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S6

S6 - Restricted Substance

Restricted substance

About S6 Drugs

Where S6 sits on the scale

Prescription-only, no repeats without a new prescription.

Schedule 6 covers the most tightly controlled ordinary prescription medicines. Every dispensing needs its own new prescription; nothing can be repeated on the same script. When prescribed, the quantity must be written out in both figures and words. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Cited: reg 33(3)(f)(i) (General Regulations, 2017)

Who may supply

A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it.

Cited: Act s22A(5)(b), s22A(5)(c), s22A(5)(d), s22A(5)(e)

Prescription: Requires a prescription from an authorised prescriber.

Repeats: None. A new prescription is required every time; it cannot be repeated on the same script. The prescription must also be presented for dispensing within 30 days of issue, and the whole course of treatment may not exceed 30 consecutive days.

Cited: Act s22A(6)(d), s22A(6)(i), s22A(6)(o)

Advertising: May be advertised only to health professionals, not the public.

Cited: reg 42(2), reg 42(3) (General Regulations, 2017)

Labelling: Must show the letter S and the number 6 in a square border, immediately before the product's brand name.

Cited: reg 10(1)(a) (General Regulations, 2017)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

S6 Scheduled Drugs

Showing 68 of 68 products in schedule S6
Registered products
NameVariantsApplicantNumberSchedule
Butorphanol (Torbugesic)10mgZoetis South Africa (Pty) Ltd16/11.S6
Butorphanol (Dolorex)Not statedIntervet South Africa (Pty) Ltd18-SepS6
D-norpseudoephedrine (Relislim)20 mgLoock Pharmaceuticals (Pty) Ltd290316S6
Cathine (Leanor) CancelledNot statedAcino Pharma (Pty) Ltd290526S6
Remifentanil (Ultiva, Ultiva ( ), Fortiva)1 mg, 2 mg, 5 mgPharmacare limited û woodmead6 registrationsS6
Pentazocine (Pharma-q Pentazocine)30 mg/1 mlAdcock Ingram Critical Care (Pty) Ltd310208S6
Buprenorphine (Subutex Sublingual, Sobrixa, Temgesic, +1 more)0,4 mg, 2,0 mg, 8,0 mg, 1 ml, tabletsAdcock Ingram Critical Care (Pty) Ltd8 registrationsS6
Sufentanil (Pharma-q Sufentanil, Pharma-q Sufentanil Forte)10 ug/2 ml, 50 ug/10 ml, 250 ug/5 mlPharma-q Holdings (Pty) Ltd3 registrationsS6
Methylphenidate (Ralitin, Adaphen)5, 10, 20Triomed (Pty) Ltd4 registrationsS6
Flunitrazepam (Flunitrazepam Biotech)1Arya Pharma (Pty) Ltd350160S6
Methylphenidate (Ritalin La, Ritalin)20, 30, 40, 10Novartis South Africa (Pty) Ltd5 registrationsS6
Methylphenidate (Methylphenidate Hcl Douglas)10 mg.Acino Pharma (Pty) Ltd360234S6
Cathine (Lodenor)dropsAnmarate (Pty) Ltd370006S6
Methylphenidate (Concerta, Neucon)18 mg, 36 mg, 54 mg, 27 mgJanssen Pharmaceutica (Pty) Ltd8 registrationsS6
Buprenorphine (Sovenor, Butrans)5, 10, 20Mundipharma (Pty) Ltd6 registrationsS6
Sufentanil (Mylan Sufentanil)5 ug/ml 2 ml, 5ug/ml 10 mlViatris South Africa (Pty) Ltd2 registrationsS6
Naloxone (Suboxone, Narbup, Sabax Naloxone)2 mg, 8 mg, 0,02 mg/mlAdcock Ingram Critical Care (Pty) Ltd5 registrationsS6
Oxycodone (Oxycontin Prolonged Release, Oxynorm)5 mg, 10 mg, 20 mg, 40 mg, 80 mgMundipharma (Pty) Ltd10 registrationsS6
Hydromorphone (Jurnista) Cancelled8 mg, 16 mg, 32 mg, 64 mg, 4 mgJanssen Pharmaceutica (Pty) Ltd5 registrationsS6
Methadone (Equity-methadone, Epatadone)2 mg / 1 ml, 10 mg/mlEquity Pharmaceutical (Pty) Ltd2 registrationsS6
Remifentanil (Remifentanil Teva) Cancelled1, 2, 5Teva Pharmaceuticals (Pty) Ltd3 registrationsS6
Remifentanil (Mylan Remifentanil)1 mg, 2 mg, 5 mgViatris South Africa (Pty) Ltd3 registrationsS6
Remifentanil (Remifentanil Adco, Remifentanil Adcoc)1 mg, 2 mg, 5 mgAdcock Ingram Critical Care (Pty) Ltd3 registrationsS6
Tapentadol (Palexia, Palexia Sr)50 mg, 75 mg, 100 mg, 150 mg, 200 mg, 250 mgAdcock ingram limited8 registrationsS6
Methylphenidate (Methylphenidate Biotech, Methylphenidate La Biotech, Lintiral)10 mg, 10, 20, 30, 40, 60Biotech Laboratories (Pty) Ltd7 registrationsS6
Oxycodone (Oxycorrel, Oxycorrell Once Daily)5 mg, 10 mg, 20 mg, 40 MG, 80 MGAustell Pharmaceuticals (Pty) Ltd7 registrationsS6
Methylphenidate (Contramyl Xr)18 mg, 27 mg, 36 mg, 54 mgViatris South Africa (Pty) Ltd4 registrationsS6
Methylphenidate (Acerta)18, 27, 36, 54Teva Pharmaceuticals (Pty) Ltd4 registrationsS6
Methylphenidate (Medikinet Mr)20 mgAdcock ingram limited511090S6
Buprenorphine (Sovetrin, Bupremed, Norbutrin)5, 10, 20Trinity Pharma (Pty) Ltd9 registrationsS6
Methylphenidate (Aterocon La)20 mg, 30 mg, 40 mg, 60 mgAustell Pharmaceuticals (Pty) Ltd4 registrationsS6
Methadone (Methadone Adco)10mgAdcock Ingram Critical Care (Pty) Ltd540839S6
Methadone (Rutrex, Lometasan)10 mg, 0,4 mg/mLArya Pharma (Pty) Ltd2 registrationsS6
Morphine (Oramorph)20 mgEurolab (Pty) Ltd550422S6
Methadone (Misyo)10 mg/mlUmsebe healthcare550741S6
Methylphenidate (Neutif) Cancelled18Ranbaxy Pharmaceuticals (Pty) Ltd550816S6
Methylphenidate (Neutif, Satefin, Metheylphenidate Sun) Cancelled27, 36, 54, 18Ranbaxy Pharmaceutical (Pty) Ltd11 registrationsS6
Methylphenidate (Conufen, Mefedinel)54, 18, 27, 36, 10 mgSandoz South Africa (Pty) Ltd5 registrationsS6
Methylphenidate (Phenitab)18, 27, 36, 54Activo Health (Pty) Ltd4 registrationsS6
Methylphenidate (Methylphenidate DRL)18, 27, 36, 54Dr Reddyæs Laboratories (Pty) Ltd4 registrationsS6
Remifentanil (Remifentanil Aspen)5 mgAspen SA Operations (Pty) Ltd570170S6
Methylphenidate (Methycap La)10 mg, 20 mg, 30 mg, 40 mgPharma Dynamics (Pty) Ltd4 registrationsS6
Remifentanil (Remivion)1 mg, 2 mg, 5 mgLamar International (Pty) Ltd3 registrationsS6
Phenylbutazone (Fenylbutazone Phenix)20%Phenix SA (Pty) Ltd83/284S6
Phenylbutazone (Arthridine Nf) CancelledNot statedVirbac Rsa (Pty) Ltd83/654S6
Phenylbutazone (Oralject P Butazone) Cancelled-Rhone-poulenc Animal Health SA (Pty) Ltd83/713S6
Phenylbutazone (Phenylarthrite)Not statedBayer (Pty) Ltd û Isando83/764S6
Phenylbutazone (Equipalazone)Not statedKyron Animal Health (Pty) Ltd83/87S6
Cyclizine a 39 01 morphine (Cyclimorph)10, 15Pharmacare limited û woodmead2 registrationsS6
Methadone (Physeptone)injectionPharmacare limited û woodmeadB0771S6
Codeine, morphine, papaverine (Omnopon-fresenius)1mlFresenius Medical Care South Africa (Pty) LtdB1006S6
Fentanyl (Sublimaze)2ml/10 mlPiramal Critical Care South Africa (Pty) Ltd2 registrationsS6
Oxymorphone (Numorphan)Not statedBoots Pharmaceuticals (Pty) LtdB1560S6
Methylphenidate (Ritalin) Cancelled10mg, 10mg. 20mg. 30mg. 40mgCiba-geigy (Pty) LtdB1611S6
Phendimetrazine (Obex La) CancelledNot statedAdcock ingram limitedC0714S6
Phendimetrazine (Obesan X)Not statedMdi Healthcare CCC0877S6
Diethylpropion (Tenuate Dospan) CancelledtabletsAdcock ingram limitedC0965S6
Methadone (Physeptone) CancelledlinctusAcino Pharma (Pty) LtdG0523S6
Codeine, morphine, papaverine (Omnopon-fresenius)1mlBodene (Pty) Ltd Trading As IntramedK0304S6
Buprenorphine (Temgesic)2 mlReckitt Benckinser Pharmaceuticals (Pty) LtdL0158S6
Cathine (Thinz, Slenz) CancelledNot statedPharmacare limited û woodmead2 registrationsS6
D-norpseudoephedrine (Eetless) CancelledcapsulesAdcock ingram limitedM0169S6
Cathine (Dietene, Appetrol Diet, Slim 'N Trim)capsulesAdcock ingram limited3 registrationsS6
Alfentanil (Rapifen)2 mlPiramal Critical Care South Africa (Pty) LtdQ0327S6
Alfentanil (Rapifen)10 MLJanssen Pharmaceutica (Pty) LtdQ0328S6
Sufentanil (Sufenta, Sufenta Forte)2 ml, 10 ml, 50 µgPiramal Critical Care South Africa (Pty) Ltd3 registrationsS6
Pentazocine (Sosenol)30 mg, 45 mgAdcock ingram limited2 registrationsS6
Pentazocine (Pentazocine Fresenius)30 mg/1 mlFresenius Kabi Manufacturing SA (Pty) LtdW0165S6