Tadalafil

Sold as Cialis, Ciavor, Incraflo, Tadalafil viatris, Tadalafil DYNA, Talvior, Tidalvor, Xpergo, Sentalis, Talegria, Ciatad, Actafil, Alemfil, Tadalafil biotech, Lidiax, Tadalafil cipla, Caverfil, Teldesel, Tadalafil, Tidalis, Fortad, Dysrect, Tadalafil unicorn, Tadalafil glenmark, Amotad, Taglenfil, Tadalafil unimed, Cydalatrin, Afilat, Filoryx, Teredys

C₂₂H₁₉N₃O₄389.40 g/mol

(2R,8R)-2-(1,3-Benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione

Drag to rotate. Structure from PubChem CID 110635.

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Registration

Applicants: 23
Registrations: 67
Schedule source: Consolidated Schedules 06 July 2026

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Eli Lilly (S.A.) (Pty) Ltd1 of 3 cancelled	Cialis	2,5, 5mg	360384, 410644, 410645	S4	PI PIL
Acino Pharma (Pty) LtdCertificate held by Eli Lilly (S.A.) (Pty) Ltd	Ciavor	5mg, 20 mg	360385, 480657	S4	PI PIL
Smart Pharmaceuticals (Pty) Ltd	Incraflo	20 mg	480034	S4	PI PIL
Viatris Healthcare (Pty) Ltd	Tadalafil viatris	5 mg	481100	S4	None
Viatris South Africa (Pty) Ltd	Tadalafil viatris	20 mg	481101	S4	None
Pharma Dynamics (Pty) Ltd	Tadalafil DYNA	5 mg, 20 mg	490285, 490286	S4	None
Forrester Pharma (Pty) Ltd	Talvior	5, 20	490785, 500661	S4	None
Aurogen South Africa (Pty) Ltd	Tidalvor, Xpergo	5 MG, 20 MG	490992, 490993, 490994, 490995	S4	None
Macleods Pharmaceuticals SA (Pty) Ltd	Sentalis	5 MG, 20 MG	491147, 491148	S4	None
Adcock ingram limited	Talegria	5, 20	491196, 491197	S4	None
Ranbaxy Pharmaceutical (Pty) LtdCertificate held by Ranbaxy Pharmaceuticals (Pty) LtdCancelled	Ciatad	5, 20	500010, 500011	S4	PI PIL
Actor Pharma (Pty) Ltd - Applicant	Actafil, Alemfil	5 MG, 20 MG	500046, 500047, 500048.046, 500049.047	S4	None
Biotech Laboratories (Pty) Ltd	Tadalafil biotech	5, 20	500654, 500655	S4	None
Ranbaxy (SA) (Pty) LtdCertificate held by Ranbaxy Pharmaceuticals (Pty) Ltd	Lidiax	5, 20	510014, 510015	S4	PI PIL
Cipla Medpro (Pty) LtdCertificate held by Cipla Medpro (Pty) Ltd.	Tadalafil cipla, Caverfil	5, 5 mg/ 20 mg, 20	510032, 510033, 510034.032, 510035.033	S4	PI PIL
Austell Pharmaceuticals (Pty) Ltd	Teldesel, Tadalafil	5 MG, 10 MG, 20 MG	510279, 510280, 510281, 510282.279, 510283.28, 510284.281	S4	None
Innovata pharmaceuticals4 of 6 cancelled	Tidalis, Fortad, Dysrect	5 MG, 20 MG	510390, 510391, 510392.39, 510393.391, 519004, 519005	S4	None
Unicorn Pharmaceuticals (Pty) Ltd	Tadalafil unicorn	2,5mg/5mg/20mg	520459, 520468, 520470	S4	PI PIL
Glenmark Pharmaceuticals South Africa (Pty) Ltd	Tadalafil glenmark, Taglenfil	5 mg, 10 mg, 20 mg	54/7.1.5/0048.044, 540042, 540043, 540044, 540046.042, 540047.043	S4	None
Ruby Pharmaceuticals (Pty) Ltd	Amotad	5, 20	540032, 540033	S4	PI PIL
Unimed Healthcare (Pty) Ltd	Tadalafil unimed	5, 20	550728, 550729	S4	None
Trinity Pharma (Pty) Ltd	Cydalatrin, Afilat, Filoryx	5, 20	560474, 560475, 560476.474, 560477.475, 5604780474, 560479.475	S4	None
Jubilant Pharma SA (Pty) Ltd	Teredys	5, 20	570381, 570382	S4	None

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Cialis EACH TABLET CONTAINS TADALAFIL 20,0 mg	Not listed	36038436/7.1.5/0384	Registered	S4	None
Ciavor 20 EACH TABLET CONTAINS TADALAFIL 20,0 mg	20 mgFilm-coated tablets.	36038536/7.1.5/0385Approved 15 March 2013	Registered	S4	PI PIL
Cialis 5 EACH TABLET CONTAINS TADALAFIL 5,0 mg	5mgFilm coated tablets	41064441/7.1.5/0644Approved 20 November 2025	Registered	S4	PI PIL
Cialis 2,5 EACH TABLET CONTAINS TADALAFIL 2,5 mg	2,5	41064541/7.1.5/0645	Cancelled	S4	None
Incraflo 20 MG EACH TABLET CONTAINS TADALAFIL 20,0 mg	20 mgTablet	48003448/7.1.5/0034Approved 17 October 2023	Registered	S4	PI PIL
Ciavor 5	5mgFilm coated talet	48065748/7.1.5/0657Approved 11 November 2024	Registered	S4	PI PIL
Tadalafil 5 MG viatris Each tablet contains :TADALAFIL 5,0 mg	5 mg	48110048/7.1.5/1100	Registered	S4	None
Tadalafil 20 MG viatris Each tablet contains :TADALAFIL 20,0 mg	20 mg	48110148/7.1.5/1101	Registered	S4	None
Tadalafil 5 MG DYNA EACH TABLET CONTAINS: TADALAFIL 5,0 mg	5 mg	49028549/7.1.5/0285	Registered	S4	None
Tadalafil 20 MG DYNA Each tablet contains TADALAFIL 20,0 mg	20 mg	49028649/7.1.5/0286	Registered	S4	None
Talvior 20 EACH TABLET CONTAINS :TADALAFIL 20,0 mg	20	49078549/7.1.5/0785	Registered	S4	None
Tidalvor 5 MG Each tablet contains TADALAFIL 5,0 mg	5 MG	49099249/7.1.5/0992	Registered	S4	None
Tidalvor 20 MG Each tablet contains TADALAFIL 20,0 mg	20 MG	49099349/7.1.5/0993	Registered	S4	None
Xpergo 5 MG Each tablet contains TADALAFIL 5,0 mg	5 MG	49099449/7.1.5/0994	Registered	S4	None
Xpergo 20 MG Each tablet contains TADALAFIL 20,0 mg	20 MG	49099549/7.1.5/0995	Registered	S4	None
Sentalis 5 MG Each tablet contains TADALAFIL 5,0 mg	5 MG	49114749/7.1.5/1147	Registered	S4	None
Sentalis 20 MG Each tablet contains TADALAFIL 20,0 mg	20 MG	49114849/7.1.5/1148	Registered	S4	None
Talegria 5 Each tablet contains TADALAFIL 5,0 mg	5	49119649/7.1.5/1196	Registered	S4	None
Talegria 20 Each tablet contains TADALAFIL 20,0 mg	20	49119749/7.1.5/1197	Registered	S4	None
Ciatad 5 Each tablet contains TADALAFIL 5,0 mg	5Film coated tablets.	50001050/7.1.5/0010Approved 12 July 2022	Cancelled	S4	PI PIL
Ciatad 20 Each tablet contains TADALAFIL 20,0 mg	20Film coated tablets.	50001150/7.1.5/0011Approved 12 July 2022	Cancelled	S4	PI PIL
Actafil 5 MG Each tablet contains TADALAFIL 5,0 mg	5 MG	50004650/7.1.5/0046	Registered	S4	None
Actafil 20 MG Each tablet contains TADALAFIL 20,0 mg	20 MG	50004750/7.1.5/0047	Registered	S4	None
Alemfil 5 MG Each tablet contains TADALAFIL 5,0 mg	5 MG	500048.04650/7.1.5/0048.46	Registered	S4	None
Alemfil 20 MG Each tablet contains TADALAFIL 20,0 mg	20 MG	500049.04750/7.1.5/0049.47	Registered	S4	None
Tadalafil 5 biotech Each tablet contains TADALAFIL 5,0 mg	5	50065450/7.1.5/0654	Registered	S4	None
Tadalafil 20 biotech Each tablet contains TADALAFIL 20,0 mg	20	50065550/7.1.5/0655	Registered	S4	None
Talvior 5 EACH TABLET CONTAINS :TADALAFIL 5,0 mg	5	50066150/7.1.5/0661	Registered	S4	None
Lidiax 5 Each tablet contains TADALAFIL 5,0 mg	5Film coated tablets	51001451/7.1.5/0014Approved 4 August 2023	Registered	S4	PI PIL
Lidiax 20 Each tablet contains TADALAFIL 20,0 mg	20Film coated tablets	51001551/7.1.5/0015Approved 4 August 2023	Registered	S4	PI PIL
Tadalafil 5 cipla Each tablet contains TADALAFIL 5,0 mg	5Film-coated tablets	51003251/7.1.5/0032Approved 16 January 2026	Registered	S4	PI PIL
Tadalafil 20 cipla Each tablet contains TADALAFIL 20,0 mg	20Film-coated tablets	51003351/7.1.5/0033Approved 16 January 2026	Registered	S4	PI PIL
Caverfil 5 Each tablet contains TADALAFIL 5,0 mg	5 mg/ 20 mgFilm-coated tablets	510034.03251/7.1.5/0034.032Approved 16 January 2026	Registered	S4	PI PIL
Caverfil 20 Each tablet contains TADALAFIL 20,0 mg	5 mg/ 20 mgFilm-coated tablets	510035.03351/7.1.5/0035.033Approved 16 January 2026	Registered	S4	PI PIL
Teldesel 5 MG tablets Each tablet contains TADALAFIL 5,0 mg	5 MGTablets	51027951/7.1.5/0279	Registered	S4	None
Teldesel 10 MG tablets Each tablet contains TADALAFIL 10,0 mg	10 MGTablets	51028051/7.1.5/0280	Registered	S4	None
Teldesel 20 MG tablets Each tablet contains TADALAFIL 20,0 mg	20 MGTablets	51028151/7.1.5/0281	Registered	S4	None
Tadalafil 5 MG tablets Each tablet contains TADALAFIL 5,0 mg2	5 MGTablets	510282.27951/7.1.5/0282.279	Registered	S4	None
Tadalafil 10 MG tablets Each tablet contains TADALAFIL 10,0 mg	10 MGTablets	510283.2851/7.1.5/0283.280	Registered	S4	None
Tadalafil 20 MG tablets Each tablet contains TADALAFIL 20,0 mg	20 MGTablets	510284.28151/7.1.5/0284.281	Registered	S4	None
Tidalis 5 Each tablet contains TADALAFIL 5,0 mg	5	51039051/7.1.5/0390	Registered	S4	None
Tidalis 20 Each tablet contains TADALAFIL 20,0 mg	20	51039151/7.1.5/0391	Registered	S4	None
Fortad 5 MG Each tablet contains TADALAFIL 5,0 mg	5 MG	510392.3951/7.1.5/0392.390	Cancelled	S4	None
Fortad 20 MG Each tablet contains TADALAFIL 20,0 mg	20 MG	510393.39151/7.1.5/0393.391	Cancelled	S4	None
Dysrect 5 Each tablet contains TADALAFIL 5,0 mg	5	51900451/7.1.5/9004	Cancelled	S4	None
Dysrect 20 Each tablet contains TADALAFIL 20,0 mg	20	51900551/7.1.5/9005	Cancelled	S4	None
Tadalafil 5 unicorn	2,5mg/5mg/20mgFilm-coated tablets	52045952/7.1.5/0469Approved 7 June 2024	Registered	S4	PI PIL
Tadalafil 2,5 unicorn	2,5mg/5mg/20mgFilm-coated tablets	52046852/7.1.5/0468Approved 7 June 2024	Registered	S4	PI PIL
Tadalafil 20 unicorn	2,5mg/5mg/20mgFilm-coated tablets	52047052/7.1.5/0470Approved 7 June 2024	Registered	S4	PI PIL
Tadalafil 20 MG glenmark EACH TABLET CONTAINS TADALAFIL 20,0 mg	20 mg	54/7.1.5/0048.044	Registered	S4	None
Amotad 5 TADALAFIL	5Film-coated tablets	54003254/7.1.5/0032Approved 15 February 2024	Registered	S4	PI PIL
Amotad 20 TADALAFIL	20Film-coated tablets	54003354/7.1.5/0033Approved 15 February 2024	Registered	S4	PI PIL
Taglenfil 5 MG EACH TABLET CONTAINS TADALAFIL 5,0 mg	5 mg	54004254/7.15/0042	Registered	S4	None
Taglenfil 10 MG EACH TABLET CONTAINS TADALAFIL 10,0 mg	10 mg	54004354/7.1.5/0043	Registered	S4	None
Taglenfil 20 MG EACH TABLET CONTAINS TADALAFIL 20,0 mg	20 mg	54004454/7.1.5/0044	Registered	S4	None
Tadalafil 5 MG glenmark EACH TABLET CONTAINS TADALAFIL 5,0 mg	5 mg	540046.04254/7.1.5/0046.042	Registered	S4	None
Tadalafil 10 MG glenmark EACH TABLET CONTAINS TADALAFIL 10,0 mg	10 mg	540047.04354/7.1.5/0047.043	Registered	S4	None
Tadalafil 5 unimed EACH TABLET CONTAINS TADALAFIL 5,0 mg	5	55072855/7.1.5/0728	Registered	S4	None
Tadalafil 20 unimed EACH TABLET CONTAINS TADALAFIL 20,0 mg	20	55072955/7.1.5/0729	Registered	S4	None
Cydalatrin 5 EACH TABLET CONTAINS TADALAFIL 5,0 mg	5	56047456/7.1.5/0474	Registered	S4	None
Cydalatrin 20 EACH TABLET CONTAINS TADALAFIL 20,0 mg	20	56047556/7.1.5/0475	Registered	S4	None
Afilat 5 EACH TABLET CONTAINS TADALAFIL 5,0 mg	5	560476.47456/7.1.5/0476.474	Registered	S4	None
Afilat 20 EACH TABLET CONTAINS TADALAFIL 20,0 mg	20	560477.47556/7.1.5/0477.475	Registered	S4	None
Filoryx 5 EACH TABLET CONTAINS TADALAFIL 5,0 mg	5	560478047456/7.1.5/0478.474	Registered	S4	None
Filoryx 20 EACH TABLET CONTAINS TADALAFIL 20,0 mg	20	560479.47556/7.1.5/0479.475	Registered	S4	None
Teredys 5 Each Tablet contains: Tadalafil 5,0 mg	5	57038157/7.1.5/0381	Registered	S4	None
Teredys 20 Each Tablet contains: Tadalafil 20,0 mg	20	57038257/7.1.5/0382	Registered	S4	None

Regulatory status

Where S4 sits on the scale

S0S1S2S3S4S5S6S7S8

Prescription-only medicine.

Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S4, matched to the Consolidated Schedules by ingredient, confidence high.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Tadalafil

S4: Tadalafil
Consolidated Schedules 06 July 2026, line 8086

Pharmacological class: Vasodilators - peripheral. (class 7.1.5)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

Ciavor 20, Acino Pharma (Pty) Ltd is scheduled S4 in its official SAHPRA documents, read with 90% confidence.

Professional information (PI)For healthcare professionalsCiavor 20, Acino Pharma (Pty) Ltd Patient information leaflet (PIL)For patients and carersCiavor 20, Acino Pharma (Pty) Ltd

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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