Lidocaine

Sold as Merck-ceftriaxone diluent, Lignocaine-hcl b braun, Versatis, Caloject, Dobisim, Lignocaine, Remicard, Remicaine, Remicaine topical, Remicaine jelly, Lignane, Lignane topical s/c, Lignane p, Lignane with adrenaline, Lidocaine p, Lignocaine HCL fresenius ( ), Xylotox S.E. Plain, Xylotox plain S.E., Xylonor, Lignotox, Xylocaine, Remicane, Peterkaien, Lignocaine hcl-fresenius ( ), Lignocaine HCL ( ) fresenius, Monocid diluent, Locaine

C₁₄H₂₂N₂O234.34 g/mol

2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide

Drag to rotate. Structure from PubChem CID 3676.

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Registration

Applicants: 12
Registrations: 43

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Merck Generics Rsa (Pty) Ltd	Merck-ceftriaxone diluent	Not stated	380332	Not determined	None
B Braun Medical (Pty) Ltd	Lignocaine-hcl b braun	1 % 10 ML, 1 % 20 ML, 1 % 5 ML, 2 % 10 ML, 2 % 20 ML, 2 % 5 ML	410063, 410064, 410065, 410066, A390436, A390437	Not determined	None
Adcock ingram limitedCertificate held by Adcock Ingram Ltd1 of 13 cancelled	Versatis, Remicard, Remicaine, Remicaine topical, Remicaine jelly, Xylotox S.E. Plain, Xylotox plain S.E., Lignotox, Remicane, Locaine	700 mg, ointment, 0,5 %, 1 %, 2 %, 4 % /, 100 g	430382, E0035, G1347, G1348, G1349, G2799, G2803, G2824, G2827, G2828, G2829, G2830, V0007	Not determined	PI PIL
Hetero Drugs South Africa (Pty) Ltd	Caloject, Dobisim	20, 50, 300	530161, 530162, 530163, 530164.161, 530165.162, 530166.163	Not determined	None
Elanco Animal Health (Pty) Ltd	Lignocaine	2 %	83/110	Not determined	None
The Premier Pharmaceutical Co Ltd4 of 5 cancelled	Lignane, Lignane topical s/c, Lignane with adrenaline, Lidocaine p	1 %, 2 %, 2 % 20 ml, 4 %	G2759, G2762, G2763, G2766, G2771	Not determined	None
Scp Pharmaceuticals (Pty) LtdCancelled	Lignane p	Not stated	G2764	Not determined	None
Fresenius Medical Care South Africa (Pty) Ltd	Lignocaine HCL fresenius ( )	1%, 2 %	G2781, G2782	Not determined	None
Er Bernard Pharmaceuticals (Pty) LtdCancelled	Xylonor	spray	G2822	Not determined	None
Astrazeneca Pharmaceuticals (Pty) Ltd	Xylocaine	10 mg/0,1 ml	G2826	Not determined	None
Pharmacare limited û woodmeadCancelled	Peterkaien, Monocid diluent	ointment	K0001, S0179	Not determined	None
Fresenius Kabi Manufacturing SA (Pty) Ltd1 of 4 cancelled	Lignocaine hcl-fresenius ( ), Lignocaine HCL ( ) fresenius	2% 2 ml, 2% 5 ml, 10%, 20%	M0254, M0255, V0319, V0320	Not determined	None

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Merck-ceftriaxone diluent EACH 1,0 ml AMPOULE CONTAINS LIDOCAINE HYDROCHLORIDE 10,0 mg	Not listed	38033238/34/0332	Registered	Not determined	None
Lignocaine-hcl 1 % b braun 10 ML EACH 1,0 ml SOLUTION CONTAINS LIDOCAINE HYDROCHLORIDE 10,0 mg	1 % 10 ML	41006341/4/0063	Registered	Not determined	None
Lignocaine-hcl 1 % b braun 20 ML EACH 1,0 ml SOLUTION CONTAINS LIDOCAINE HYDROCHLORIDE 10,0 mg	1 % 20 ML	41006441/4/0064	Registered	Not determined	None
Lignocaine-hcl 2 % b braun 10 ML EACH 1,0 ml SOLUTION CONTAINS LIDOCAINE HYDROCHLORIDE 20,0 mg	2 % 10 ML	41006541/4/0065	Registered	Not determined	None
Lignocaine-hcl 2 % b braun 20 ML EACH 1,0 ml SOLUTION CONTAINS LIDOCAINE HYDROCHLORIDE 20,0 mg	2 % 20 ML	41006641/4/0066	Registered	Not determined	None
Versatis 5 % EACH PLASTER CONTAINS LIDOCAINE 700,0 mg	700 mgMedicated plaster.	43038243/3.2.3/0382Approved 2 December 2020	Registered	Not determined	PI PIL
Caloject 20 EACH 2,0 ml SOLUTION CONTAINS LIDOCAINE HYDROCHLORIDE 20,0 mg	20	53016153/4/0161	Registered	Not determined	None
Caloject 50 EACH 5,0 ml SOLUTION CONTAINS LIDOCAINE HYDROCHLORIDE 50,0 mg	50	53016253/4/0162	Registered	Not determined	None
Caloject 300 EACH 30,0 ml SOLUTION CONTAINS LIDOCAINE HYDROCHLORIDE 300,0 mg	300	53016353/4/163	Registered	Not determined	None
Dobisim 20 EACH 2,0 ml SOLUTION CONTAINS LIDOCAINE HYDROCHLORIDE 20,0 mg	20	530164.16153/4/0164.161	Registered	Not determined	None
Dobisim 50 EACH 5,0 ml SOLUTION CONTAINS LIDOCAINE HYDROCHLORIDE 50,0 mg	50	530165.16253/4/0165.162	Registered	Not determined	None
Dobisim 300 EACH 30,0 ml SOLUTION CONTAINS LIDOCAINE HYDROCHLORIDE 300,0 mg	300	530166.16353/4/166.163	Registered	Not determined	None
Lignocaine injection 2 % EACH 1 ml SOLUTION CONTAINS LIDOCAINE HYDROCHLORIDE A 0,02 g	2 %Injection	83/110	Old Medicine	Not determined	None
Lignocaine-hcl 1 % b braun 5 ML EACH 1,0 ml SOLUTION CONTAINS LIDOCAINE HYDROCHLORIDE 10,0 mg	1 % 5 ML	A390436A39/4/0436	Registered	Not determined	None
Lignocaine-hcl 2 % b braun 5 ML EACH 1,0 ml SOLUTION CONTAINS LIDOCAINE HYDROCHLORIDE 20,0 mg	2 % 5 ML	A390437A39/4/0437	Registered	Not determined	None
Remicard EACH 1 ml SOLUTION CONTAINS LIDOCAINE HYDROCHLORIDE 100 mg	Not listed	E0035E/6.2/35	Cancelled	Not determined	None
Remicaine ointment 100 G LIDOCAINE A 5,0 G	Ointment	G1347	Old Medicine	Not determined	None
Remicaine 4 % topical solution / spray 100 ML LIDOCAINE HYDROCHLORIDE A 4,0 G	4 % /Solution spray	G1348	Old Medicine	Not determined	None
Remicaine jelly EACH 100 g GEL CONTAINS LIDOCAINE HYDROCHLORIDE A 2,0 g	100 gTopical jelly	G1349Approved 2 December 2020	Old Medicine	Not determined	PI PIL
Lignane 1 % EACH 25 ML VIAL CONTAINS LIDOCAINE HYDROCHLORIDE A 0,25 G	1 %	G2759	Cancelled	Not determined	None
Lignane 2 % EACH 20 ML CONTAINS LIDOCAINE HYDROCHLORIDE A 400 MG	2 %	G2762	Cancelled	Not determined	None
Lignane topical 4 % s/c vials EACH 10 ML SOLUTION CONTAINS LIDOCAINE HYDROCHLORIDE A 400 MG	4 %Vials	G2763	Cancelled	Not determined	None
Lignane p EACH 1,8 ML CARTRIDGE CONTAINS LIDOCAINE HYDROCHLORIDE A 36,0 MG	Not listed	G2764	Cancelled	Not determined	None
Lignane 2 % with adrenaline 20 ML EACH 20 ml CONTAINS LIDOCAINE HYDROCHLORIDE A 0,4 g	2 % 20 ml	G2766	Cancelled	Not determined	None
Lidocaine p EACH 2,2 ML CONTAINS LIDOCAINE HYDROCHLORIDE A 0,044 G	Not listed	G2771	Old Medicine	Not determined	None
Lignocaine HCL fresenius 1% (vials) EACH 1,0 ml SOLUTION CONTAINS LIDOCAINE HYDROCHLORIDE A 10,0 mg	1%(Vials)	G2781	Old Medicine	Not determined	None
Lignocaine HCL fresenius 2 % (vials) EACH 1,0 ml SOLUTION CONTAINS LIDOCAINE HYDROCHLORIDE A 20,0 mg	2 %(Vials)	G2782	Old Medicine	Not determined	None
Xylotox S.E. Plain EACH 2,0 ml SOLUTION CONTAINS :LIDOCAINE HYDROCHLORIDE A 40,0 mg	Not listed	G2799	Old Medicine	Not determined	None
Xylotox 2 % plain S.E. EACH 1 ML CONTAINS :LIDOCAINE HYDROCHLORIDE A = ANHYDROUS 20 mg	2 %	G2803	Old Medicine	Not determined	None
Xylonor spray EACH 100 G CONTAINS LIDOCAINE A 15,0 G	Spray	G2822	Cancelled	Not determined	None
Lignotox EACh 1 ml SOLUTION CONTAINS LIDOCAINE HYDROCHLORIDE A 20 mg	Not listed	G2824	Old Medicine	Not determined	None
Xylocaine 10 mg/0,1 ML EACH DOSE CONTAINS LIDOCAINE A 10 mg	10 mg/0,1 ml	G2826	Old Medicine	Not determined	None
Remicaine 0,5 % EACH 20 ML VIAL CONTAINS LIDOCAINE HYDROCHLORIDE A 100 MG	0,5 %	G2827	Old Medicine	Not determined	None
Remicane 1 % vial EACH ml SOLUTION CONTAINS LIDOCAINE HYDROCHLORIDE A 10,0 mg	1 %Vial	G2828	Old Medicine	Not determined	None
Remicaine 2 % vial EACH ML CONTAINS LIDOCAINE HYDROCHLORIDE A 20 MG	2 %Vial	G2829	Old Medicine	Not determined	None
Remicaine 2 % ampoule EACH 1,0 ml OF SOLUTION CONTIANS LIDOCAINE HYDROCHLORIDE A 20,0 mg	2 %Ampoule	G2830	Old Medicine	Not determined	None
Peterkaien ointment EACH 1 g OINTMENT CONTAINS LIDOCAINE 50 mg	Ointment	K0001K/13.3/1	Cancelled	Not determined	None
Lignocaine hcl-fresenius 2% 2 ML (ampoules) EACH 2 ml AMPOULE CONTAINS LIDOCAINE HYDROCHLORIDE 40 mg	2% 2 ml(Ampoules)	M0254M/4/254	Registered	Not determined	None
Lignocaine HCL 2% 5 ML (ampoules) fresenius EACH 5 ml AMPOULE CONTAINS LIDOCAINE HYDROCHLORIDE 100 mg	2% 5 ml(Ampoules)	M0255M/4/255	Registered	Not determined	None
Monocid diluent EACH 2,5 ml VIAL CONTAINS LIDOCAINE HYDROCHLORIDE 25,0 mg	Not listed	S0179S/34/0179	Cancelled	Not determined	None
Locaine EACH 1 ml SOLUTION CONTAINS LIDOCAINE HYDROCHLORIDE HEMIHYDRATE EQUIVALENT TO 2O mg LIDOCAINE HYDROCHLORIDE	Not listed	V0007V/4/7	Registered	Not determined	None
Lignocaine HCL 10% (ampoules) fresenius EACH 5,0 ml AMPOULE CONTAINS LIDOCAINE HYDROCHLORIDE MONOHYDRATE 500,0 mg	10%(Ampoules)	V0319V/6.2/319	Registered	Not determined	None
Lignocaine hcl-fresenius 20% (ampoules) EACH 5 ml AMPOULE CONTAINS LIDOCAINE HYDROCHLORIDE MONOHYDRATE 1 g	20%(Ampoules)	V0320V/6.2/320	Cancelled	Not determined	None

Regulatory status

This product is still scheduled by law even when this site could not determine which tier it falls under. The label carries the S number in a square border; ask a pharmacist if you need to know its schedule.

Listings for this ingredient that could not be applied to this product

S4: Lidocaine
- when intended for ophthalmic or parenteral use;
- when intended for the treatment of neuropathic pain associated with previous herpes zoster infection;
- except when intended for topical use; (S1)
- except in oral preparations containing 2 percent or less of lidocaine per dosage form. (S1)
Consolidated Schedules 06 July 2026, lines 6923 to 6935
S1: Lidocaine
- when intended for topical use;
- in oral preparations containing 2 percent or less of lidocaine, per dosage unit;
- except when intended for ophthalmic or parenteral use; (S4)
- except when intended for the treatment of neuropathic pain associated with previous herpes zoster infection. (S4)
Consolidated Schedules 06 July 2026, lines 777 to 786

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Professional information (PI)For healthcare professionalsVersatis 5 %, Adcock ingram limited Patient information leaflet (PIL)For patients and carersVersatis 5 %, Adcock ingram limited

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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