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Niacin

Listed in the Consolidated Schedules as “Niacin (Nicotinic Acid, Vitamin B3) and derivatives thereof

Also known as: Nicotinic Acid

Schedule 1 to 4, conditions apply
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C6H5NO2123.11 g/mol

Pyridine-3-carboxylic acid

Drag to rotate. Structure from PubChem CID 938.

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Listing

Schedules
Schedule 1 to 4, conditions apply
Exceptions reach
Schedule 0
Also listed as
Vitamin B3 (Schedule 3), see Niacin
Source
Consolidated Schedules 06 July 2026

Registered medicines

4 registered products listed

Counted through the register's ingredient index, which does not reach every record.

Registered products
NameBrandsDosagesApplicantsRegistrationsSchedule
Nicotinic acidNiaspan, Tempo, Nicotinic acid50MG, 375mg, 500 mg, 750 mg, +3 more2 applicants7 registrationsS1 to S4conditions apply
Caffeine, nicotinic acid, nux vomica CancelledForce xNot statedAstley Laboratories S.A (Pty) LtdG2545S1 to S4conditions apply
Caffeine, nicotinic acid CancelledNo hot blood & bangalala1J L Rosenberg (Pty) Ltd *G2599S1 to S4conditions apply
Adenosine, nicotinic acid, phospholipids, vitamin b6 CancelledLipostabilNot statedRhone-poulenc Rorer SA (Pty) LtdH0656S1 to S4conditions apply

Regulatory status

Where S1 to S4 sits on the scale

Depends on which listing applies

At the least restrictive, Schedule 1: sold by a pharmacist, no doctor's prescription needed. At the most restrictive, Schedule 4: prescription-only medicine. The listings below say which applies to which form, strength or pack size.

Schedule S1 to S4, as the Consolidated Schedules list it.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Niacin

  • S4: Niacin (Nicotinic Acid)

    • when intended for hypercholesterolaemia and for the management of dyslipidaemias; (S0)
    • except in oral preparations or mixtures containing more than 35 mg of Niacin per recommended daily dose alone or in combination with other active pharmaceutical ingredients. (S1)

    Consolidated Schedules 06 July 2026, lines 7247 to 7252

  • S1: Niacin (Nicotinic Acid, Vitamin B3)

    • in oral preparations or mixtures containing more than 35 mg of Niacin per recommended daily dose alone or in combination with other active pharmaceutical ingredients; (S0)
    • except when intended for hypercholesterolaemia and for the management of dyslipidaemias. (S4)

    Consolidated Schedules 06 July 2026, lines 879 to 884

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

Research articles

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