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Rizatriptan

Schedule 2 to 4, conditions apply
Loading the molecular structure
C15H19N5269.34 g/mol

N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine

Drag to rotate. Structure from PubChem CID 5078.

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Listing

Schedules
Schedule 2 to 4, conditions apply
Source
Consolidated Schedules 06 July 2026

Registered medicines

1 registered product listed

Counted through the register's ingredient index, which does not reach every record.

Registered products
NameBrandsDosagesApplicantsRegistrationsSchedule
RizatriptanMaxalt, Maxalt rpd, Rizagran otc, +12 more5 mg, 5mg, 10 mg, 10mg10 applicants24 registrationsS2 to S4conditions apply

Regulatory status

Where S2 to S4 sits on the scale

Depends on which listing applies

At the least restrictive, Schedule 2: a pharmacist can sell it directly, without a prescription. At the most restrictive, Schedule 4: prescription-only medicine. The listings below say which applies to which form, strength or pack size.

Schedule S2 to S4, as the Consolidated Schedules list it.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Rizatriptan

  • S4: Rizatriptan

    • except when in oral solid dosage forms providing 5 mg or less and presented as packs of no more than 2 oral solid dosage forms, indicated for the acute relief of migraine attacks, with or without aura, in patients previously diagnosed by a medical practitioner and initiated on treatment with rizatriptan (S2)

    Consolidated Schedules 06 July 2026, lines 7826 to 7828

  • S2: Rizatriptan

    • when in oral solid dosage forms providing 5 mg or less and presented as packs of no more than 2 oral solid dosage forms, indicated for the acute relief of migraine attacks, with or without aura, in patients previously diagnosed by a medical practitioner and initiated on treatment with rizatriptan (S4)

    Consolidated Schedules 06 July 2026, lines 2642 to 2644

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

Research articles

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