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5-Hydroxy Tryptophan

Schedule 1 to 5, conditions apply
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C11H12N2O3220.22 g/mol

2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid

Drag to rotate. Structure from PubChem CID 144.

Background

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Listing

Schedules
Schedule 1 to 5, conditions apply
Exceptions reach
Schedule 0
Source
Consolidated Schedules 06 July 2026

Registered medicines

The ingredient index links no registered medicine to 5-Hydroxy Tryptophan (register of 13 September 2026).

Counted through the register's ingredient index, which does not reach every record.

Regulatory status

Where S1 to S5 sits on the scale

Depends on which listing applies

At the least restrictive, Schedule 1: sold by a pharmacist, no doctor's prescription needed. At the most restrictive, Schedule 5: prescription-only, with tighter controls on repeats. The listings below say which applies to which form, strength or pack size.

Schedule S1 to S5, as the Consolidated Schedules list it.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it.

Consolidated Schedules listings for 5-hydroxy tryptophan

  • S5: 5-Hydroxy Tryptophan

    • except in oral preparations with a maximum daily dose not exceeding 220 mg of 5-Hydroxy tryptophan, alone or in combination with other active pharmaceutical ingredients; (S1)
    • except in oral preparation with a maximum daily dose not exceeding 220 mg of 5-Hydroxy tryptophan alone or in combination with other active pharmaceutical ingredients, with general health claims as a health supplement. (S0)

    Consolidated Schedules 06 July 2026, lines 9476 to 9483

  • S1: 5-Hydroxy Tryptophan

    • in oral preparations with a maximum daily dose not exceeding 220 mg of 5-Hydroxy tryptophan, alone or in combination with other active pharmaceutical ingredients; (S5)
    • except in oral preparation with a maximum daily dose not exceeding 220 mg of 5-Hydroxy alone or in combination with other active pharmaceutical ingredients, with general health claims as a health supplement. (S0)

    Consolidated Schedules 06 July 2026, lines 514 to 521

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

Research articles

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