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Pemetrexed

Schedule 4
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C20H21N5O6427.40 g/mol

(2S)-2-[[4-[2-(2-Amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid

Drag to rotate. Structure from PubChem CID 135410875.

Background

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Listing

Schedules
Schedule 4
Source
Consolidated Schedules 06 July 2026

Registered medicines

1 registered product listed

Counted through the register's ingredient index, which does not reach every record.

Registered products
NameBrandsDosagesApplicantsRegistrationsSchedule
PemetrexedAlimta, Lilly pemetrexed, Key pemetrexed, +14 more000 mg 1, 1 000, 100 mg, 100mg/ 500mg, +1 more12 applicants37 registrationsS4

2 more registered products name Pemetrexed in their active ingredient

Registered products
NameBrandsDosagesApplicantsRegistrationsSchedule
Pemetrexed disodium heptahydratePexitaz100 / 500 mgRanbaxy Pharmaceutical (Pty) Ltd2 registrationsS4
Pemetrexed diacidPemetrexed fresenius500 mgFresenius Kabi South Africa (Pty) Ltd560954S4

Regulatory status

Where S4 sits on the scale

Prescription-only medicine.

Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S4, as the Consolidated Schedules list it.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Pemetrexed

  • S4: Pemetrexed

    Consolidated Schedules 06 July 2026, line 7500

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

Research articles

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