Valproic acid
Sold as Embivil mr, Lepquity, Convulex
Background
Registration
- Applicants
- 3
- Registrations
- 6
- Schedule source
- Consolidated Schedules 06 July 2026
Applicants and registrations
| Applicant | Brands | Dosages | Registrations | Schedule | Leaflets |
|---|---|---|---|---|---|
| Austell Pharmaceuticals (Pty) Ltd | Embivil mr | 250 mg, 500 mg | 550504, 550505 | S3 | None |
| Equity Pharmaceutical (Pty) Ltd | Lepquity | Not stated | 570189 | S3 | None |
| Acino Pharma (Pty) Ltd | Convulex | 150, 300, 500 | R0218, R0219, W0020 | S3 | None |
Variants
| Product | Strength and form | Registration | Status | Schedule | Leaflets |
|---|---|---|---|---|---|
| Embivil mr 250 MG EACH TABLET CONTAINS VALPROATE SEMISODIUM EQUIVALENT TO VALPROIC ACID 250,0 mg | 250 mg | 55050455/2.5/0504 | Registered | S3 | None |
| Embivil mr 500 MG EACH TABLET CONTAINS VALPROATE SEMISODIUM EQUIVALENT TO VALPROIC ACID 500,0 mg | 500 mg | 55050555/2.5/0505 | Registered | S3 | None |
| Lepquity Each 5,0 ml Solution contains: Valproic Acis 250,0 mg | Not listed | 57018957/2.5/0189 | Registered | S3 | None |
| Convulex 150 EACH CAPSULE CONTAINS VALPROIC ACID 150,0 mg | 150 | R0218R/2.5/218 | Registered | S3 | None |
| Convulex 300 EACH CAPSULE CONTAINS VALPROIC ACID 300,0 mg | 300 | R0219R/2.5/219 | Registered | S3 | None |
| Convulex 500 EACH CAPSULE CONTAINS VALPROIC ACID 500,0 mg | 500 | W0020W/2.5/20 | Registered | S3 | None |
Regulatory status
Where S3 sits on the scale
Needs a doctor's prescription, dispensed by a pharmacist.
Schedule 3 medicines can only be sold on a prescription from an authorised prescriber, such as a doctor or dentist. A pharmacist dispenses the medicine once they have the written prescription, or a verbal instruction from a prescriber they know. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.
Schedule S3, matched to the Consolidated Schedules by ingredient, confidence high.
Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.
Consolidated Schedules listings for Valproate semisodium equivalent to valproic acid
S3: Valproic acid
- unless listed in another Schedule.
Consolidated Schedules 06 July 2026, line 4374
Pharmacological class: Anticonvulsants, including anti-epileptics. (class 2.5)
This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.
SAHPRA documents
SAHPRA has not published a professional information or patient information leaflet for this product.