Carbocisteine

Sold as Acuphlem, Mucoflem, Merck-carbocisteine, Dynaphlem, Mucodyne, Betaphlem, Mucoless, Mucoless s, Flutex mucous cough, Mucospect, Bronchette, Dino-carb, Corbar m, Lessmusec, Carbospect, Ilivicaps, Mucokleer, Ilvispect, Co-flem, Mucosolv, Mucospect ped, Carbocysteine bliss, Dischem mucolytic, Mucolinct, Flusin mucous cough, Gsa-carbocisteine, Medphlem, Mucosol, Novaflem, Mucopan, Flemgo

C₅H₉NO₄S179.20 g/mol

(2R)-2-Amino-3-(carboxymethylsulfanyl)propanoic acid

Drag to rotate. Structure from PubChem CID 193653.

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Registration

Applicants: 19
Registrations: 35
Schedule source: Consolidated Schedules 06 July 2026

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Resmed healthcare	Acuphlem	Not stated	270010	S2	None
Viatris South Africa (Pty) Ltd	Mucoflem	capsules	270179	S2	None
Merck Generics Rsa (Pty) Ltd	Merck-carbocisteine	syrup	270180	S2	None
Innovata pharmaceuticals	Mucoflem	Not stated	270230	S2	None
Adcock ingram limitedCancelled	Dynaphlem, Mucodyne, Corbar m, Mucolinct, Gsa-carbocisteine, Mucosol, Mucopan	syrup	270331, 270395, P0242, X0172, X0283, Y0322, Z0244	S2	None
Unimed Healthcare (Pty) Ltd	Betaphlem	capsules	280232	S2	None
Johnson & Johnson (Pty) Ltd û East London1 of 2 cancelled	Mucoless, Mucoless s	Not stated	280327, 280328	S2	None
Pharmacare limited û woodmead2 of 8 cancelled	Flutex mucous cough, Mucospect, Bronchette, Co-flem, Mucospect ped, Dischem mucolytic, Flusin mucous cough	syrup, capsules	290156, L0318, L0320, P0186, V0291, W0216, X0159, X0184	S2	None
FDC SA (Pty) Ltd	Dino-carb	syrup	M0536	S2	None
Ranbaxy Pharmaceutical (Pty) LtdCertificate held by Ranbaxy Pharmaceuticals (Pty) Ltd	Betaphlem	5 ml	S0146	S2	PI PIL
Brunel Laboratoria (Pty) Ltd	Lessmusec	375 mg	T0227	S2	PI PIL
The Premier Pharmaceutical Co LtdCancelled	Carbospect	Not stated	U0219	S2	None
Lebasi Pharmaceuticals (Pty) Ltd1 of 2 cancelled	Ilivicaps, Mucokleer	Not stated	V0234, V0234	S2	None
Procter & Gamble South Africa Trading (Pty) LtdCancelled	Ilvispect	Not stated	V0235	S2	None
Cipla Medpro (Pty) LtdCertificate held by Cipla Medpro (Pty) Ltd.	Mucosolv	375 mg, syrup	W0057, W0324	S2	PI PIL
Gulf Drug Company (Pty) Ltd	Carbocysteine bliss	Not stated	X0045	S2	None
Medpro Pharmaceutica (Pty) Ltd	Medphlem	Not stated	X0339	S2	None
Medicine Developers International (Pty) Ltd	Novaflem	Not stated	Z0023	S2	None
Alliance Pharma (Pty) Ltd	Flemgo	Not stated	Z0330	S2	None

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Acuphlem EACH 5 ml SYRUP CONTAINS CARBOCISTEINE 250 mg	Not listed	27001027/10.2.2/0010	Registered	S2	None
Mucoflem capsules EACH CAPSULE CONTAINS CARBOCISTEINE 375 mg	Capsules	27017927/10.1/0179	Registered	S2	None
Merck-carbocisteine syrup EACH 5 ml SYRUP CONTAINS CARBOCISTEINE 250 mg	Syrup	27018027/10.1/0180	Registered	S2	None
Mucoflem EACH 5 ml SYRUP CONTAINS CARBOCISTEINE 250 mg	Not listed	27023027/10.2.2/0230	Registered	S2	None
Dynaphlem EACH 5 ml SYRUP CONTAINS CARBOCISTEINE 250 mg	Not listed	27033127/10.2.2/0331	Cancelled	S2	None
Mucodyne EACH 5 ml SYRUP CONTAINS CARBOCISTEINE 250 mg	Not listed	27039527/10.2.2/0395	Cancelled	S2	None
Betaphlem capsules* EACH CAPSULE CONTAINS CARBOCISTEINE 375 mg	Capsules	28023228/10.1/0232	Registered	S2	None
Mucoless EACH CAPSULE CONTAINS CARBOCISTEINE 375 mg	Not listed	28032728/10.1/0327	Registered	S2	None
Mucoless s EACH 5 ml SYRUP CONTAINS CARBOCISTEINE 250,0 mg	Not listed	28032828/10.1/0328	Cancelled	S2	None
Flutex mucous cough EACH 5,0 ml SYRUP CONTAINS CARBOCISTEINE 250,0 mg	Not listed	29015629/10.2.2/0156	Registered	S2	None
Mucospect syrup EACH 5 ML SYRUP CONTAINS CARBOCISTEINE 250 mg	Syrup	L0318L/10.1/318	Registered	S2	None
Bronchette syrup EACH 5 ml CONTAINS CARBOCISTEINE 250 mg	Syrup	L0320L/10.1/320	Cancelled	S2	None
Dino-carb syrup EACH 5 ml SYRUP CONTAINS CARBOCISTEINE 250 mg	Syrup	M0536M/10.2.2/536	Registered	S2	None
Mucospect capsules EACH CAPSULE CONTAINS CARBOCISTEINE 375 mg	Capsules	P0186P/10.1/186	Registered	S2	None
Corbar m EACH 5 ml SYRUP CONTAINS CARBOCISTEINE 250 mg	Not listed	P0242P/10.2.2/242	Cancelled	S2	None
Betaphlem syrup EACH 5,0 ml SYRUP CONTAINS CARBOCISTEINE 250,0 mg	5 mlSyrup	S0146S/10.2.2/146Approved 31 August 2022	Registered	S2	PI PIL
Lessmusec EACH CAPSULE CONTAINS CARBOCISTEINE 375 mg	375 mgCapsules	T0227T/10.2.2/227Approved 30 March 2023	Registered	S2	PI PIL
Carbospect* EACH 5 ml SYRUP CONTAINS CARBOCISTEINE 250 mg	Not listed	U0219U/10.2.2/219	Cancelled	S2	None
Ilivicaps EACH CAPSULE CONTAINS CARBOCISTEINE 375 mg	Not listed	V0234V/10.1/234	Cancelled	S2	None
Mucokleer EACH CAPSULE CONTAINS CARBOCISTEINE 375 mg	Not listed	V0234V/10.1/234	Registered	S2	None
Ilvispect EACH 5 ml SYRUP CONTAINS CARBOCISTEINE 250 mg	Not listed	V0235V/10.1/235	Cancelled	S2	None
Co-flem EACH 5 ml SYRUP CONTAINS CARBOCISTEINE 250 mg	Not listed	V0291V/10.2.2/291	Registered	S2	None
Mucosolv capsules EACH CAPSULE CONTAINS CARBOCISTEINE 375 mg	375 mgCapsules	W0057W/10.1/57Approved 11 November 2022	Registered	S2	PI PIL
Mucospect ped EACYH 5 ml SYRUP CONTAINS CARBOCISTEINE 125 mg	Not listed	W0216W/10.1/216	Registered	S2	None
Mucosolv syrup EACH 5 ml CONTAINS CARBOCISTEINE 250 mg	Syrup	W0324W/10.1/324	Registered	S2	None
Carbocysteine bliss EACH 5 ml SYRUP CONTAINS CARBOCISTEINE 250 mg	Not listed	X0045X/10.2.2/45	Registered	S2	None
Dischem mucolytic EACH 5,0 ml SYRUP CONTAINS CARBOCISTEINE 250,0 mg	Not listed	X0159X/10.2.2/159	Cancelled	S2	None
Mucolinct syrup EACH 5 ml SYRUP CONTAINS CARBOCISTEINE 250 mg	Syrup	X0172X/10.2.2/172	Cancelled	S2	None
Flusin mucous cough EACH 5 ml SYRUP CONTAINS CARBOCISTEINE 250 mg	Not listed	X0184X/10.2.2/184	Registered	S2	None
Gsa-carbocisteine EACH 5 ml SYRUP CONTAINS CARBOCISTEINE 250 mg	Not listed	X0283X/10.2.2/283	Cancelled	S2	None
Medphlem* EACH 5 ml SYRUP CONTAINS CARBOCISTEINE 250 mg	Not listed	X0339X/10.2.2/339	Registered	S2	None
Mucosol EACH 5 ml SYRUP CONTAINS CARBOCISTEINE 250 mg	Not listed	Y0322Y/10.2.2/322	Cancelled	S2	None
Novaflem EACH 5 ml SYRUP CONTAINS CARBOCISTEINE 250 mg	Not listed	Z0023Z/10.2.2/23	Registered	S2	None
Mucopan* EACH 5 ml SYRUP CONTAINS CARBOCISTEINE 250 mg	Not listed	Z0244Z/10.1.1/244	Cancelled	S2	None
Flemgo EACH 5 ml SYRUP CONTAINS CARBOCISTEINE 250 mg	Not listed	Z0330Z/10.2.2/330	Registered	S2	None

Regulatory status

Where S2 sits on the scale

S0S1S2S3S4S5S6S7S8

A pharmacist can sell it directly, without a prescription.

Schedule 2 medicines sit behind the pharmacy counter. A pharmacist can decide to sell one of these directly, using their own professional judgement, without a doctor's prescription. It can also be dispensed against a prescription like the higher tiers, in which case the usual repeat limits apply. A child under 12 may only be sold a Schedule 2 substance on a prescription, or on a written order that names the purpose and carries a signature the seller recognises. Even though it cannot be advertised to the public in the ordinary sense, its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S2, matched to the Consolidated Schedules by ingredient, confidence high.

Who may supply: Only a pharmacist, pharmacist intern or supervised pharmacist's assistant may sell it without a prescription. It may otherwise be dispensed by a pharmacist against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Carbocisteine

S2: Carbocisteine
Consolidated Schedules 06 July 2026, line 1717

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

Betaphlem syrup, Ranbaxy Pharmaceutical (Pty) Ltd is scheduled S2 in its official SAHPRA documents, read with 90% confidence.

Professional information (PI)For healthcare professionalsBetaphlem syrup, Ranbaxy Pharmaceutical (Pty) Ltd Patient information leaflet (PIL)For patients and carersBetaphlem syrup, Ranbaxy Pharmaceutical (Pty) Ltd

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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