Orphenadrine
Sold as Orpadrex, Disipal, Norflex, Phenerine
N,N-Dimethyl-2-[(2-methylphenyl)-phenylmethoxy]ethanamine
Drag to rotate. Structure from PubChem CID 4601.
Background
Registration
- Applicants
- 4
- Registrations
- 4
- Schedule source
- SAHPRA documentation
Applicants and registrations
| Applicant | Brands | Dosages | Registrations | Schedule | Leaflets |
|---|---|---|---|---|---|
| The Premier Pharmaceutical Co LtdCancelled | Orpadrex | Not stated | C0675 | Not determined | None |
| Gulf Drug Company (Pty) Ltd | Disipal | Not stated | C0764 | Not determined | None |
| Inova Pharmaceuticals (Pty) Ltd | Norflex | Not stated | H1612 | Not determined | None |
| Pharmacare limited û woodmeadCertificate held by Pharmacare limited | Phenerine | 50 mg | L0234 | S4 | PI |
Variants
| Product | Strength and form | Registration | Status | Schedule | Leaflets |
|---|---|---|---|---|---|
| Orpadrex TABLET ORPHENADRINE HYDROCHLORIDE A 50 MG | Not listed | C0675 | Cancelled | Not determined | None |
| Disipal EACH TABLET CONTAINS ORPHENADRINE HYDROCHLORIDE A 50,0 mg | Not listed | C0764 | Old Medicine | Not determined | None |
| Norflex EACH TABLET CONTAINS ORPHENADRINE CITRATE A 100 mg | Not listed | H1612 | Old Medicine | Not determined | None |
| Phenerine EACH TABLET CONTAINS ORPHENADRINE HYDROCHLORIDE 50 mg | 50 mgSugar-coated tablet | L0234L/5.4.1/234Approved 8 December 1978 | Registered | S4 | PI |
Regulatory status
Where S4 sits on the scale
Prescription-only medicine.
Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.
Schedule S4, read from the product's PI-PIL leaflet.
Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.
Consolidated Schedules listings for Orphenadrine hydrochloride
S4: Orphenadrine
- except when contained in preparations intended for use as a muscle relaxant.
Consolidated Schedules 06 July 2026, line 7407
S2: Orphenadrine
- when contained in preparations intended for use as a muscle relaxant.
Consolidated Schedules 06 July 2026, line 2468
Pharmacological class: Anti-Parkinsonism preparations. (class 5.4.1)
This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.
SAHPRA documents
Schedule Verification
Phenerine, Pharmacare limited û woodmead is scheduled S4 in its official SAHPRA documents, read with 90% confidence.
These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.