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Adapalene

Schedule 3
Loading the molecular structure
C28H28O3412.50 g/mol

6-[3-(1-Adamantyl)-4-methoxyphenyl]naphthalene-2-carboxylic acid

Drag to rotate. Structure from PubChem CID 60164.

Background

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Listing

Schedules
Schedule 3
Source
Consolidated Schedules 06 July 2026

Registered medicines

1 registered product listed

Counted through the register's ingredient index, which does not reach every record.

Registered products
NameBrandsDosagesApplicantsRegistrationsSchedule
AdapaleneDifferin, Deriva, Dapta1 mg/g, 1mg, gel, cream3 applicants5 registrationsS3

1 more registered product name Adapalene in their active ingredient

Registered products
NameBrandsDosagesApplicantsRegistrationsSchedule
Adapalene, benzoyl peroxideEpiduo, Epiduo forte, Deriva co, +1 more0.1 % / 2.5 %, 0,1%/2,5%, 3 mg/g, 25 mg/g2 applicants4 registrations

Regulatory status

Where S3 sits on the scale

Needs a doctor's prescription, dispensed by a pharmacist.

Schedule 3 medicines can only be sold on a prescription from an authorised prescriber, such as a doctor or dentist. A pharmacist dispenses the medicine once they have the written prescription, or a verbal instruction from a prescriber they know. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S3, as the Consolidated Schedules list it.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Adapalene

  • S3: Adapalene

    Consolidated Schedules 06 July 2026, line 3120

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

Research articles

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