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Chlorhexidine

Schedule 1, conditions apply
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C22H30Cl2N10505.40 g/mol

(1E)-2-[6-[[Amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine

Drag to rotate. Structure from PubChem CID 9552079.

Background

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Listing

Schedules
Schedule 1, conditions apply
Exceptions reach
Schedule 0
Source
Consolidated Schedules 06 July 2026

Registered medicines

8 registered products listed

Counted through the register's ingredient index, which does not reach every record.

Registered products
NameBrandsDosagesApplicantsRegistrationsSchedule
Benzocaine, chlorhexidine gluconateOrochlor, Coryx throatspray solution, 100 ml2 applicants3 registrationsS1
Chlorhexidine gluconateHexidin obstetric, Hexidin, Hydrex surgiscrub, +19 morecream, 0,2%, 0,5%, 0,5% w/v, +5 more12 applicants24 registrationsS0
ChlorhexidineSabax chlorhexidine p, Hexidin, Aeroceutical sprayband, +4 more0,02 %, 0,05%, 0,05 %, 5 %5 applicants8 registrationsS1conditions apply
Benzydamine, chlorhexidine gluconateAndolex-c rinse, Oranix, Throflam-co, +7 moreoral, 15 ml, 22.5 mg/18 mg, spray5 applicants10 registrationsS1
Chlorhexidine gluconate, lidocaineEndostil6 ml, 11 mlGen-eye (Pty) Ltd2 registrationsS1 to S4conditions apply
0 5 chlorhexidine gluconateFungaleneNot statedResmed healthcareG1884S1conditions apply
Chlorhexidine a, neomycinNaseptinNot statedGlenmark Pharmaceuticals South Africa (Pty) LtdH1371S1 to S4conditions apply
Chlorhexidine gluconate m vMentadent p mouth washNot statedPharmacare limited û woodmeadR0220S1conditions apply

5 more registered products name Chlorhexidine in their active ingredient

Registered products
NameBrandsDosagesApplicantsRegistrationsSchedule
Chlorhexidine gluconate, silver sulfadiazine CancelledBactrazine c, Flamazine cNot statedSmith & Nephew Pharmaceuticals (Pty) Ltd2 registrations
Chlorhexidine gluconate, propyl alcoholBiotaine in alcohol100 mLB Braun Medical (Pty) Ltd330526
Chlorhexidine gluconate, isopropyl alcoholZhloraprep sterile orange, Biotaine2 %2 applicants2 registrations
Chlorhexidine gluconate, industrial, methylated spiritsD-germ100 mlB Braun Medical (Pty) LtdQ0326
Chlorhexidine, isopropyl alcohol perDermoswabNot statedAlliance Pharma (Pty) LtdR0313

Regulatory status

Where S1 sits on the scale

Sold by a pharmacist, no doctor's prescription needed.

Schedule 1 medicines are normally sold by a pharmacist, or by a supervised pharmacist intern or assistant, without a doctor's visit; a veterinarian, or a licensed dispensing doctor, dentist or nurse prescriber, may also supply them. A nurse or other non-doctor prescriber may only prescribe the specific substances the Schedule names for that purpose, and may only dispense them if licensed to do so. A child under 12 may only be sold one of these medicines on a prescription, or on a written order that names the purpose and carries a signature the seller recognises.

Schedule S1, as the Consolidated Schedules list it.

Who may supply: A pharmacist, or a supervised pharmacist intern or assistant; manufacturers and wholesalers supplying people who may lawfully possess it; a veterinarian, who may prescribe, compound or dispense it; a medical practitioner or dentist, who may prescribe it, and may compound or dispense it only if licensed under section 22C(1)(a); a nurse or other registered non-doctor prescriber, who may prescribe only the Scheduled substances the Schedule identifies for that purpose, and dispense them if licensed to do so; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Chlorhexidine

  • S1: Chlorhexidine

    • when intended for human vaginal use.

    Consolidated Schedules 06 July 2026, line 320

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

Research articles

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