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S1

Schedule 1 (S1) medicines in South Africa

Sold by a pharmacist, no doctor's prescription needed.

About S1 Drugs

Where S1 sits on the scale

Sold by a pharmacist, no doctor's prescription needed.

Schedule 1 medicines are normally sold by a pharmacist, or by a supervised pharmacist intern or assistant, without a doctor's visit; a veterinarian, or a licensed dispensing doctor, dentist or nurse prescriber, may also supply them. A nurse or other non-doctor prescriber may only prescribe the specific substances the Schedule names for that purpose, and may only dispense them if licensed to do so. A child under 12 may only be sold one of these medicines on a prescription, or on a written order that names the purpose and carries a signature the seller recognises.

Cited: Act s22A(4), s22A(4)(b)

Who may supply

A pharmacist, or a supervised pharmacist intern or assistant; manufacturers and wholesalers supplying people who may lawfully possess it; a veterinarian, who may prescribe, compound or dispense it; a medical practitioner or dentist, who may prescribe it, and may compound or dispense it only if licensed under section 22C(1)(a); a nurse or other registered non-doctor prescriber, who may prescribe only the Scheduled substances the Schedule identifies for that purpose, and dispense them if licensed to do so; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Cited: Act s22A(4)(a)(ii), s22A(4)(a)(iii), s22A(4)(a)(iv), s22A(4)(a)(v)(aa), s22A(6)(r)

Advertising: May be advertised to the public.

Cited: reg 42(1) (General Regulations, 2017)

Labelling: Must show the letter S and the number 1 in a square border, immediately before the product's brand name.

Cited: reg 10(1)(a) (General Regulations, 2017)

What is a Schedule 1 medicine in South Africa?

Sold by a pharmacist, no doctor's prescription needed. Schedule 1 medicines are normally sold by a pharmacist, or by a supervised pharmacist intern or assistant, without a doctor's visit; a veterinarian, or a licensed dispensing doctor, dentist or nurse prescriber, may also supply them. A nurse or other non-doctor prescriber may only prescribe the specific substances the Schedule names for that purpose, and may only dispense them if licensed to do so. A child under 12 may only be sold one of these medicines on a prescription, or on a written order that names the purpose and carries a signature the seller recognises.

Can a pharmacist sell a Schedule 1 medicine without a prescription?

No prescription is needed. A pharmacist, or a supervised pharmacist intern or assistant; manufacturers and wholesalers supplying people who may lawfully possess it; a veterinarian, who may prescribe, compound or dispense it; a medical practitioner or dentist, who may prescribe it, and may compound or dispense it only if licensed under section 22C(1)(a); a nurse or other registered non-doctor prescriber, who may prescribe only the Scheduled substances the Schedule identifies for that purpose, and dispense them if licensed to do so; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

Substances listed under S1

182 listed in the Consolidated Schedules, 80 with a registered medicine.

Registered medicines in S1

Showing 36 of 36 chemicals in schedule S1
Registered products
NameBrandsDosagesApplicantsRegistrationsSchedule
AcetycysteineAcc for200 mgSandoz South Africa (Pty) Ltd550685S1
AcetylcysteinePholtex mucus, Mucofizz, Tussmuco, +2 more200 mg, 600 mg4 applicants8 registrationsS1
AmorolfineLoceryl, Onyban, Amorolfine glenmark, +5 more5 %, 5 % w/v, 5%, 50 mg/1 ml, +1 more7 applicants8 registrationsS1
AmylmetacresolStrepsils numbing2.4 mg / 1.2 mg / 0.6 mgReckitt Benckinser Pharmaceuticals (Pty) Ltd280647S1
Azelaic acidSkinoren, Skinoren acnegel, creamAdcock ingram limited2 registrationsS1
BenzocaineCoryx throat100 mLCipla Medpro (Pty) LtdW0058S1
BenzydamineGesoral, Septolete co15 ml, lozenge, 1.5mg/5mg/ml2 applicants3 registrationsS1
Bile salts CancelledEntozymeNot statedA H Robins Co (SA) (Pty) Ltd*E0926S1
CetirizineAllecet, Acuzyrt, Seasoneze, +2 more1 mL, 10,0 mg, tablets, 10 mg, +1 more5 applicants8 registrationsS1
ClotrimazoleFungistop topical, Fungistop vaginal, Xeraspor t, +2 more1 g, 10 mg, 20mg / 1g3 applicants5 registrationsS1
EthylAdco-ethyl chloridesprayAdcock ingram limitedG2750S1
FexofenadineTelfast, Fexaway, Fastway, +16 more120 mg, 180 mg, suspension, 120mg/180mg16 applicants38 registrationsS1
FluoresceinMinims fluorescein sodium10 mgSoflens (Pty) LtdT86S1
FlurbiprofenStrepsils intensive8.75mgReckitt Benckinser Pharmaceuticals (Pty) Ltd350015S1
Hyoscine butylbromideJuposci5 mgAdcock Ingram Healthcare (Pty) Ltd - Clayville590174S1
Hyoscine-n-butylHyospasmol5 ml, injectionPharmacare limited û woodmead2 registrationsS1
IbuprofenBrufen, Nurofen express, Lenafengranules, 200mg, 200 mg, 6003 applicants5 registrationsS1
KetoprofenFastum2.5 g per 100 gMenarini South Africa (Pty) LtdZ0165S1
LevocetirizineTexamer, Cetorin, Levocetirizine austell, +2 more0,5 mg/ml, 2 mg, 2,5 MG/ 5 ML, 5 mg3 applicants7 registrationsS1
LidocaineEmla5%, 25 mg/ 25 mgPharmacare limited û woodmead2 registrationsS1
MalathionLesodermlotionResmed healthcareT0205S1
MebendazoleRioworm, Adco-wormex, Wormgo, +9 moretablets, suspension, 100 mg, 100mg/ 5ml, +2 more7 applicants22 registrationsS1
MiconazoleDaktarincream, 20mg / 1g2 applicants2 registrationsS1
NicotineNicorette quickmist1 mgJohnson & Johnson (Pty) Ltd û East London500547S1
Ox bileNutrizymNot statedMerck (Pty) LtdE0509S1
OxibendazoleSerohNot statedLogos Agvet (Pty) Ltd83/521S1
OxymetazolineSinarest, Iliadin aloe1 mL, 1,0 ml2 applicants3 registrationsS1
PancreatinCreon, Pankreozym, Combizym10 000, 25 000, 40 0002 applicants6 registrationsS1
ParacetamolPacipayn500 mgAustell Pharmaceuticals (Pty) Ltd561139S1
PhenylephrineRusaine10 mgUnimed Healthcare (Pty) Ltd560060S1
PramoxineAnusol pain reliefointmentMdi Healthcare CCT0065S1
Procaine CancelledGerovital, Procaine in saline, Pulperyl1 %3 applicants3 registrationsS1
Sodium cromoglycateCromobex20 mg/mlIpharma (Pty) Ltd290382S1
TerbinafineTerbane nail10 % w/wSandoz South Africa (Pty) Ltd561092S1
ThiomersalMerthiolate tincture, Micro thiomersalate tinctureNot stated2 applicants2 registrationsS1
XylometazolineZylovin1 mg/mLLamar International (Pty) Ltd510735S1