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Oxycodone

Also known as: 14-hydroxydihydrocodeinone or dihydrohydroxycodeinone

Schedule 6
Loading the molecular structure
C18H21NO4315.40 g/mol

(4R,4AS,7aR,12bS)-4a-hydroxy-9-methoxy-3-methyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one

Drag to rotate. Structure from PubChem CID 5284603.

Background

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Listing

Schedules
Schedule 6
Source
Consolidated Schedules 06 July 2026

Registered medicines

3 registered products listed

Counted through the register's ingredient index, which does not reach every record.

Registered products
NameBrandsDosagesApplicantsRegistrationsSchedule
Buprenorphine, naloxoneSuboxone, Narbup2 mg, 8 mgAdcock Ingram Critical Care (Pty) Ltd4 registrationsS6
OxycodoneOxycontin prolonged release, Oxynorm, Oxycorrel, +1 more5 mg, 10 mg, 20 mg, 40 mg, +1 more2 applicants17 registrationsS6
Naloxone, oxycodoneTarginact prolonged release, Xonocod xr, Codep xr5 mg/2,5 mg, 5/2,5 mg, 10 mg/5 mg, 10/5 mg, +5 more2 applicants14 registrationsS4 to S6

Regulatory status

Where S6 sits on the scale

Prescription-only, no repeats without a new prescription.

Schedule 6 covers the most tightly controlled ordinary prescription medicines. Every dispensing needs its own new prescription; nothing can be repeated on the same script. When prescribed, the quantity must be written out in both figures and words. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S6, as the Consolidated Schedules list it.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it.

Consolidated Schedules listings for Oxycodone

  • S6: Oxycodone (14-hydroxydihydrocodeinone or dihydrohydroxycodeinone)

    Consolidated Schedules 06 July 2026, line 10363

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

Research articles

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