Hydrochlorothiazide, quinapril
Sold as Accuretic, Accumax co, Quinapril hydrochlorothiazide zydus, Kwinco, Quinapril plus htz oethmaan
(3S)-2-[(2S)-2-[[(2S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid
Drag to rotate. Structure from PubChem CID 54892.
Background
Registration
- Applicants
- 4
- Registrations
- 10
- Schedule source
- Consolidated Schedules 06 July 2026
Applicants and registrations
| Applicant | Brands | Dosages | Registrations | Schedule | Leaflets |
|---|---|---|---|---|---|
| Pfizer Laboratories (Pty) LtdCancelled | Accuretic, Accumax co | 10/12,5, 20/12,5 | 270165, 270166, 340233, 340234 | S3 | None |
| Zydus Healthcare (Pty) Ltd | Quinapril hydrochlorothiazide zydus | 10/12,5, 20/12,5 | 430473, 430474 | Not determined | None |
| Aurogen South Africa (Pty) Ltd | Kwinco | 10/12,5 mg, 20/12,5 mg | 431046, 431047 | Not determined | None |
| Oethmaan Biosims (Pty) Ltd | Quinapril plus htz oethmaan | 10/12,5, 20/12,5 | A380392, A380393 | Not determined | None |
Variants
| Product | Strength and form | Registration | Status | Schedule | Leaflets |
|---|---|---|---|---|---|
| Accuretic 10/12,5 EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 mg QUINAPRIL HYDROCHLORIDE EQUIVALENT TO 10 mg QUINAPRIL | 10/12,5 | 27016527/7.1.3/0165 | Cancelled | Not determined | None |
| Accuretic 20/12,5 EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 MG QUINAPRIL HYDROCHLORIDE 21,7 MG EQUIVALENT TO 20 MG QUINAPRIL | 20/12,5 | 27016627/7.1.3/0166 | Cancelled | S3 | None |
| Accumax co 10/12,5 EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 mg QUINAPRIL HYDROCHLORIDE EQUIVALENT TO QUINAPRIL 10,0 mg | 10/12,5 | 34023334/7.1.3/0233 | Cancelled | Not determined | None |
| Accumax co 20/12,5 EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 mg QUINAPRIL HYDROCHLORIDE EQUIVALENT TO QUINAPRIL 20,0 mg | 20/12,5 | 34023434/7.1.3/0234 | Cancelled | Not determined | None |
| Quinapril hydrochlorothiazide zydus 10/12,5 EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 mg QUINAPRIL HYDROCHLORIDE EQUIVALENT TO QUINAPRIL 10,0 mg | 10/12,5 | 43047343/7.1.3/0473 | Registered | Not determined | None |
| Quinapril hydrochlorothiazide zydus 20/12,5 EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 mg QUINAPRIL HYDROCHLORIDE EQUIVALENT TO QUINAPRIL 20,0 mg | 20/12,5 | 43047443/7.1.3/0474 | Registered | Not determined | None |
| Kwinco 10/12,5 MG EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 mg QUINAPRIL HYDROCHLORIDE EQUIVALENT TO QUINAPRIL 10,0 mg | 10/12,5 mg | 43104643/7.1.3/1046 | Registered | Not determined | None |
| Kwinco 20/12,5 MG EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 mg QUINAPRIL HYDROCHLORIDE EQUIVALENT TO QUINAPRIL 20,0 mg | 20/12,5 mg | 43104743/7.1.3/1047 | Registered | Not determined | None |
| Quinapril plus htz 10/12,5 oethmaan EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 mg QUINAPRIL HYDROCHLORIDE EQUIVALENT TO QUINAPRIL 10,0 mg | 10/12,5 | A380392A38/7.1.3/0392 | Registered | Not determined | None |
| Quinapril plus htz 20/12,5 oethmaan EACH TABLET CONTAINS HYDROCHLOROTHIAZIDE 12,5 mg QUINAPRIL HYDROCHLORIDE EQUIVALENT TO QUINAPRIL 20,0 mg | 20/12,5 | A380393A38/7.1.3/0393 | Registered | Not determined | None |
Regulatory status
Where S3 sits on the scale
Needs a doctor's prescription, dispensed by a pharmacist.
Schedule 3 medicines can only be sold on a prescription from an authorised prescriber, such as a doctor or dentist. A pharmacist dispenses the medicine once they have the written prescription, or a verbal instruction from a prescriber they know. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.
Schedule S3, matched to the Consolidated Schedules by ingredient, confidence medium.
Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.
Consolidated Schedules listings for Hydrochlorothiazide, quinapril hydrochloride
S3: Hydrochlorothiazide
Consolidated Schedules 06 July 2026, line 3721
S3: Quinapril
Consolidated Schedules 06 July 2026, line 4197
Pharmacological class: Other hypotensives. (class 7.1.3)
This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.
SAHPRA documents
SAHPRA has not published a professional information or patient information leaflet for this product.