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Cyproheptadine

Schedule 2 to 5, conditions apply
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C21H21N287.40 g/mol

1-Methyl-4-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylidene)piperidine

Drag to rotate. Structure from PubChem CID 2913.

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Listing

Schedules
Schedule 2 to 5, conditions apply
Source
Consolidated Schedules 06 July 2026

Registered medicines

2 registered products listed

Counted through the register's ingredient index, which does not reach every record.

Registered products
NameBrandsDosagesApplicantsRegistrationsSchedule
Cyproheptadine hydrochloride cyproheptadineCipla-actinNot statedCipla Medpro (Pty) Ltd360072S2 to S5conditions apply
CyproheptadineZyactin, Cyproheptadine zydus, Actincypro, +1 more4 mg, syrup4 applicants6 registrationsS2

Regulatory status

Where S2 to S5 sits on the scale

Depends on which listing applies

At the least restrictive, Schedule 2: a pharmacist can sell it directly, without a prescription. At the most restrictive, Schedule 5: prescription-only, with tighter controls on repeats. The listings below say which applies to which form, strength or pack size.

Schedule S2 to S5, as the Consolidated Schedules list it.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it.

Consolidated Schedules listings for Cyproheptadine

  • S5: Cyproheptadine

    • except when indicated for allergic rhinitis or antipruritic use.

    Consolidated Schedules 06 July 2026, line 9349

  • S2: Cyproheptadine

    • when indicated for allergic rhinitis or antipruritic use.

    Consolidated Schedules 06 July 2026, line 1789

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

Research articles

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