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Topiramate (Topamax, Topamax Sc, Topalex)

Topiramate

Janssen Pharmaceutica (Pty) Ltd

S3

Registration

Applicant
Janssen Pharmaceutica (Pty) Ltd
Registrations
10
Schedule source
Consolidated Schedules 06 July 2026

Variants

ProductStrength and formRegistrationStatusScheduleLeaflets
Topamax 25 MG

EACH TABLET CONTAINS TOPIRAMATE 25 mg

25 mg30023630/2.5/0236RegisteredS3None
Topamax 50 MG

EACH TABLET CONTAINS TOPIRAMATE 50 mg

50 mg30023730/2.5/0237RegisteredS3None
Topamax 100 MG

EACH TABLET CONTAINS TOPIRAMATE 100 mg

100 mg30023830/2.5/0238RegisteredS3None
Topamax 200 MG

EACH TABLET CONTAINS TOPIRAMATE 200 mg

200 mg30023930/2.5/0239RegisteredS3None
Topamax sc 15 MG

EACH CAPSULE CONTAINS TOPIRAMATE 15,0 mg

15 mg32066232/2.5/0662RegisteredS3None
Topamax sc 25 MG

EACH CAPSULE CONTAINS TOPIRAMATE 25,0 mg

25 mg32066332/2.5/0663RegisteredS3None
Topamax sc 50 MG

EACH CAPSULE CONTAINS TOPIRAMATE 50,0 mg

50 mg32066432/2.5/0664RegisteredS3None
Topalex 25 MG

EACH TABLET CONTAINS TOPIRAMATE 25,0 mg

25 mg41062241/2.5/0622RegisteredS3None
Topalex 50 MG

EACH TABLET CONTAINS TOPIRAMATE 50,0 mg

50 mg41062341/2.5/0623RegisteredS3None
Topalex 100 MG

EACH TABLET CONTAINS TOPIRAMATE 100,0 mg

100 mg41062441/2.5/0624RegisteredS3None

Regulatory status

Where S3 sits on the scale

Needs a doctor's prescription, dispensed by a pharmacist.

Schedule 3 medicines can only be sold on a prescription from an authorised prescriber, such as a doctor or dentist. A pharmacist dispenses the medicine once they have the written prescription, or a verbal instruction from a prescriber they know. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S3, matched to the Consolidated Schedules by ingredient, confidence high.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Topiramate

  • S3: Topiramate

    Consolidated Schedules 06 July 2026, line 4341

Pharmacological class: Anticonvulsants, including anti-epileptics. (class 2.5)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

C12H21NO8S339.36 g/mol

[(1R,2S,6S,9R)-4,4,11,11-Tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecan-6-yl]methyl sulfamate

Drag to rotate. Structure from PubChem CID 5284627.

SAHPRA documents

SAHPRA has not published a professional information or patient information leaflet for this product.

Background

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Research articles

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