Hydrochlorothiazide, valsartan

Sold as Co-diovan, Co-tareg, Co-diovan plus, Co-tareg plus, Co zomevek, Co-migroben, Co migroben, Zomevek co, Regoval co, Diolo co plus, Diolo co, Valsartan ran co, Valstell plus, Diojub, Valgen co, Valheft co, Valazyd co, Valsartan hydrochlorothiazide zydus

S3Read from the PI-PIL document and verified

Combination product

This product contains more than one active ingredient, so it has no single molecular structure.

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Registration

Applicants: 10
Registrations: 37
Schedule source: SAHPRA documentation

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Novartis South Africa (Pty) LtdCertificate held by Novartis South Africa (Pty) Ltd.2 of 11 cancelled	Co-diovan, Co-tareg, Co-diovan plus, Co-tareg plus, Co-migroben, Co migroben	80/12.5, 160/12.5, 320/12.5, 320/25 mg, 80, 80/12,5, 160, 160/12,5, 160/25, 320/12,5, 320/25	320336, 340441, 350276, 370225, 410147, 410148, 410743, 410744, 430083, 430084, 430085	S3	PI PIL
Sandoz South Africa (Pty) Ltd2 of 5 cancelled	Co zomevek, Zomevek co	80/12,5, 160/12,5, 160/25, 320/12,5, 320/25	430080, 430081, 430082, 430463, 430464	S3	None
Pharma Dynamics (Pty) Ltd	Regoval co	80/12,5, 160/12,5, 160/25	440018, 440019, 440020	S3	PI PIL
Ranbaxy (SA) (Pty) LtdCancelled	Diolo co plus, Diolo co	160/25, 160/12,5	440477, 440479	S3	None
Ranbaxy Pharmaceutical (Pty) LtdCancelled	Diolo co	80/12,5	440478	S3	None
MSQ Pharma (Pty) Ltd	Valsartan ran co	80/12,5, 160/25, 160/12,5	440482, 440483, 440484	S3	None
Austell Pharmaceuticals (Pty) Ltd	Valstell plus	80/12,5, 160/12,5, 160/25	460243, 460244, 460245	S3	None
Jubilant Pharma SA (Pty) Ltd	Diojub, Valheft co	160/12,5, 160/25	471108, 471109, 480265, 480266	S3	None
Viatris Healthcare (Pty) Ltd	Valgen co	320 mg/12,5 mg	471253	S3	None
Zydus Healthcare (Pty) LtdCertificate held by Zydus Healthcare SA (Pty) Ltd	Valazyd co, Valsartan hydrochlorothiazide zydus	80/12,5, 160/12,5, 160/25	530566, 530569.566, 530570.567, 530571.568	S3	PI PIL

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Co-diovan EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 mg VALSARTAN 80,0 mg	80/12.5, 160/12.5, 320/12.5, 320/25 mgFilm-coated tablets.	32033632/7.1.3/0336Approved 12 March 2025	Registered	S3	PI PIL
Co-diovan 160 EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 mg VALSARTAN 160,0 mg	160	34044134/7.1.3/0441	Registered	S3	None
Co-tareg 80 EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 mg VALSARTAN 80,0 mg	80	35027635/7.1.3/0276	Registered	S3	None
Co-diovan 160 plus EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 25,0 mg VALSARTAN 160,0 mg	160	37022537/7.1.3/0225	Cancelled	S3	None
Co-diovan 320/12,5 tablets EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 mg VALSARTAN 320,0 mg	320/12,5Tablets	41014741/7.1.3/0147	Registered	S3	None
Co-diovan 320/25 tablets EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 25,0 mg VALSARTAN 320,0 mg	320/25Tablets	41014841/7.1.3/0148	Registered	S3	None
Co-tareg 160 EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 mg VALSARTAN 160,0 mg	160	41074341/7.1.3/0743	Registered	S3	None
Co-tareg 160 plus EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 25,0 mg VALSARTAN 160,0 mg	160	41074441/7.1.3/0744	Registered	S3	None
Co zomevek 80/12,5 EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 mg VALSARTAN 80,0 mg	80/12,5	43008043/7.1.3/0080	Registered	S3	None
Co zomevek 160/12,5 EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 mg VALSARTAN 160,0 mg	160/12,5	43008143/7.1.3/0081	Registered	S3	None
Co zomevek 160/25 EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 25,0 mg VALSARTAN 160,0 mg	160/25	43008243/7.1.3/0082	Registered	S3	None
Co-migroben 80/12,5 tablet EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 mg VALSARTAN 80,0 mg	80/12,5Tablet	43008343/7.1.3/0083	Registered	S3	None
Co migroben 160/12,5 EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 mg VALSARTAN 160,0 mg	160/12,5Film-coated tablets.	43008443/7.1.3/0084Approved 12 March 2025	Registered	S3	PI PIL
Co migroben 160/25 EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 25,0 mg VALSARTAN 160,0 mg	160/25Film-coated tablets.	43008543/7.1.3/0085Approved 12 March 2025	Cancelled	S3	PI PIL
Zomevek co 320/12,5 tablet EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 mgVALSARTAN 320,0 mg	320/12,5Tablet	43046343/7.1.3/0463	Cancelled	S3	None
Zomevek co 320/25 tablet EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 25,0 mgVALSARTAN 320,0 mg	320/25Tablet	43046443/7.1.3/0464	Cancelled	S3	None
Regoval co 80/12,5 EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 mg VALSARTAN 80,0 mg	80/12,5Film-coated tablets.	44001844/7.1.3/0018Approved 11 October 2023	Registered	S3	PI PIL
Regoval co 160/12,5 EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 mg VALSARTAN 160,0 mg	160/12,5Film-coated tablets.	44001944/7.1.3/0019Approved 11 October 2023	Registered	S3	PI PIL
Regoval co 160/25 EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 25,0 mg VALSARTAN 160,0 mg	160/25Film-coated tablets.	44002044/7.1.3/0020Approved 11 October 2023	Registered	S3	PI PIL
Diolo co plus 160/25 EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 25,0 mg VALSARTAN 160 ,0 mg	160/25	44047744/7.1.3/0477	Cancelled	S3	None
Diolo co 80/12,5 EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 mgVALSARTAN 80 ,0 mg	80/12,5	44047844/7.1.3/0478	Cancelled	S3	None
Diolo co 160/12,5 EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 mg VALSARTAN 160 ,0 mg	160/12,5	44047944/7.1.3/0479	Cancelled	S3	None
Valsartan ran co 160/25 EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 25,0 mg VALSARTAN 160 ,0 mg	160/25	44048244/7.1.3/0482	Registered	S3	None
Valsartan ran co 80/12,5 EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 mg VALSARTAN 80 ,0 mg	80/12,5	44048344/7.1.3/0483	Registered	S3	None
Valsartan ran co 160/12,5 EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 mg VALSARTAN 160 ,0 mg	160/12,5	44048444/7.1.3/0484	Registered	S3	None
Valstell plus 80/12,5 EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 mg VALSARTAN 80,0 mg	80/12,5	46024346/7.1.3/0243	Registered	S3	None
Valstell plus 160/12,5 EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 mg VALSARTAN 160,0 mg	160/12,5	46024446/7.1.3/0244	Registered	S3	None
Valstell plus 160/25 EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 25,0 mg VALSARTAN 160,0 mg	160/25	46024546/7.1.3/0245	Registered	S3	None
Diojub 160/12,5 Each tablet contains VALSARTAN 160,0 mg and HYDROCHLOROTHIAZIDE 12,5 mg	160/12,5	47110847/7.1.3/1108	Registered	S3	None
Diojub 160/25 Each tablet contains VALSARTAN 160,0 mg and HYDROCHLOROTHIAZIDE 25,0 mg	160/25	47110947/7.1.3/1109	Registered	S3	None
Valgen co 320 mg/12,5 MG EACH TABLET CONTAINS VALSARTAN 320,0 mg and HYDROCHLOROTHIAZIDE 12,5 mg	320 mg/12,5 mg	47125347/7.1.3/1253	Registered	S3	None
Valheft co 160/12,5 Each tablet contains VALSARTAN 160,0 mg and HYDROCHLOROTHIAZIDE 12,5 mg	160/12,5	48026548/7.1.3/0265	Registered	S3	None
Valheft co 160/25 Each tablet contains VALSARTAN 160,0 mg and HYDROCHLOROTHIAZIDE 25,0 mg	160/25	48026648/7.1.3/0266	Registered	S3	None
Valazyd co 80/12,5 EACH TABLET CONTAINS VALSARTAN 80,0 mg HYDROCHLOROTHIAZIDE 12,5 mg	80/12,5Film-coated tablet	53056653/7.1.3/0566Approved 3 September 2024	Registered	S3	PI PIL
Valsartan hydrochlorothiazide 80/12,5 zydus EACH TABLET CONTAINS VALSARTAN 80,0 mg HYDROCHLOROTHIAZIDE 12,5 mg	80/12,5Fim-coated tablets	530569.56653/7.1.3/0569.566Approved 3 September 2024	Registered	S3	PI PIL
Valsartan hydrochlorothiazide 160/12,5 zydus EACH TABLET CONTAINS VALSARTAN 160,0 mg HYDROCHLOROTHIAZIDE 12,5 mg	160/12,5Fim-coated tablets	530570.56753/7.1.3/0570.567Approved 3 September 2024	Registered	S3	PI PIL
Valsartan hydrochlorothiazide 160/25 zydus EACH TABLET CONTAINS VALSARTAN 160,0 mg HYDROCHLOROTHIAZIDE 25,0 mg	160/25Fim-coated tablets	530571.56853/7.1.3/0571.568Approved 3 September 2024	Registered	S3	PI PIL

Regulatory status

Where S3 sits on the scale

S0S1S2S3S4S5S6S7S8

Needs a doctor's prescription, dispensed by a pharmacist.

Schedule 3 medicines can only be sold on a prescription from an authorised prescriber, such as a doctor or dentist. A pharmacist dispenses the medicine once they have the written prescription, or a verbal instruction from a prescriber they know. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S3, read from the product's PI-PIL leaflet.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Hydrochlorothiazide, valsartan

S3: Hydrochlorothiazide
Consolidated Schedules 06 July 2026, line 3721
S3: Valsartan
Consolidated Schedules 06 July 2026, line 4376

Pharmacological class: Other hypotensives. (class 7.1.3)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

Co-diovan, Novartis South Africa (Pty) Ltd is scheduled S3 in its official SAHPRA documents, read with 90% confidence.

Professional information (PI)For healthcare professionalsCo-diovan, Novartis South Africa (Pty) Ltd Patient information leaflet (PIL)For patients and carersCo-diovan, Novartis South Africa (Pty) Ltd

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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