Clotrimazole

Sold as Innospore, Clotrimazole vaginal dis-chem, Dis-chem clotrimazole topical, Candizole v, Normospor vaginal, Normospor, Medaspor vaginal, Fungistop topical, *Fungistop vaginal, Mycoban, Medaspor topical, Micomisan, Micomisan vaginal, Innospore topical, Merck-clotrimazole vaginal, Adco-clotrimazole vaginal, Adco-clotrimazole topical, Xeraspor t, Xeraspor v, Gynezol, Clomaderm, Canex t, Canex v, Closcript topical, Closcript vaginal, Canalba, Canalba vaginal, Ascendospor, Ascendospor vaginal, Canesten duopak, Trimaze, Gyno-trimaze vaginal, Glenmark clotrimazole vaginal, Pinaspor t, Pinaspor v, Vari-clotrimazole m/m topical, Candizole vaginal, Cloderma topical, Clofem vaginal, Clofunzo vaginal, Clofunzo topical, Canesten 3vc, Canesten vaginal, Canesten topical, Candizole topical, Canesten vc, Candaspor vaginal, Candaspor, A-por, A-por vaginal, Mycoban vaginal

S1Read from the PI-PIL document and verified

C₂₂H₁₇ClN₂344.80 g/mol

1-[(2-Chlorophenyl)-diphenylmethyl]imidazole

Drag to rotate. Structure from PubChem CID 2812.

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Registration

Applicants: 19
Registrations: 55
Schedule source: SAHPRA documentation

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Innovata pharmaceuticals	Innospore, Innospore topical	cream	270068, 280207	Not determined	None
Phyto Otc Health (Pty) Ltd	Clotrimazole vaginal dis-chem, Dis-chem clotrimazole topical	cream	270125, 270126	Not determined	None
Pharmacare limited û woodmead2 of 10 cancelled	Candizole v, Canalba, Canalba vaginal, Trimaze, Gyno-trimaze vaginal, Candizole vaginal, Candizole topical, A-por, A-por vaginal	cream, tablet, solution	270150, 290129, 290130, 310072, 310073, 380157, P0164, P0312, Z0375, Z0376	Not determined	None
Adcock ingram limitedCancelled	Normospor vaginal, Normospor, Mycoban, Micomisan, Micomisan vaginal, Adco-clotrimazole vaginal, Adco-clotrimazole topical, Mycoban vaginal	cream	270173, 270201, 280056, 280152, 280153, 280311, 280322, Z0379	Not determined	None
Medpro Pharmaceutica (Pty) Ltd1 of 3 cancelled	Medaspor vaginal, Medaspor topical, Pinaspor v	cream	270285, 280119, 330267	Not determined	None
Biotech Laboratories (Pty) LtdCertificate held by Biotech Laboratories (Pty) Ltd.	Fungistop topical, *Fungistop vaginal, Clofunzo vaginal, Clofunzo topical	10 mg	270337, 270338, 590660, 590661	S1	PI PIL
Merck Generics Rsa (Pty) Ltd	Merck-clotrimazole vaginal	Not stated	280208	Not determined	None
FDC SA (Pty) LtdCertificate held by FDC (Pty) Ltd	Xeraspor t, Xeraspor v	1 g, cream	280390, 280391	S1	PI PIL
Gulf Drug Company (Pty) Ltd	Gynezol, Clomaderm	Not stated	280418, 280419	Not determined	None
Shanur Healthcare (Pty) Ltd	Canex t, Ascendospor vaginal	Not stated	280626, 290199	Not determined	None
Ascendis Pharma (Pty) Ltd	Canex v, Ascendospor	Not stated	280627, 290198	Not determined	None
Barrs Pharmaceutical Industries (Pty) Ltd	Closcript topical, Closcript vaginal	Not stated	280629, 280630	Not determined	None
Bayer (Pty) Ltd û IsandoCertificate held by Bayer2 of 7 cancelled	Canesten duopak, Canesten 3vc, Canesten vaginal, Canesten topical, Canesten vc	20mg / 1g, 500mg, 100mg / 10g, tablets, cream, 1, 500mg / 5g	300111, A390589, E0047, E0049, K0187, Q0281, U0205	S1	PI PIL
Glenmark Pharmaceuticals South Africa (Pty) Ltd	Glenmark clotrimazole vaginal	1, 6	320041, 320042	Not determined	None
Cipla Medpro (Pty) LtdCancelled	Pinaspor t	Not stated	330266	Not determined	None
Lebasi Pharmaceuticals (Pty) Ltd	Vari-clotrimazole m/m topical	1 %	360245	Not determined	None
Medicine Developers International (Pty) Ltd	Cloderma topical	cream	380304	Not determined	None
Mothopo pharma chem	Clofem vaginal	cream	380305	Not determined	None
Ranbaxy Pharmaceutical (Pty) LtdCertificate held by Ranbaxy Pharmaceuticals (Pty) Ltd	Candaspor vaginal, Candaspor	10 mg/1g	Y0289, Y0290	Not determined	PI PIL

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Innospore EACH 1 g CREAM CONTAINS CLOTRIMAZOLE 10 mg	Not listed	27006827/20.2.2/0068	Registered	Not determined	None
Clotrimazole vaginal cream dis-chem EACH 100 g CREAM CONTAINS CLOTRIMAZOLE 1 g	Cream	27012527/20.2.2/0125	Registered	Not determined	None
Dis-chem clotrimazole topical cream EACH 1 g CREAM CONTAINS CLOTRIMAZOLE 10 mg	Cream	27012627/20.2.2/0126	Registered	Not determined	None
Candizole v EACH 5 G CREAM CONTAINS CLOTRIMAZOLE 50 MG	Not listed	27015027/20.1.2/0150	Registered	Not determined	None
Normospor vaginal cream EACH 1 g CREAM CONTAINS CLOTRIMAZOLE 10,0 mg	Cream	27017327/20.2.2/0173	Cancelled	Not determined	None
Normospor EACH 1 g CREAM CONTAINS CLOTRIMAZOLE 10,0 mg	Not listed	27020127/20.2.2/201	Cancelled	Not determined	None
Medaspor vaginal cream EACH 1 g CREAM CONTAINS CLOTRIMAZOLE 10 mg	Cream	27028527/20.2.2/0285	Registered	Not determined	None
Fungistop topical EACH 1 g CREAM CONTAINS CLOTRIMAZOLE 10,0 mg	10 mgCream	27033727/20.2.2/0337Approved 29 September 2023	Registered	S1	PI PIL
*Fungistop vaginal EACH 100 g CREAM CONTAINS :CLOTRIMAZOLE 1,0 g	10 mgCream	27033827/20.2.2/0338Approved 17 March 2026	Registered	S1	PI PIL
Mycoban cream EACH 1 g CREAM CONTAINS CLOTRIMAZOLE 10 mg	Cream	28005628/20.2.2/0056	Cancelled	Not determined	None
Medaspor topical EACH 1 g CREAM CONTAINS CLOTRIMAZOLE 10 mg	Not listed	28011928/20.2.2/0119	Registered	Not determined	None
Micomisan EACH 1 g CREAM CONTAINS CLOTRIMAZOLE 10,0 mg	Not listed	28015228/20.2.2/0152	Cancelled	Not determined	None
Micomisan vaginal EACH 1 g CREAM CONTAINS CLOTRIMAZOLE 10,0 mg	Not listed	28015328/20.2.2/0153	Cancelled	Not determined	None
Innospore topical cream EACH 1 g CREAM CONTAINS CLOTRIMAZOLE 10 mg	Cream	28020728/20.2.2/0207	Registered	Not determined	None
Merck-clotrimazole vaginal EACH 1 g CREAM CONTAINS CLOTRIMAZOLE 10 mg	Not listed	28020828/20.2.2/0208	Registered	Not determined	None
Adco-clotrimazole vaginal cream EACH 5 g CREAM CONTAINS CLOTRIMAZOLE 50 mg	Cream	28031128/20.2.2/0311	Cancelled	Not determined	None
Adco-clotrimazole topical cream EACH 5 g CREAM CONTAINS CLOTRIMAZOLE 50 mg	Cream	28032228/20.2.2/322	Cancelled	Not determined	None
Xeraspor t cream EACH 100,0 g CREAM CONTAINS CLOTRIMAZOLE 1,0 g	1 gCream	28039028/20.2.2/0390Approved 21 August 2023	Registered	S1	PI PIL
Xeraspor v cream EACH 100,0 g CREAM CONTAINS CLOTRIMAZOLE 1,0 g	Cream	28039128/20.2.2/0391	Registered	Not determined	None
Gynezol EACH 1 g CREAM CONTAINS CLOTRIMAZOLE 10 mg	Not listed	28041828/20.2.2/0418	Registered	Not determined	None
Clomaderm EACH 1 g CREAM CONTAINS CLOTRIMAZOLE 10 mg	Not listed	28041928/20.2.2/0419	Registered	Not determined	None
Canex t EACH 1,0 g CREAM CONTAINS: CLOTRIMAZOLE 10,0 mg	Not listed	28062628/20.2/0626	Registered	Not determined	None
Canex v EACH 100 G CREAM CONTAINS CLOTRIMAZOLE 1 G	Not listed	28062728/20.2.2/0627	Registered	Not determined	None
Closcript topical EACH 1 g CREAM CONTAINS CLOTRIMAZOLE 10 mg	Not listed	28062928/20.2.2/0629	Registered	Not determined	None
Closcript vaginal EACH 1 g CREAM CONTAINS CLOTRIMAZOLE 10 mg	Not listed	28063028/20.2.2/0630	Registered	Not determined	None
Canalba cream EACH 1 g CREAM CONTAINS CLOTRIMAZOLE 10,0 mg	Cream	29012929/20.2.2/0129	Registered	Not determined	None
Canalba vaginal EACH 1,0 g CREAM CONTAINS CLOTRIMAZOLE 10,0 mg	Not listed	29013029/20.2.2/0130	Registered	Not determined	None
Ascendospor EACH 1 g CREAM CONTAINS CLOTRIMAZOLE 10,0 mg	Not listed	29019829/20.2.2/0198	Registered	Not determined	None
Ascendospor vaginal EACH 1 g CREAM CONTAINS CLOTRIMAZOLE 10 mg	Not listed	29019929/20.2.2/0199	Registered	Not determined	None
Canesten duopak Referred to CLOTRIMAZOLE A	500mg, 100mg / 10gVaginal tablet & cream	30011130/20.2.2/0111Approved 20 March 2018	Registered	Not determined	PI PIL
Trimaze cream EACH 1,0 g CREAM CONTAINS CLOTRIMAZOLE 10,0 mg	Cream	31007231/20.2.2/0072	Registered	Not determined	None
Gyno-trimaze vaginal cream EACH 1 g CREAM CONTAINS CLOTRIMAZOLE 10,0 mg	Cream	31007331/20.2.2/0073	Cancelled	Not determined	None
Glenmark clotrimazole 6 vaginal tablet EACH VAGINAL TABLET CONTAINS CLOTRIMAZOLE 100,0 MG	6Tablet	32004132/20.2.2/0041	Registered	Not determined	None
Glenmark clotrimazole 1 vaginal tablet EACH VAGINAL TABLET CONTAINS CLOTRIMAZOLE 500,0 mg	1Tablet	32004232/20.2.2/0042	Registered	Not determined	None
Pinaspor t EACH 1,0 g CREAM CONTAINS CLOTRIMAZOLE 10,0 mg	Not listed	33026633/20.2.2/0266	Cancelled	Not determined	None
Pinaspor v EACH 1,0 g CREAM CONTAINS CLOTRIMAZOLE 10,0 mg	Not listed	33026733/20.2.2/0267	Cancelled	Not determined	None
Vari-clotrimazole 1 % m/m topical cream EACH 1,0 g CREAM CONTAINS CLOTRIMAZOLE 10,0 mg	1 %Cream	36024536/20.2.2/0245	Registered	Not determined	None
Candizole vaginal tablet EACH TABLET CONTAINS CLOTRIMAZOLE 500,0 mg	Tablet	38015738/20.2.2/0157	Registered	Not determined	None
Cloderma topical cream EACH 1,0 g CREAM CONTAINS CLOTRIMAZOLE 10,0 mg	Cream	38030438/20.2.2/0304	Registered	Not determined	None
Clofem vaginal cream EACH 1,0 g CREAM CONTAINS: CLOTRIMAZOLE 10,0 mg	Cream	38030538/20.2.2/0305	Registered	Not determined	None
Clofunzo vaginal EACH 1,0 g CREAM CONTAINS CLOTRIMAZOLE 10,0 mg	10 mgCream.	59066059/20.2.2/0660Approved 17 March 2026	Registered	S1	PI PIL
Clofunzo topical EACH 1,0 g CREAM CONTAINS CLOTRIMAZOLE 10,0 mg	Not listed	59066159/20.2.2/0661	Registered	Not determined	None
Canesten 3vc EACH 1,0 g CREAM CONTAINS CLOTRIMAZOLE 20,0 mg	20mg / 1gVaginal cream	A390589A39/20.2.2/0589Approved 26 October 2012	Registered	S1	PI PIL
Canesten vaginal tablets EACH TABLET CONTAINS CLOTRIMAZOLE 100 mg	Tablets	E0047E/20.2.2/47	Cancelled	Not determined	None
Canesten topical cream EACH 20 g CREAM CONTAINS CLOTRIMAZOLE 200,0 mg	Cream	E0049E/20.2.2/49	Registered	Not determined	None
Canesten vaginal cream EACH 5 g CONTAINS CLOTRIMAZOLE 50 mg	Cream	K0187K/20.2.2/187	Cancelled	Not determined	None
Candizole topical cream EACH 20 G CREAM CONTAINS CLOTRIMAZOLE 200 MG	Cream	P0164P/20.2.2/164	Registered	Not determined	None
Candizole topical solution EACH 20 ml CONTAINS CLOTRIMAZOLE 200 mg	Solution	P0312P/20.2.2/312	Cancelled	Not determined	None
Canesten 1 vaginal tablet EACH VAGINAL TABLET CONTAINS CLOTRIMAZOLE 50,0 mg	1Tablet	Q0281Q/20.2.2/281	Registered	Not determined	None
Canesten 1 vc EACH 5 g VAGINAL CREAM CONTAINS CLOTRIMAZOLE 0,5 g	500mg / 5gVaginal cream	U0205U/20.2.2/205Approved 12 December 2017	Registered	Not determined	PI PIL
Candaspor vaginal cream EACH 1 g CREAM CONTAINS CLOTRIMAZOLE 10 mg	10 mg/1gCream	Y0289Y/20.2.2/289Approved 13 January 2022	Registered	Not determined	PI PIL
Candaspor cream* EACH 1 g CREAM CONTAINS CLOTRIMAZOLE 10 mg	10 mg/1gCream	Y0290Y/20.2.2/290Approved 31 August 2021	Registered	Not determined	PI PIL
A-por cream EACH 1 g CREAM CONTAINS CLOTRIMAZOLE 10 mg	Cream	Z0375Z/20.2.2/375	Registered	Not determined	None
A-por vaginal EACH 100 g CREAM CONTAINS CLOTRIMAZOLE 1,0 g	Not listed	Z0376Z/20.2.2/376	Registered	Not determined	None
Mycoban vaginal cream EACH 1 g CREAM CONTAINS CLOTRIMAZOLE 10 mg	Cream	Z0379Z/20.2.2/379	Cancelled	Not determined	None

Regulatory status

Where S1 sits on the scale

S0S1S2S3S4S5S6S7S8

Sold by a pharmacist, no doctor's prescription needed.

Schedule 1 medicines are normally sold by a pharmacist, or by a supervised pharmacist intern or assistant, without a doctor's visit; a veterinarian, or a licensed dispensing doctor, dentist or nurse prescriber, may also supply them. A nurse or other non-doctor prescriber may only prescribe the specific substances the Schedule names for that purpose, and may only dispense them if licensed to do so. A child under 12 may only be sold one of these medicines on a prescription, or on a written order that names the purpose and carries a signature the seller recognises.

Schedule S1, read from the product's PI-PIL leaflet.

The Consolidated Schedules list this ingredient up to S4; the leaflet's S1 applies to this product.

Who may supply: A pharmacist, or a supervised pharmacist intern or assistant; manufacturers and wholesalers supplying people who may lawfully possess it; a veterinarian, who may prescribe, compound or dispense it; a medical practitioner or dentist, who may prescribe it, and may compound or dispense it only if licensed under section 22C(1)(a); a nurse or other registered non-doctor prescriber, who may prescribe only the Scheduled substances the Schedule identifies for that purpose, and dispense them if licensed to do so; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Clotrimazole

S4: Clotrimazole
- except when intended for application to the skin (S1) and when intended for human vaginal use, specifically for the treatment of recurrent vaginal candidiasis. (S1)
Consolidated Schedules 06 July 2026, lines 5859 to 5860
S1: Clotrimazole
- when intended for human vaginal use specifically for the treatment of recurrent vaginal candidiasis; (S4) and
- when intended for application to the skin. (S4)
Consolidated Schedules 06 July 2026, lines 330 to 335

Pharmacological class: Fungicides. (class 20.2.2)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

Fungistop topical, Biotech Laboratories (Pty) Ltd is scheduled S1 in its official SAHPRA documents, read with 90% confidence.

Professional information (PI)For healthcare professionalsFungistop topical, Biotech Laboratories (Pty) Ltd Patient information leaflet (PIL)For patients and carersFungistop topical, Biotech Laboratories (Pty) Ltd

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

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