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Pyrazinamide

Schedule 3 to 4, conditions apply
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C5H5N3O123.11 g/mol

Pyrazine-2-carboxamide

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Background

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Listing

Schedules
Schedule 3 to 4, conditions apply
Source
Consolidated Schedules 06 July 2026

Registered medicines

3 registered products listed

Counted through the register's ingredient index, which does not reach every record.

Registered products
NameBrandsDosagesApplicantsRegistrationsSchedule
Ethambutol, isoniazid, pyrazinamide, rifampicinRifafour e, Rimstar 4-fdc, Koxirip, +3 more75mg, 150mg, 150 mg , 75 mg , 400 mg and 275 mg, 275mg, +2 more6 applicants6 registrationsS4
PyrazinamideMacleods pyrazinamide, Pyrazide, Fams pyrazinamide, +6 more500, tablets8 applicants9 registrationsS3 to S4conditions apply
Isoniazid, pyrazinamide, rifampicinCo-afaris paed, Co-ripyso paed, Co-orizit paed75/50/150Macleods Pharmaceuticals SA (Pty) Ltd3 registrationsS3 to S4conditions apply

Regulatory status

Where S3 to S4 sits on the scale

Depends on which listing applies

At the least restrictive, Schedule 3: needs a doctor's prescription, dispensed by a pharmacist. At the most restrictive, Schedule 4: prescription-only medicine. The listings below say which applies to which form, strength or pack size.

Schedule S3 to S4, as the Consolidated Schedules list it.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Pyrazinamide

  • S4: Pyrazinamide

    Consolidated Schedules 06 July 2026, line 7685

  • S3: Pyrazinamide

    • when intended for oral use.

    Consolidated Schedules 06 July 2026, line 4189

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

Research articles

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