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Phenylephrine

Schedule 1 to 4, conditions apply
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C9H13NO2167.20 g/mol

3-[(1R)-1-Hydroxy-2-(methylamino)ethyl]phenol

Drag to rotate. Structure from PubChem CID 6041.

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Listing

Schedules
Schedule 1 to 4, conditions apply
Exceptions reach
Schedule 0
Source
Consolidated Schedules 06 July 2026

Registered medicines

38 registered products listed

Counted through the register's ingredient index, which does not reach every record.

Registered products
NameBrandsDosagesApplicantsRegistrationsSchedule
Caffeine, paracetamol, phenylephrineBsp cold and flu, Adco sinal nscapsules2 applicants2 registrationsS1 to S4conditions apply
Paracetamol, phenylephrine, vitamin cMed lemon flu & congestion hot medication with vitamin c, Corenza para-ceffervescent2 applicants2 registrationsS1 to S4conditions apply
Caffeine, chlorpheniramine, paracetamol, phenylephrine, vitamin cSinustat flu, Flustat, Degoran c, +1 morecapsules, 5 mg4 applicants4 registrationsS1 to S4conditions apply
Chlorpheniramine, phenylephrine, phenylpropanolamineBetalix decongestant, Rinex, Rinex diffucaps, +1 more5 ml, syrup3 applicants4 registrationsS1 to S6conditions apply
Mepyramine, phenylephrineEyegene antihistamine eyedropsPharmacare limited û woodmead300338S1 to S4conditions apply
PhenylephrineMinims phenylephrine hydrochloride, Sudafed pe sinus decongestant, Phenylephrine cipla, +20 more0,1 mg/ml, 0.1/ 10mg/ml, 0,25 %, 1 %, +10 more19 applicants28 registrationsS4
Brompheniramine, phenylephrine CancelledDimetapp cold and allergy, Dimetapp paediatric cold & allergyNot statedGlaxosmithkline Consumer Healthcare SA (Pty) Ltd2 registrationsS1 to S4conditions apply
Paracetamol, phenylephrineSinuphen sinus pain, Flutex junior cold and flusyrup2 applicants2 registrationsS1 to S4conditions apply
Dextromethorphan, paracetamol, phenylephrineFlusin day timecapsulesPharmacare limited û woodmead450480S1 to S4conditions apply
Chlorpheniramine, ibuprofen, phenylephrineCorenza with ibuprofen, Grippon fizz with ibuprofeneffervescent tabletsAdcock ingram limited2 registrationsS1 to S4conditions apply
Paracetamol, phenylephrine, sodium citrate CancelledLemsipNot statedReckitt Benckinser Pharmaceuticals (Pty) LtdB0032S1 to S4conditions apply
Ascorbic acid, diphenhydramine, paracetamol, phenylephrine CancelledCold stopNot statedAdcock ingram limitedB0085S1 to S4conditions apply
Show the other 26 registered products
Registered products
NameBrandsDosagesApplicantsRegistrationsSchedule
Chlorpheniramine, phenylephrineDemazin, Asalen paediatric1,25 mg and 2,5 mg,, syrup2 applicants2 registrationsS2
Brompheniramine, phenylephrine, phenylpropanolamineDimetapp extentabs, Dimetapp elixerNot statedPharmacare limited û woodmead2 registrationsS1 to S6conditions apply
Caffeine, chlorpheniramine, paracetamol, phenylephrineDegoran plus, Grippon cold and flu, Histaconcapsules2 applicants3 registrationsS1 to S4conditions apply
Codeine, mepyramine, paracetamol, phenylephrine CancelledSinupaintabletsThe Premier Pharmaceutical Co LtdC0679S1 to S6conditions apply
Caffeine, codeine, paracetamol, pheniramine, phenylephrine CancelledFlupacNot statedThe Premier Pharmaceutical Co LtdC0685S1 to S6conditions apply
Aspirin, caffeine, chlorpheniramine, phenylephrineDristantabletPfizer Laboratories (Pty) LtdC0717S1 to S4conditions apply
Mepyramine, paracetamol, phenylephrineSinu-flutabletsCipla Medpro (Pty) LtdC0739S1 to S4conditions apply
Ascorbic acid, caffeine, chlorpheniramine, paracetamol, phenylephrineGrippon, Dristan cold & flucapsules2 applicants2 registrationsS1 to S4conditions apply
Codeine, diphenhydramine, mepyramine, paracetamol, phenylephrine CancelledAntiflutabletsThe Premier Pharmaceutical Co LtdC0834S1 to S6conditions apply
Chlorpheniramine, paracetamol, phenylephrineDequa-fluNot statedMicro Healthcare (Pty) LtdC0879S1 to S4conditions apply
Atropine, caffeine, chlorpheniramine, paracetamol, phenylephrine, vitamin cColstat300 mgLebasi Pharmaceuticals (Pty) LtdC0955S2
Diphenhydramine, paracetamol, phenylephrine, vitamin cFluendNot statedAscendis Pharma (Pty) LtdC1009S1 to S4conditions apply
Caffeine, mepyramine, paracetamol, phenylephrine CancelledCetamineNot statedThe Premier Pharmaceutical Co LtdD0031S1 to S4conditions apply
Mepyramine, paracetamol, phenylephrine, quinine, vitamin c CancelledCetaminetabletsThe Premier Pharmaceutical Co LtdD0032S1 to S4conditions apply
Dextromethorphan, diphenhydramine, phenylephrine CancelledBenyphedNot statedJohnson & Johnson (Pty) Ltd û East LondonE0198S1 to S4conditions apply
Betamethasone valerate, lidocaine, phenylephrineBetnovate compoundsuppositoriesGlaxosmithkline South Africa (Pty) LimitedE0538S1 to S4conditions apply
Dimethindene, phenylephrineVibrocil-s nasal, Vibrocil-sgel, solution2 applicants2 registrationsS1 to S4conditions apply
Ascorbic acid, atropine, caffeine, chlorpheniramine, paracetamol, phenylephrineFamucaps2 mgBrunel Laboratoria (Pty) LtdG1235S2
Cyclopentolate, phenylephrineCyclomydrilNot statedAlcon Laboratories (SA) (Pty) LtdH1149S1 to S4conditions apply
Phenazone, phenylephrineIkleerNot statedAlliance Pharma (Pty) LtdH1205S1 to S4conditions apply
Boric acid, phenylephrineB.E. EyedropsBeige Pharmaceuticals (Pty) LtdH1223S1 to S4conditions apply
Borax, boric acid, phenylephrine, sodium chlorideEye-gene eye, I-glo eyedropsPharmacare limited û woodmead2 registrationsS1 to S4conditions apply
Hydrocortisone, neomycin, phenylephrine, phenylpropanolamineNasomixinNot statedSanofi-aventis South Africa (Pty) LtdH1422S1 to S6conditions apply
Naphazoline, phenylephrineJacks thick nose, Fenox nasal, Ent nasaldrops, spray3 applicants3 registrationsS1 to S4conditions apply
Pheniramine, phenylephrineDristan nasal mistNot statedPharmacare limited û woodmeadH1495S1 to S4conditions apply
Anhydrous, caffeine, chlorpheniramine, paracetamol, phenylephrine, vitamin c CancelledCepacol coldcapsulesAdcock ingram limitedR0247S1 to S4conditions apply

1 more registered product name Phenylephrine in their active ingredient

Registered products
NameBrandsDosagesApplicantsRegistrationsSchedule
Phenylephrine, pholcodinePholtex plusNot statedInova Pharmaceuticals (Pty) Ltd460711

Regulatory status

Where S1 to S4 sits on the scale

Depends on which listing applies

At the least restrictive, Schedule 1: sold by a pharmacist, no doctor's prescription needed. At the most restrictive, Schedule 4: prescription-only medicine. The listings below say which applies to which form, strength or pack size.

Schedule S1 to S4, as the Consolidated Schedules list it.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Phenylephrine

  • S4: Phenylephrine

    • when intended for injection
    • except ophthalmic preparations containing 0,2 percent or less. (S0)
    • except for oral dosage forms, nasal dosage forms, or ophthalmic dosage forms containing more than 0,2 percent (S1)

    Consolidated Schedules 06 July 2026, lines 7545 to 7552

  • S1: Phenylephrine

    • when intended for oral dosage forms, nasal dosage forms, or ophthalmic dosage forms containing more than 0,2 percent; (S1)
    • except ophthalmic preparations containing 0,2 percent or less; (S0)
    • except when intended for injection. (S4)

    Consolidated Schedules 06 July 2026, lines 1007 to 1014

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

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