Trimethoprim
5-[(3,4,5-Trimethoxyphenyl)methyl]pyrimidine-2,4-diamine
Drag to rotate. Structure from PubChem CID 5578.
Background
Listing
- Schedules
- Schedule 4, conditions apply
- Source
- Consolidated Schedules 06 July 2026
Registered medicines
4 registered products listed
Counted through the register's ingredient index, which does not reach every record.
| Name | Brands | Dosages | Applicants | Registrations | Schedule |
|---|---|---|---|---|---|
| Sulfamethoxazole, trimethoprim | Acuco, Thoxaprim, Xeroprim, +52 more | 80 mg,400 mg, tablets, suspension, 5 ml, +9 more | 26 applicants | 65 registrations | S4 |
| Isoniazid, pyridoxine, sulfamethoxazole, trimethoprim Cancelled | Isonoxale | Not stated | Cipla Medpro (Pty) Ltd | 520209.208 | S1 to S4conditions apply |
| Sulfadimidine, trimethoprim | Amphoprim | Not stated | Virbac Rsa (Pty) Ltd | 83/636 | S4 |
| Trimethoprim Cancelled | Purium | 100, 160, suspension, 200 | Pharmacare limited û woodmead | 4 registrations | S4 |
Regulatory status
Where S4 sits on the scale
Prescription-only medicine.
Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.
Schedule S4, as the Consolidated Schedules list it.
Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.
Consolidated Schedules listings for Trimethoprim
S4: Trimethoprim
- except when specifically intended and registered in combination with sulphonamides for the treatment of gastro-enteritis and pneumonia in terms of the provisions of the Fertilizers, Farm Feeds, Agricultural Remedies and Stock Remedies Act, 1947 (Act 36 of 1947).
Consolidated Schedules 06 July 2026, lines 8287 to 8289
This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.