Trazodone
Sold as Aspen trazodone, Bio-trazodone, Zadopax, Trazodone accord, Dazatrone, Molipaxin
2-[3-[4-(3-Chlorophenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Drag to rotate. Structure from PubChem CID 5533.
Background
Registration
- Applicants
- 5
- Registrations
- 12
- Schedule source
- Consolidated Schedules 06 July 2026
Applicants and registrations
| Applicant | Brands | Dosages | Registrations | Schedule | Leaflets |
|---|---|---|---|---|---|
| Pharmacare limited û woodmead | Aspen trazodone | 50 mg, 100 mg | 370491, 370492 | S5 | None |
| Biotech Laboratories (Pty) Ltd | Bio-trazodone, Dazatrone | 50, 100 | 430698, 430699, 590657, 590658 | S5 | None |
| Austell Pharmaceuticals (Pty) Ltd | Zadopax | 50, 100 | 540520, 540521 | S5 | None |
| Accord Healthcare (Pty) Ltd | Trazodone accord | 50, 100 | 570667, 570668 | S5 | None |
| Sanofi-aventis South Africa (Pty) LtdCancelled | Molipaxin | 50 mg, 100 mg | E0009, E0010 | S5 | None |
Variants
| Product | Strength and form | Registration | Status | Schedule | Leaflets |
|---|---|---|---|---|---|
| Aspen trazodone 50 MG EACH CAPSULE CONTAINS TRAZODONE 50,0 mg | 50 mg | 37049137/1.2/0491 | Registered | S5 | None |
| Aspen trazodone 100 MG EACH CAPSULE CONTAINS TRAZODONE HYDROCHLORIDE 100,0 mg | 100 mg | 37049237/1.2/0492 | Registered | S5 | None |
| Bio-trazodone 50 EACH CAPSULE CONTAINS TRAZODONE HYDROCHLORIDE 50,0 mg | 50 | 43069843/1.2/0698 | Registered | S5 | None |
| Bio-trazodone 100 EACH CAPSULE CONTAINS TRAZODONE HYDROCHLORIDE 100,0 mg | 100 | 43069943/1.2/0699 | Registered | S5 | None |
| Zadopax 50 EACH CAPSULE CONTAINS TRAZODONE HYDROCHLORIDE 50,0 mg | 50 | 54052054/1.2/0520 | Registrered | S5 | None |
| Zadopax 100 EACH CAPSULE CONTAINS TRAZODONE HYDROCHLORIDE 100,0 mg | 100 | 54052154/1.2/0521 | Registrered | S5 | None |
| Trazodone 50 accord EACH TABLET CONTAINS: TRAZODONE HYDROCHLORIDE 50,0 mg | 50 | 57066757/1.2/0667 | Registered | S5 | None |
| Trazodone 100 accord EACH TABLET CONTAINS: TRAZODONE HYDROCHLORIDE 100,0 mg | 100 | 57066857/1.2/0668 | Registered | S5 | None |
| Dazatrone 50 EACH CAPSULE CONTAINS TRAZODONE HYDROCHLORIDE 50,0 mg | 50 | 59065759/1.2/0657 | Registered | S5 | None |
| Dazatrone 100 EACH CAPSULE CONTAINS TRAZODONE HYDROCHLORIDE 100,0 mg | 100 | 59065859/1.2/0658 | Registered | S5 | None |
| Molipaxin 50 MG capsule EACH CAPSULE CONTAINS TRAZODONE HYDROCHLORIDE 50 mg | 50 mgCapsule | E0009E/1.2/9 | Cancelled | S5 | None |
| Molipaxin 100 MG capsule EACH CAPSULE CONTAINS TRAZODONE HYDROCHLORIDE 100 mg | 100 mgCapsule | E0010E/1.2/10 | Cancelled | S5 | None |
Regulatory status
Where S5 sits on the scale
Prescription-only, with tighter controls on repeats.
Schedule 5 medicines need a prescription, and repeat dispensing is capped at six months in total; the prescriber must state upfront how many times, and at what intervals, it may be repeated. Extra limits apply to some uses: if it is being used for its anxiolytic, antidepressant, tranquillising or analgesic properties, it cannot be prescribed for longer than six months without a further consultation. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.
Schedule S5, matched to the Consolidated Schedules by ingredient, confidence high.
Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it.
Consolidated Schedules listings for Trazodone
S5: Trazodone
Consolidated Schedules 06 July 2026, line 9729
Pharmacological class: Psychoanaleptics (antidepressants). (class 1.2)
This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.
SAHPRA documents
SAHPRA has not published a professional information or patient information leaflet for this product.