Physostigmine
[(3AR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-methylcarbamate
Drag to rotate. Structure from PubChem CID 5983.
Background
Listing
- Schedules
- Schedule 3 to 4, conditions apply
- Source
- Consolidated Schedules 06 July 2026
Registered medicines
Counted through the register's ingredient index, which does not reach every record.
1 more registered product name Physostigmine in their active ingredient
| Name | Brands | Dosages | Applicants | Registrations | Schedule |
|---|---|---|---|---|---|
| Physostigmine salicylate Cancelled | Antilirium | Not stated | Tedro Products (Pty) Ltd * | J0144 |
Regulatory status
Where S3 to S4 sits on the scale
Depends on which listing applies
At the least restrictive, Schedule 3: needs a doctor's prescription, dispensed by a pharmacist. At the most restrictive, Schedule 4: prescription-only medicine. The listings below say which applies to which form, strength or pack size.
Schedule S3 to S4, as the Consolidated Schedules list it.
Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.
Consolidated Schedules listings for Physostigmine
S4: Physostigmine
- except ophthalmic preparations thereof when intended for glaucoma.
Consolidated Schedules 06 July 2026, line 7558
S3: Physostigmine
- ophthalmic preparations thereof, when intended for glaucoma.
Consolidated Schedules 06 July 2026, line 4124
This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.