Cimetidine

Sold as Secadine, Hexamet, Cymi, A-lennon cimetidine, Cimlok, Cimetidine adco, Aci-med, Norton- cimetidine, Norton cimetidine, Cimetidine arya, Garec-cimetidine, Lenamet otc, Ulcim, Bio-cimetidine, Pharma-q cimetidine, Mexiena, Tagamet, Tagamet iv, Lenamet, Dyspamet chewtab, Dyspamet, Lenamet 2oo mg/, Ulmet, Adco-cimetidine, Sandoz cimetidine

S3Read from the PI-PIL document and verified

C₁₀H₁₆N₆S252.34 g/mol

1-Cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine

Drag to rotate. Structure from PubChem CID 2756.

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Registration

Applicants: 14
Registrations: 45
Schedule source: SAHPRA documentation

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Biotech Laboratories (Pty) Ltd	Secadine, Bio-cimetidine, Mexiena	200 mg, 400 mg	270102, 270103, 310679, 310680, 560740	S3S2 to S3 by pack	PI PIL
Viatris South Africa (Pty) Ltd	Secadine	syrup	270104	Not determined	None
Sandoz South Africa (Pty) LtdCancelled	Hexamet	400	270208	Not determined	None
Pharmacare limited û woodmead15 of 17 cancelled	Cymi, A-lennon cimetidine, Lenamet otc, Ulcim, Tagamet, Tagamet iv, Lenamet, Dyspamet chewtab, Dyspamet, Lenamet 2oo mg/	200 mg, 400 mg, injection, 2 ml, 200 mg/5 ml, 800 mg	280188, 280189, 300412, 300492, J0307, J0308, J0309, P0173, S0328, T0022, U0066, U0067, W0227, W0307, W0308, Y0032, Z0176	Not determined	None
Pharma-q Holdings (Pty) Ltd	Cimlok, Pharma-q cimetidine	200 mg, 200 mg/2 ml, 400 mg	290193, 290194, 320196	Not determined	None
Adcock Ingram Critical Care (Pty) Ltd	Cimetidine adco	100 mg/ml	290214	Not determined	None
Triomed (Pty) Ltd	Aci-med	400 mg	290445	Not determined	None
Medicine Developers International (Pty) Ltd	Norton- cimetidine, Norton cimetidine	200, 400, 800	290677, 290678, 290679	Not determined	None
Arya Pharma (Pty) Ltd1 of 3 cancelled	Cimetidine arya	200, 400, 800	300046, 300047, 300059	Not determined	None
Garec (Pty) LtdCancelled	Garec-cimetidine	200, 400 mg, 800	300102, 300103, 300115	Not determined	None
Merck Generics Rsa (Pty) Ltd	Ulmet	200, 400	Y0405, Y0406	Not determined	None
Adcock ingram limited1 of 3 cancelled	Adco-cimetidine	200 mg, 400 mg, 800 mg	Y0426, Y0427, Y0428	Not determined	None
Quatromed limited	Ulcim	400 mg	Z0177	Not determined	None
Dezzo Trading 392 (Pty) Ltd	Sandoz cimetidine	400	Z0350	Not determined	None

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Secadine tablets 200 MG EACH TABLET CONTAINS :CIMETIDINE 200 mg	200 mgTablets	27010227/11.4.3/0102	Registered	Not determined	None
Secadine tablets 400 MG EACH TABLET CONTAINS :CIMETIDINE 400,0 mg	400 mgTablets	27010327/11.4.3/0103	Registered	Not determined	None
Secadine syrup* EACH 5 ml SYRUP CONTAINS CIMETIDINE HYDROCHLORIDE EQUIVALENT TO CIMETIDINE 200 mg	Syrup	27010427/11.4.3/0104	Registered	Not determined	None
Hexamet 400 EACH TABLET CONTAINS CIMETIDINE 400 mg	400	27020827/11.4.3/0208	Cancelled	Not determined	None
Cymi - 200 EACH TABLET CONTAINS CIMETIDINE 200 MG	- 200	28018828/11.4.3/0188	Cancelled	Not determined	None
A-lennon cimetidine 400 MG tablets EACH TABLET CONTAINS CIMETIDINE 400 MG	400 mgTablets	28018928/11.4.3/0189	Cancelled	Not determined	None
Cimlok 200 MG EACH TABLET CONTAINS CIMETIDINE 200 MG	200 mg	29019329/11.4.3/0193	Registered	Not determined	None
Cimlok 400 MG EACH TABLET CONTAINS CIMETIDINE 400,0 mg	400 mg	29019429/11.4.3/0194	Registered	Not determined	None
Cimetidine adco 100 mg/ml EACH 2 ml SOLUTION CONTAINS CIMETIDINE 200 mg	100 mg/ml	29021429/11.4.3/0214	Registered	Not determined	None
Aci-med 400 MG tablets EACH TABLET CONTAINS CIMETIDINE 400 mg	400 mgTablets	29044529/11.4.3/0445	Registered	Not determined	None
Norton- cimetidine 200 EACH TABLET CONTAINS CIMETIDINE 200 mg	200	29067729/11.4.3/0677	Registered	Not determined	None
Norton cimetidine 400 EACH TABLET CONTAINS CIMETIDINE 400 MG	400	29067829/11.4.3/0678	Registered	Not determined	None
Norton cimetidine 800 EACH TABLET CONTAINS CIMETIDINE 800 mg	800	29067929/11.4.3/0679	Registered	Not determined	None
Cimetidine 200 arya EACH TABLET CONTAINS CIMETIDINE 200 mg	200	30004630/11.4.3/0046	Registered	Not determined	None
Cimetidine 400 arya EACH TABLET CONTAINS CIMETIDINE 400 mg	400	30004730/11.4.3/0047	Registered	Not determined	None
Cimetidine 800 arya TABLET CIMETIDINE 800 MG	800	30005930/11.4.3/0059	Cancelled	Not determined	None
Garec-cimetidine 200 EACH TABLET CONTAINS CIMETIDINE 200 mg	200	30010230/11.4.3/0102	Cancelled	Not determined	None
Garec-cimetidine 400 MG EACH TABLET CONTAINS CIMETIDINE 400 mg	400 mg	30010330/11.4.3/0103	Cancelled	Not determined	None
Garec-cimetidine 800 EACH TABLET CONTAINS CIMETIDINE 800 mg	800	30011530/11.4.3/0115	Cancelled	Not determined	None
Lenamet otc EACH TABLET CONTAINS CIMETIDINE 200 mg	Not listed	30041230/11.4.3/0412	Registered	Not determined	None
Ulcim injection EACH 2 ml SOLUTION CONTAINS CIMETIDINE 200 mg	Injection	30049230/11.4.3/0492	Cancelled	Not determined	None
Bio-cimetidine 200 EACH TABLET CONTAINS CIMETIDINE 200,0 mg	200Film-coated tablets	31067931/11.4.3/0679Approved 28 March 2024	Registered	S3	PI PIL
Bio-cimetidine 400 EACH TABLET CONTAINS CIMETIDINE 400,0 mg	400Film-coated tablets	31068031/11.4.3/0680Approved 28 March 2024	Registered	S3	PI PIL
Pharma-q cimetidine injection 200 mg/2 ML EACH 2,0 ml AMPOULE CONTAINS CIMETIDINE 200,0 mg	200 mg/2 mlInjection	32019632/11.4.3/0196	Registered	Not determined	None
Mexiena EACH TABLET CONTAINS CIMETIDINE 200,0 mg	200 mgFilm-coated tablets	56074056/11.4.3/0740Approved 20 August 2024	Registered	S2	PI PIL
Tagamet 200 EACH TABLET CONTAINS CIMETIDINE 200 mg	200	J0307J/11.4.3/307	Cancelled	Not determined	None
Tagamet syrup 200 mg/5 ML EACH 5 mL SYRUP CONTAINS CIMETIDINE HYDROCHLORIDE EQUIVALENT TO CIMETIDINE 200 mg	200 mg/5 mlSyrup	J0308J/11.4.3/308	Cancelled	Not determined	None
Tagamet ampoules 200 MG EACH 2 ml SOLUTION CONTAINS CIMETIDINE 200 mg	200 mgAmpoules	J0309J/11.4.3/309	Cancelled	Not determined	None
Tagamet tablets 400 MG EACH TABLET CONTAINS CIMETIDINE 400 mg	400 mgTablets	P0173P/11.4.3/173	Cancelled	Not determined	None
Tagamet iv 400 EACH 100,0 ml SOLUTION CONTAINS CIMETIDINE 400,0mg	400	S0328S/11.4.3/328	Cancelled	Not determined	None
Tagamet tablets 800 MG EACH TABLET CONTAINS CIMETIDINE 800,0 mg	800 mgTablets	T0022T/11.4.3/22	Cancelled	Not determined	None
Lenamet 200 EACH TABLET CONTAINS CIMETIDINE 200 MG	200	U0066U/11.4.3/66	Cancelled	Not determined	None
Lenamet-400 EACH TABLET CONTAINS CIMETIDINE 400 MG	400	U0067U/11.4.3/67	Cancelled	Not determined	None
Lenamet - 800 EACH TABLET CONTAINS CIMETIDINE 800 mg	- 800	W0227W/11.4.3/227	Cancelled	Not determined	None
Dyspamet chewtab tablets 200 MG EACH TABLET CONTAINS CIMETIDINE 200 mg	200 mgTablets	W0307W/11.4.3/307	Cancelled	Not determined	None
Dyspamet suspension 200 mg/5 ML EACH 5 ml SUSPENSION CONTAINS CIMETIDINE 200 mg	200 mg/5 mlSuspension	W0308W/11.4.3/308	Cancelled	Not determined	None
Lenamet injection 2oo mg/2 ML EACH 2 ml AMPOULE CONTAINS CIMETIDINE 200 mg	2 mlInjection	Y0032Y/11.4.3/32	Registered	Not determined	None
Ulmet 200 EACH TABLET CONTAINS CIMETIDINE 200 mg	200	Y0405Y/11.4.3/405	Registered	Not determined	None
Ulmet 400 * EACH TABLET CONTAINS CIMETIDINE 400 mg	400	Y0406Y/11.4.3/406	Registered	Not determined	None
Adco-cimetidine 200 MG EACH TABLET CONTAINS CIMETIDINE 200 mg	200 mg	Y0426Y/11.4.3/426	Registered	Not determined	None
Adco-cimetidine 400 MG EACH TABLET CONTAINS CIMETIDINE 400 mg	400 mg	Y0427Y/11.4.3/427	Registered	Not determined	None
Adco-cimetidine 800 MG EACH TABLET CONTAINS CIMETIDINE 800 MG	800 mg	Y0428Y/11.4.3/428	Cancelled	Not determined	None
Ulcim 200 MG EACH TABLET CONTAINS CIMETIDINE 200 mg	200 mg	Z0176Z/11.4.3/176	Cancelled	Not determined	None
Ulcim 400 MG EACH TABLET CONTAINS CIMETIDINE 400 mg	400 mg	Z0177Z/11.4.3/177	Registered	Not determined	None
Sandoz cimetidine 400 EACH TABLET CONTAINS CIMETIDINE 400,0 mg	400	Z0350Z/11.4.3/350	Registered	Not determined	None

Regulatory status

Where S3 sits on the scale

S0S1S2S3S4S5S6S7S8

Needs a doctor's prescription, dispensed by a pharmacist.

Schedule 3 medicines can only be sold on a prescription from an authorised prescriber, such as a doctor or dentist. A pharmacist dispenses the medicine once they have the written prescription, or a verbal instruction from a prescriber they know. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S3, read from the product's PI-PIL leaflet.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Cimetidine

S3: Cimetidine
- except when intended for the short-term symptomatic relief of heartburn, dyspepsia and hyperacidity, subject to a maximum unit dose of 200 milligrams, a maximum daily dose (per 24 hours) of 800 milligrams and a maximum treatment period of 2 weeks. (S2)
Consolidated Schedules 06 July 2026, lines 3332 to 3334
S2: Cimetidine
- when intended for the short-term symptomatic relief of heartburn, dyspepsia and hyperacidity, subject to a maximum unit dose of 200 milligrams, a maximum daily dose of 800 milligrams and a maximum treatment period of 2 weeks. (S3)
Consolidated Schedules 06 July 2026, lines 1740 to 1742

Pharmacological class: Other. (class 11.4.3)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

Bio-cimetidine 200, Biotech Laboratories (Pty) Ltd is scheduled S3 in its official SAHPRA documents, read with 90% confidence.

Professional information (PI)For healthcare professionalsBio-cimetidine 200, Biotech Laboratories (Pty) Ltd Patient information leaflet (PIL)For patients and carersBio-cimetidine 200, Biotech Laboratories (Pty) Ltd

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

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