Tigecycline

Sold as Tigecycline pfizer, Tacyl, Cytagil iv, Gaticil iv iv, Rubicil, Tigebax, Tigecycline adco, Tizeg, Tigejex, Tygiv, Tyclin, Tygacil

S4Read from the PI-PIL document and verified

C₂₉H₃₉N₅O₈585.60 g/mol

(4S,4AS,5aR,12aR)-9-[[2-(tert-butylamino)acetyl]amino]-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide

Drag to rotate. Structure from PubChem CID 54686904.

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Registration

Applicants: 9
Registrations: 12
Schedule source: SAHPRA documentation

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Pfizer Laboratories (Pty) LtdCertificate held by Pfizer	Tigecycline pfizer, Tygacil	50 mg, 50mg / 5ml	530075, A400230	S4	PI PIL
Teva Pharmaceuticals (Pty) LtdCancelled	Tacyl	50,0 mg	530630	S4	PI PIL
Pharma Dynamics (Pty) Ltd1 of 2 cancelled	Cytagil iv, Gaticil iv iv	50 mg	530715, 530716.715	S4	PI PIL
Ruby Pharmaceuticals (Pty) Ltd	Rubicil	Not stated	530730	S4	None
Glenmark Pharmaceuticals South Africa (Pty) Ltd	Tigebax	Not stated	540165	S4	None
Adcock ingram limited	Tigecycline adco	50 mg	550750	S4	PI PIL
Ranbaxy Pharmaceuticals (Pty) Ltd	Tizeg	50 mg	560531	S4	PI PIL
Lamar International (Pty) Ltd	Tigejex	50 mg	580015	S4	PI PIL
Abex Pharmaceutica (Pty) Ltd	Tygiv, Tyclin	50 mg	590423, 590424.423	S4	PI PIL

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Tigecycline 50 MG pfizer TIGECYCLINE	50 mgSterile powder for intravenous infusion	53007553/20.1.1/0075Approved 21 February 2023	Registered	S4	PI PIL
Tacyl EACH VIAL CONTAINS TIGECYCLINE 50,0 mg	50,0 mgSterile powder for solution for intravenous infusion	53063053/20.1.1/0630Approved 13 September 2022	Cancelled	S4	PI PIL
Cytagil iv EACH VIAL CONTAINS TIGECYCLINE 50,0 mg	50 mgPowder for solution for infusion.	53071553/20.1.1/0715Approved 25 April 2023	Registered	S4	PI PIL
Gaticil iv iv EACH VIAL CONTAINS TIGECYCLINE 50,0 mg	Not listed	530716.71553/20.1.1/0716.715	Cancelled	S4	None
Rubicil EACH VIAL CONTAINS TIGECYCLINE 50,0 mg	Not listed	53073053/20.1.1/0730	Registered	S4	None
Tigebax EACH VIAL CONTAINS TIGECYCLINE 50,0 mg	Not listed	54016554/20.1.1/0165	Registered	S4	None
Tigecycline adco EACH VIAL CONTAINS TIGECYCLINE 50,0 mg	50 mgSterile powder for solution for intravenous infusion	55075055/20.1.1/0750Approved 9 May 2023	Registered	S4	PI PIL
Tizeg EACH 10 ml CONTAINS 50,0 mg OF TIGECYCLINE	50 mgPowder for solution for infusion	56053156/20.1.1/0531Approved 31 January 2025	Registered	S4	PI PIL
Tigejex EACH VIAL CONTAINS: TIGECYCLINE 50,0 mg	50 mgLyophilised powder for injection	58001558/20.1.1/0015Approved 9 June 2026	Registered	S4	PI PIL
Tygiv EACH VIAL CONTAINS: TIGECYCLINE 50,0 mg	50 mgSterile powder for solution for infusion	59042359/20.1.1/0423Approved 21 April 2026	Registered	S4	PI PIL
Tyclin EACH VIAL CONTAINS: TIGECYCLINE 50,0 mg	50 mgSterile powder for solution for infusion	590424.42359/20.1.1/0424.423Approved 21 April 2026	Registered	S4	PI PIL
Tygacil EACH 5,0 ml VIAL CONTAINS TIGECYCLINE 50,0 mg	50mg / 5mlInfusion	A400230A40/20.1.1/0230Approved 20 October 2019	Registered	S4	PI

Regulatory status

Where S4 sits on the scale

S0S1S2S3S4S5S6S7S8

Prescription-only medicine.

Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S4, read from the product's PI-PIL leaflet.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Tigecycline

S4: Tigecycline
Consolidated Schedules 06 July 2026, line 8211

Pharmacological class: Broad and medium spectrum antibiotics. (class 20.1.1)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

Tigecycline 50 MG pfizer, Pfizer Laboratories (Pty) Ltd is scheduled S4 in its official SAHPRA documents, read with 90% confidence.

Professional information (PI)For healthcare professionalsTigecycline 50 MG pfizer, Pfizer Laboratories (Pty) Ltd Patient information leaflet (PIL)For patients and carersTigecycline 50 MG pfizer, Pfizer Laboratories (Pty) Ltd

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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