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Drospirenone

Schedule 3 to 4, conditions apply
Loading the molecular structure
C24H30O3366.50 g/mol

(1R,2R,4R,10R,11S,14S,15S,16S,18S,19S)-10,14-Dimethylspiro[hexacyclo[9.8.0.02,4.05,10.014,19.016,18]nonadec-5-ene-15,5'-oxolane]-2',7-dione

Drag to rotate. Structure from PubChem CID 68873.

Background

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Listing

Schedules
Schedule 3 to 4, conditions apply
Source
Consolidated Schedules 06 July 2026

Registered medicines

2 registered products listed

Counted through the register's ingredient index, which does not reach every record.

Registered products
NameBrandsDosagesApplicantsRegistrationsSchedule
Drospirenone, estradiolAngeliq low doseNot statedBayer (Pty) Ltd û Isando509999S2 to S4conditions apply
DrospirenoneSlyndNot statedLebasi Pharmaceuticals (Pty) Ltd560367S3 to S4conditions apply

5 more registered products name Drospirenone in their active ingredient

Registered products
NameBrandsDosagesApplicantsRegistrationsSchedule
Drospirenone, ethinylestradiolYasmin, Yaz, Ruby, +18 more0,02 mg, 3,0 mg, 0,03 mg, 3,0 mg, 0,03 mg 3/0,, 3mg, +4 more9 applicants21 registrationsS4
Drospirenone, ethinylestradiol, levomefolateYaz plus, Yasmin plus, Ruby plus, +1 more3mg/0.02 mg/0.451 mg, 3mg/0.03 mg/0.451 mg2 applicants4 registrationsS4
Drospirenone, ethinyl estradiolOcaz, Leyla, Drosmyl, +2 moreNot stated4 applicants5 registrations
Drospirenone, estetrolDrovelisNot statedAdcock ingram limited560933
Drospirenone, each yellow contains levomefolate calcium, ethinylestradiol, levomefolateRubaz plus, RosnylevoNot statedPharma Dynamics (Pty) Ltd2 registrations

Regulatory status

Where S3 to S4 sits on the scale

Depends on which listing applies

At the least restrictive, Schedule 3: needs a doctor's prescription, dispensed by a pharmacist. At the most restrictive, Schedule 4: prescription-only medicine. The listings below say which applies to which form, strength or pack size.

Schedule S3 to S4, as the Consolidated Schedules list it.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Drospirenone

  • S4: Drospirenone

    • when intended for hormone replacement therapy;
    • except when intended for oral contraception. (S3)

    Consolidated Schedules 06 July 2026, lines 6127 to 6131

  • S3: Drospirenone

    • when intended for oral contraception;
    • except when intended for hormone replacement therapy. (S4)

    Consolidated Schedules 06 July 2026, lines 3490 to 3494

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

Research articles

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