABLET CONTAINS ACETYLCYSTEINE 600,0 mg	600	59006059/10.3/0060	Registered	Not determined	None
Acetylcysteine 600 hexal EACH TABLET CONTAINS ACETYLCYSTEINE 600,0 mg	600	590061.06059/10.3/0061.060	Registered	Not determined	None
Tussmuco 600 EACH TABLET CONTAINS: ACETYLCYSTEINE 600,0 mg	600 mgEffervescent tablets	59010459/10.3/0104Approved 25 November 2025	Registered	S1	PI PIL
Acc 600 hot EACH SACHET CONTAINS: ACETYLCYSTEINE 600,0 mg	600	59040659/10.3/0406	Registered	Not determined	None
Parvolex EACH 5,0 ml CONTAINS ACETYLCYSTEINE 200,0 mg	200mg / 10mlInjection	NX0156NX/34/156Approved 19 July 1984	Registered	S2	PI
Mucolit 100 EACH SACHET CONTAINS ACETYLCYSTEINE 100 MG	100	W0247W/10.2.2/247	Cancelled	Not determined	None

Regulatory status

Where S3 sits on the scale

S0S1S2S3S4S5S6S7S8

Needs a doctor's prescription, dispensed by a pharmacist.

Schedule 3 medicines can only be sold on a prescription from an authorised prescriber, such as a doctor or dentist. A pharmacist dispenses the medicine once they have the written prescription, or a verbal instruction from a prescriber they know. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S3, read from the product's PI-PIL leaflet.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Acetylcysteine

S3: Acetylcysteine
- when intended for injection or for the management of paracetamol overdosage;
- except when used as a mucolytic in acute respiratory conditions for a maximum treatment period of 14 days. (S1)
Consolidated Schedules 06 July 2026, lines 3109 to 3114
S1: Acetylcysteine
- when used as a mucolytic in acute respiratory conditions for a maximum treatment period of 14 days;
- except when intended for injection or for the management of paracetamol overdosage. (S3)
Consolidated Schedules 06 July 2026, lines 102 to 106

Pharmacological class: Anti-gout preparations. (class 3.3)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

Aloribex 300, Ipharma (Pty) Ltd is scheduled S3 in its official SAHPRA documents, read with 90% confidence.

Professional information (PI)For healthcare professionalsAloribex 300, Ipharma (Pty) Ltd Patient information leaflet (PIL)For patients and carersAcc 200, Sandoz South Africa (Pty) Ltd

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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