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Lamivudine, tenofovir disoproxil

Sold as Tenolam, Tenlam, Mivuten, Medpro lamivudine & tenofovir, Tacidra, Gemuno, Nofdine, Telavir, Lamtenowin, Bitenlam, Lamtodin, Laberef, Tenalate, Relivzate

S4

Combination product

This product contains more than one active ingredient, so it has no single molecular structure.

Background

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Registration

Applicants
11
Registrations
14
Schedule source
Consolidated Schedules 06 July 2026

Applicants and registrations

ApplicantBrandsDosagesRegistrationsScheduleLeaflets
Pharmacare limited û woodmeadTenolamNot stated441050S4None
Trinity Pharma (Pty) LtdTenlamNot stated450105S4None
Cipla Medpro Manufacturing (Pty) LtdCertificate held by CiplaMivuten300mg450108S4PIPIL
Cipla Medpro (Pty) LtdCancelledMedpro lamivudine & tenofovir300/300450109S4None
Aurobindo Pharma (Pty) LtdCancelledTacidra300/300 mg451008S4None
Aurogen South Africa (Pty) LtdCancelledGemuno, Nofdine300/300 mg451058, 451059S4None
Ranbaxy (SA) (Pty) LtdCancelledTelavirNot stated470669S4None
Zentiva South Africa (Pty) LtdLamtenowinNot stated481303S4None
Specpharm (Pty) LtdCancelledBitenlamNot stated490704S4None
Macleods Pharmaceuticals SA (Pty) LtdCancelledLamtodin, Laberef, Tenalate300/300520067, 520068.067, 520069.068S4None
Austell Pharmaceuticals (Pty) LtdRelivzate300 mg, 245 mg570166S4PIPIL

Variants

ProductStrength and formRegistrationStatusScheduleLeaflets
Tenolam

EACH TABLET CONTAINS LAMIVUDINE 300,0 mg TENOFOVIR DISOPROXIL FUMARATE 300,0 mg

Not listed44105044/20.2.8/1050RegisteredS4None
Tenlam

EACH TABLET CONTAINS LAMIVUDINE 300,0 mg TENOFOVIR DISOPROXIL FUMARATE 300,0 mg

Not listed45010545/20.2.8/0105RegisteredS4None
Mivuten

EACH TABLET CONTAINS LAMIVUDINE 300,0 mg TENOFOVIR DISOPROXIL FUMARATE 300,0 mg

300mg. 300mgTablet45010845/20.2.8/0108Approved 8 April 2019RegisteredS4PIPIL
Medpro lamivudine & tenofovir 300/300

EACH TABLET CONTAINS LAMIVUDINE 300,0 mg TENOFOVIR DISOPROXIL FUMARATE 300,0 mg

300/30045010945/20.2.8/0109CancelledS4None
Tacidra 300/300 MG tablets

EACH TABLET CONTAINS LAMIVUDINE 300,0 mg TENOFOVIR DISOPROXIL FUMARATE 300,0 mg

300/300 mgTablets45100845/20.2.8/1008CancelledS4None
Gemuno tablets 300/300 MG

EACH TABLET CONTAINS LAMIVUDINE 300,0 mg TENOFOVIR DISOPROXIL FUMARATE 300,0 mg

300/300 mgTablets45105845/20.2.8/1058CancelledS4None
Nofdine 300/300 MG tablets

EACH TABLET CONTAINS LAMIVUDINE 300,0 mg TENOFOVIR DISOPROXIL FUMARATE 300,0 mg

300/300 mgTablets45105945/20.2.8/1059CancelledS4None
Telavir

EACH TABLET CONTAINS LAMIVUDINE 300,0 mg TENOFOVIR DISOPROXIL FUMARATE 300,0 mg

Not listed47066947/20.2.8/0669CancelledS4None
Lamtenowin

EACH TABLET CONTAINS LAMIVUDINE 300,0 mg TENOFOVIR DISOPROXIL FUMARATE 300,0 mg

Not listed48130348/20.2.8/1303RegisteredS4None
Bitenlam

EACH TABLET CONTAINS LAMIVUDINE 300,0 mg TENOFOVIR DISOPROXIL FUMARATE 300,0 mg

Not listed49070449/20.2.8/0704CancelledS4None
Lamtodin 300/300

EACH TABLET CONTAINS: TENOFOVIR DISOPROXIL FUMARATE 300,0 mg LAMIVUDINE 300,0 mg

300/30052006752/20.2.8/0067CancelledS4None
Laberef 300/300

EACH TABLET CONTAINS: TENOFOVIR DISOPROXIL FUMARATE 300,0 mg LAMIVUDINE 300,0 mg

300/300520068.06752/20.2.8/0068.067CancelledS4None
Tenalate 300/300

EACH TABLET CONTAINS: TENOFOVIR DISOPROXIL FUMARATE 300,0 mg LAMIVUDINE 300,0 mg

300/300520069.06852/20.2.8/0069.068CancelledS4None
Relivzate

LAMIVUDINE; TENOFOVIR DISOPROXIL FUMARATE

300 mg, 245 mgTablet57016657/20.2.8/0166Approved 21 November 2024RegisteredS4PIPIL

Regulatory status

Where S4 sits on the scale

Prescription-only medicine.

Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S4, matched to the Consolidated Schedules by ingredient, confidence medium.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Lamivudine, tenofovir disoproxil fumarate

  • S4: Lamivudine

    Consolidated Schedules 06 July 2026, line 6850

  • S4: Tenofovir

    Consolidated Schedules 06 July 2026, line 8130

Pharmacological class: Antiviral agents. (class 20.2.8)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

Mivuten, Cipla Medpro Manufacturing (Pty) Ltd is scheduled S4 in its official SAHPRA documents, read with 90% confidence.

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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