Spironolactone
Sold as Spironolactone accord, * spironolactone unicorn, Jubactone fc, Spirona, Spirozy, Aldactone, Spiractin, Spironolactone kiara
S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-3,5'-dioxospiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,2'-oxolane]-7-yl] ethanethioate
Drag to rotate. Structure from PubChem CID 5833.
Background
Registration
- Applicants
- 7
- Registrations
- 15
- Schedule source
- Consolidated Schedules 06 July 2026
Applicants and registrations
| Applicant | Brands | Dosages | Registrations | Schedule | Leaflets |
|---|---|---|---|---|---|
| Accord Healthcare (Pty) Ltd | Spironolactone accord | 25 mg, 100mg | 550776, 550777 | S3 | None |
| Jubilant Pharma SA (Pty) Ltd | * spironolactone unicorn, Jubactone fc | 25 mg, 100 mg | 570344, 570345, 570346.344, 570347.345 | S3 | None |
| Zydus Healthcare (Pty) Ltd | Spirona, Spirozy | 25, 100 | 590330, 590331, 590332.330, 590333.331 | S3 | None |
| Pfizer Laboratories (Pty) Ltd | Aldactone | 100 | H0002 | S3 | None |
| Pharmacia South Africa (Pty) Ltd | Aldactone | 25 | H1941 | S3 | None |
| Pharmacare limited û woodmeadCertificate held by Pharmacare limited | Spiractin | 25 mg, 100 | L0186, U0052 | S3 | PI |
| Kiara Health (Pty) Ltd | Spironolactone kiara | 25 | Q0070 | S3 | None |
Variants
| Product | Strength and form | Registration | Status | Schedule | Leaflets |
|---|---|---|---|---|---|
| Spironolactone 25 MG accord EACH TABLET CONTAINS SPIRONOLACTONE 25,0 mg | 25 mg | 55077655/18.1/0776 | Registered | S3 | None |
| Spironolactone 100mg accord EACH TABLET CONTAINS SPIRONOLACTONE 100,0 mg | 100mg | 55077755/18.1/0777 | Old Medicine | S3 | None |
| * spironolactone 25 unicorn EACH TABLET CONTAINS: SPIRONOLACTONE 25,0 mg | 25 | 57034457/18.1/0344 | Registered | S3 | None |
| * spironolactone 100 unicorn EACH TABLET CONTAINS: SPIRONOLACTONE 100,0 mg | 100 | 57034557/18.1/0345 | Registered | S3 | None |
| Jubactone fc 25 MG EACH TABLET CONTAINS SPIRONOLACTONE 25,0 mg | 25 mg | 570346.34457/18.1/0346.344 | Registered | S3 | None |
| Jubactone fc 100 MG EACH TABLET CONTAINS SPIRONOLACTONE 100,0 mg | 100 mg | 570347.34557/18.1/0347.345 | Registered | S3 | None |
| Spirona 25 EACH TABLET CONTAINS: SPIRONOLACTONE 25,0 mg | 25 | 59033059/18.1/0330 | Registered | S3 | None |
| Spirona 100 EACH TABLET CONTAINS: SPIRONOLACTONE 100,0 mg | 100 | 59033159/18.1/0331 | Registered | S3 | None |
| Spirozy 25 EACH TABLET CONTAINS: SPIRONOLACTONE 25,0 mg | 25 | 590332.33059/18.1/0332.330 | Registered | S3 | None |
| Spirozy 100 EACH TABLET CONTAINS: SPIRONOLACTONE 100,0 mg | 100 | 590333.33159/18.1/0333.331 | Registered | S3 | None |
| Aldactone 100 EACH TABLET CONTAINS SPIRONOLACTONE 100 mg | 100 | H0002H/18.1/2 | Registered | S3 | None |
| Aldactone 25 EACH TABLET CONTAINS SPIRONOLACTONE A 25 mg | 25 | H1941 | Old Medicine | S3 | None |
| Spiractin EACH TABLET CONTAINS SPIRONOLACTONE 25 mg | 25 mgTablets | L0186L/18.1/186Approved 15 February 1979 | Registered | S3 | PI |
| Spironolactone 25 kiara EACH TABLET CONTAINS SPIRONOLACTONE 25 MG | 25 | Q0070Q/18.1/70 | Registered | S3 | None |
| Spiractin 100 tablets EACH TABLET CONTAINS SPIRONOLACTONE 100 mg | 100Tablets | U0052U/18.1/52 | Registered | S3 | None |
Regulatory status
Where S3 sits on the scale
Needs a doctor's prescription, dispensed by a pharmacist.
Schedule 3 medicines can only be sold on a prescription from an authorised prescriber, such as a doctor or dentist. A pharmacist dispenses the medicine once they have the written prescription, or a verbal instruction from a prescriber they know. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.
Schedule S3, matched to the Consolidated Schedules by ingredient, confidence high.
Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.
Consolidated Schedules listings for Spironolactone
S3: Spironolactone
Consolidated Schedules 06 July 2026, line 4265
Pharmacological class: Diuretics. (class 18.1)
This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.
SAHPRA documents
Schedule Verification
Spiractin, Pharmacare limited û woodmead is scheduled S3 in its official SAHPRA documents, read with 90% confidence.
These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.