Zidovudine

Sold as Retrovir iv, Apo-zidovudine, Garec-zidovudine, Cipla-zidovudine, Aspen zidovudine, Bio zidovudine, Adco-zidovudine, Vari-zidovudine, Zydorin, Adco-zidovudine alcohol and sugar free, Dozra, Zynovir, Pharma-q zidovudine, Hevuzid, Dizovin, Zidomat, Zidovudine SPEC, Zidovudine winthrop, Zidovudine sandoz, Zidersip, Zidoleod, Sonke-zidovudine

S4Read from the PI-PIL document and verified

C₁₀H₁₃N₅O₄267.24 g/mol

1-[(2R,4S,5S)-4-Azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

Drag to rotate. Structure from PubChem CID 35370.

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Registration

Applicants: 19
Registrations: 36
Schedule source: SAHPRA documentation

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Glaxosmithkline South Africa (Pty) LimitedCertificate held by Glaxosmithkline South Africa (Pty) Ltd	Retrovir iv	200 mg/20 mL	290483	S4	PI PIL
Apotex SA (Pty) LtdCancelled	Apo-zidovudine	100 mg	320529	S4	None
Garec (Pty) LtdCancelled	Garec-zidovudine	100 mg	320646	S4	None
Cipla Medpro (Pty) LtdCertificate held by CiplaCancelled	Cipla-zidovudine	100mg, 300	340142, 380215	S4	PI PIL
Pharmacare limited û woodmead	Aspen zidovudine	300 mg, syrup, 100 mg, 250 mg	380230, A380635, A390249, A390250	S4	None
Biotech Laboratories (Pty) Ltd	Bio zidovudine, Zydorin	300, syrup	410231, 410509	S4	None
Adcock ingram limited	Adco-zidovudine, Adco-zidovudine alcohol and sugar free	tablets, syrup, 50 mg/5 ml, 100 mg, 250 mg	410237, 410510, 410511, 410737, 410738	S4	PI PIL
Lebasi Pharmaceuticals (Pty) LtdCancelled	Vari-zidovudine	300 mg	410296	S4	None
Novagen Pharma (Pty) LtdCancelled	Dozra	50 mg/5 ml, 100 mg, 250 mg, 300 mg	410680, 410681, A400383, A400562	S4	None
Aurobindo Pharma (Pty) Ltd2 of 3 cancelled	Zynovir	50 mg/5 ml, 100 mg, 250 mg	410685, 410686, 420987	S4	None
Pharma-q Holdings (Pty) Ltd	Pharma-q zidovudine	50 mg	420047	S4	None
Bliss Pharmaceuticals (Pty) LtdCancelled	Hevuzid	Not stated	440593	S4	None
Macleods Pharmaceuticals SA (Pty) Ltd	Dizovin, Zidoleod	50 mg/5 ml, 100, 300	450085, 450086, 610876	S4	None
Viatris Healthcare (Pty) Ltd	Zidomat	100 mg, 300 mg	460008, 460009	S4	None
Specpharm (Pty) LtdCancelled	Zidovudine SPEC	50 mg/5 ml	460170	S4	None
Winthrop Pharmaceuticals (Pty) Ltd	Zidovudine winthrop	Not stated	470861	S4	None
Sandoz South Africa (Pty) Ltd	Zidovudine sandoz	300 mg	490503	S4	None
Hetero Drugs South Africa (Pty) Ltd	Zidersip	oral solution	491048	S4	None
Ranbaxy Pharmaceutical (Pty) LtdCancelled	Sonke-zidovudine	300	A400303	S4	None

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Retrovir iv EACH 20 ml VIAL CONTAINS ZIDOVUDINE 200 mg	200 mg/20 mLInfusion	29048329/20.2.8/0483Approved 1 November 2023	Registered	S4	PI PIL
Apo-zidovudine 100 MG EACH CAPSULE CONTAINS ZIDOVUDINE 100,0 mg	100 mg	32052932/20.2.8/0529	Cancelled	S4	None
Garec-zidovudine 100 MG EACH CAPSULE CONTAINS ZIDOVUDINE 100,0 mg	100 mg	32064632/20.2.8/0646	Cancelled	S4	None
Cipla-zidovudine EACH CAPSULE CONTAINS ZIDOVUDINE 100,0 mg	100mgCapsule	34014234/20.2.8/0142Approved 31 January 2014	Cancelled	S4	PI PIL
Cipla-zidovudine 300 EACH TABLET CONTAINS ZIDOVUDINE 300,0 mg	300	38021538/20.2.8/0215	Cancelled	S4	None
Aspen zidovudine 300 MG EACH TABLET CONTAINS ZIDOVUDINE 300,0 mg	300 mg	38023038/20.2.8/0230	Registered	S4	None
Bio zidovudine 300 EACH TABLET CONTAINS ZIDOVUDINE 300,0 mg	300	41023141/20.2.8/0231	Registered	S4	None
Adco-zidovudine tablets EACH TABLET CONTAINS: ZIDOVUDINE 300,0 mg	Tablets	41023741/20.2.8/0237	Registered	S4	None
Vari-zidovudine 300 MG EACH TABLET CONTAINS ZIDOVUDINE 300,0 mg	300 mg	41029641/20.2.8/0296	Cancelled	S4	None
Zydorin syrup EACH 5,0 ml SYRUP CONTAINS ZIDOVUDINE 50,0 mg	Syrup	41050941/20.2.8/0509	Registered	S4	None
Adco-zidovudine syrup alcohol and sugar free EACH 5,0 ml SYRUP CONTAINS ZIDOVUDINE 50,0 mg	Syrup	41051041/20.2.8/0510	Registered	S4	None
Adco-zidovudine syrup EACH 5,0 ml SYRUP CONTAINS :ZIDOVUDINE 50,0 mg	50 mg/5 mlSyrup.	41051141/20.2.8/0511Approved 31 July 2023	Registered	S4	PI PIL
Dozra 100 MG EACH CAPSULE CONTAINS ZIDOVUDINE 100,0 mg	100 mg	41068041/20.2.8/0680	Cancelled	S4	None
Dozra 250 MG EACH CAPSULE CONTAINS ZIDOVUDINE 250,0 mg	250 mg	41068141/20.2.8/0681	Cancelled	S4	None
Zynovir capsules 100 MG EACH CAPSULE CONTAINS ZIDOVUDINE 100,0 mg	100 mgCapsules	41068541/20.2.8/0685	Cancelled	S4	None
Zynovir capsules 250 MG EACH CAPSULE CONTAINS ZIDOVUDINE 250,0 mg	250 mgCapsules	41068641/20.2.8/0686	Cancelled	S4	None
Adco-zidovudine 100 MG capsules EACH CAPSULE CONTAINS ZIDOVUDINE 100,0 mg	100 mgCapsules	41073741/20.2.8/0737	Registered	S4	None
Adco-zidovudine 250 MG capsules EACH CAPSULE CONTAINS ZIDOVUDINE 250,0 mg	250 mgCapsules	41073841/20.2.8/0738	Registered	S4	None
Pharma-q zidovudine syrup 50 MG EACH 5,0 ml SYRUP CONTAINS ZIDOVUDINE 50,0 mg	50 mgSyrup	42004742/20.2.8/0047	Registered	S4	None
Zynovir oral solution 50 mg/5 ML EACH 5,0 ml SOLUTION CONTAINS ZIDOVUDINE 50,0 mg	50 mg/5 mlOral solution	42098742/20.2.8/0987	Registered	S4	None
Hevuzid EACH TABLET CONTAINS ZIDOVUDINE 300,0 mg	Not listed	44059344/20.2.8/0593	Cancelled	S4	None
Dizovin 100 EACH CAPSULE CONTAINS:ZIDOVUDINE 100,0 mg	100	45008545/20.2.8/0085	Registered	S4	None
Dizovin 300 EACH TABLET CONTAINS:ZIDOVUDINE 300,0 mg	300	45008645/20.2.8/0086	Registered	S4	None
Zidomat 100 MG EACH TABLET CONTAINS ZIDOVUDINE 100,0 mg	100 mg	46000846/20.2.8/0008	Registered	S4	None
Zidomat 300 MG EACH TABLET CONTAINS ZIDOVUDINE 300,0 mg	300 mg	46000946/20.2.8/0009	Registered	S4	None
Zidovudine SPEC oral 50 mg/5 ML EACH 5,0 ml SOLUTION CONTAINS ZIDOVUDINE 50,0 mg	50 mg/5 mlOral	46017046/20.2.8/0170	Cancelled	S4	None
Zidovudine winthrop EACH TABLET CONTAINS ZIDOVUDINE 300,0 mg	Not listed	47086147/20.2.8/0861	Registered	S4	None
Zidovudine sandoz 300 MG EACH TABLET CONTAINS : ZIDOVUDINE 300,0 mg	300 mg	49050349/20.2.8/0503	Registered	S4	None
Zidersip oral solution EACH 5,0 ml SOLUTION CONTAINS : ZIDOVUDINE 50,0 mg	Oral solution	49104849/20.2.8/1048	Registered	S4	None
Zidoleod 50 mg/5 ML EACH 5,0 ml SOLUTION CONTAINS: ZIDOVUDINE 50,0 mg	50 mg/5 ml	61087661/20.2.8/0876	Registered	S4	None
Aspen zidovudine syrup EACH 5,0 ml SYRUP CONTAINS ZIDOVUDINE 50,0 mg	Syrup	A380635A38/20.2.8/0635	Registered	S4	None
Aspen zidovudine 100 MG EACH CAPSULE CONTAINS ZIDOVUDINE 100,0 mg	100 mg	A390249A39/20.2.8/0249	Registered	S4	None
Aspen zidovudine 250 MG EACH CAPSULE CONTAINS ZIDOVUDINE 250,0 mg	250 mg	A390250A39/20.2.8/0250	Registered	S4	None
Sonke-zidovudine 300 EACH TABLET CONTAINS ZIDOVUDINE 300,0 mg	300	A400303A40/20.2.8/0303	Cancelled	S4	None
Dozra 300 MG tablets EACH TABLET CONTAINS ZIDOVUDINE 300,0 mg	300 mgTablets	A400383A40/20.2.8/0383	Cancelled	S4	None
Dozra 50 mg/5 ML oral solution EACH 5,0 ml SOLUTION CONTAINS ZIDOVUDINE 50,0 mg	50 mg/5 mlOral solution	A400562A40/20.2.8/0562	Cancelled	S4	None

Regulatory status

Where S4 sits on the scale

S0S1S2S3S4S5S6S7S8

Prescription-only medicine.

Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S4, read from the product's PI-PIL leaflet.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Zidovudine

S4: Zidovudine
Consolidated Schedules 06 July 2026, line 8412

Pharmacological class: Antiviral agents. (class 20.2.8)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

Retrovir iv, Glaxosmithkline South Africa (Pty) Limited is scheduled S4 in its official SAHPRA documents, read with 90% confidence.

Professional information (PI)For healthcare professionalsRetrovir iv, Glaxosmithkline South Africa (Pty) Limited Patient information leaflet (PIL)For patients and carersRetrovir iv, Glaxosmithkline South Africa (Pty) Limited

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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