Simvastatin

Sold as Zocor, Simvacor, Adco-simvastatin, Adco simvastatin, Lipidex, Simcard, Unisim, Simvotin, Aspen simvastatin, Simvastatin unimed, Novatin, Choleste, Zysim, Simchol, Simvastatin DYNA, Cipla simvastatin, Simvastatin austell, Apex simvastatin, *Simvastatin MPC, Pharma dynamics simvastatin, Cipla-simvastatin

C₂₅H₃₈O₅418.60 g/mol

[(1S,3R,7S,8S,8AR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoate

Drag to rotate. Structure from PubChem CID 54454.

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Registration

Applicants: 16
Registrations: 57
Schedule source: Consolidated Schedules 06 July 2026

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Organon South Africa (Pty) LtdCancelled	Zocor	10, 20, 40	310447, W0350, W0351	S4	None
Pharma Dynamics (Pty) Ltd2 of 5 cancelled	Simvacor, Simvastatin DYNA, Pharma dynamics simvastatin	10, 20 mg, 40 mg, 80	350237, 350238, 410833, A390131, A390132	S4	PI PIL
Adcock ingram limited	Adco-simvastatin, Adco simvastatin	10 mg, 20 mg, 40 mg	350277, 350278, 350279	S4	None
Oethmaan Biosims (Pty) Ltd	Lipidex	10, 20	360213, 360214	S4	None
Ipharma (Pty) LtdCertificate held by Ipharma (Pty) Ltd.	Simcard	10, 20	360215, 360216	S4	PI PIL
Unimed Healthcare (Pty) Ltd	Unisim, Simvastatin unimed	10 mg, 20 mg, 40 mg	360370, 360371, 360372, 380276, 380334, 380335	S4	PI PIL
Ranbaxy Pharmaceutical (Pty) Ltd	Simvotin	10, 20, 40	360373, 360374, 360375	S4	None
Pharmacare limited û woodmead2 of 3 cancelled	Aspen simvastatin	10 mg, 20 mg, 40 mg	370335, 370336, 370337	S4	None
Novagen Pharma (Pty) LtdCancelled	Novatin	5, 10, 20, 40, 80	410381, 410382, 410383, 410384, 410385	S4	None
Unicorn Pharmaceuticals (Pty) Ltd	Choleste	10, 20, 40	410391, 410392, 410393	S4	None
Zydus Healthcare (Pty) LtdCancelled	Zysim	10, 20, 40, 80	410666, 410667, 410668, 410669	S4	None
Aurogen South Africa (Pty) Ltd	Simchol	5 mg, 10 mg, 20 mg, 40 mg, 80 mg	410800, 410801, 410802, 410803, 410804	S4	None
Cipla Medpro (Pty) Ltd	Cipla simvastatin, Cipla-simvastatin	10, 20, 40, 80	A380370, A380371, A400397, A400398	S4	None
Austell Pharmaceuticals (Pty) Ltd	Simvastatin austell	10 mg, 20 mg, 40 mg	A380477, A380478, A380479	S4	None
Camox Pharmaceuticals (Pty) LtdCancelled	Apex simvastatin	10 mg, 20 mg, 40 mg	A380678, A380679, A380680	S4	None
Mothopo pharma chem	*Simvastatin MPC	10 mg, 20 mg, 40 mg	A380707, A380708, A380709	S4	None

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Zocor 40 EACH TABLET CONTAINS SIMVASTATIN 40,0 mg	40	31044731/7.5/0447	Cancelled	S4	None
Simvacor 10 EACH TABLET CONTAINS SIMVASTATIN 10,0 mg	10Film coated tablets.	35023735/7.5/0237Approved 14 January 2026	Registered	S4	PI PIL
Simvacor 20 MG EACH TABLET CONTAINS SIMVASTATIN 20,0 mg	20 mg	35023835/7.5/0238	Registered	S4	None
Adco-simvastatin 10 MG EACH TABLET CONTAINS SIMVASTATIN 10,0 mg	10 mg	35027735/7.5/0277	Registered	S4	None
Adco simvastatin 20 MG EACH TABLET CONTAINS SIMVASTATIN 20,0 mg	20 mg	35027835/7.5/0278	Registered	S4	None
Adco-simvastatin 40 MG EACH TABLET CONTAINS SIMVASTATIN 40,0 mg	40 mg	35027935/7.5/0279	Registered	S4	None
Lipidex 10 EACH TABLET CONTAINS SIMVASTATIN 10,0 mg	10	36021336/7.5/0213	Registered	S4	None
Lipidex 20 EACH TABLET CONTAINS SIMVASTATIN 20,0 mg	20	36021436/7.5/0214	Registered	S4	None
Simcard 10 EACH TABLET CONTAINS SIMVASTATIN 10,0 mg	10Film-coated tablets.	36021536/7.5/0215Approved 26 July 2021	Registered	S4	PI PIL
Simcard 20 EACH TABLET CONTAINS SIMVASTATIN 20,0 mg	20Film-coated tablets.	36021636/7.5/0216Approved 26 July 2021	Registered	S4	PI PIL
Unisim 10 EACH TABLET CONTAINS SIMVASTATIN 10,0 mg	10Film-coated tablets.	36037036/7.5/0370Approved 22 June 2023	Registered	S4	PI PIL
Unisim 20 EACH TABLET CONTAINS SIMVASTATIN 20,0 mg	20Film-coated tablets.	36037136/7.5/0371Approved 22 June 2023	Registered	S4	PI PIL
Unisim 40 EACH TABLET CONTAINS SIMVASTATIN 40,0 mg	40Film-coated tablets.	36037236/7.5/0372Approved 22 June 2023	Registered	S4	PI PIL
Simvotin 10 tablets EACH TABLET CONTAINS SIMVASTATIN 10,0 mg	10Tablets	36037336/7.5/0373	Registered	S4	None
Simvotin 20 tablets EACH TABLET CONTAINS: SIMVASTATIN 20,0 mg	20Tablets	36037436/7.5/0374	Registered	S4	None
Simvotin 40 tablets EACH TABLET CONTAINS: SIMVASTATIN 40,0 mg	40Tablets	36037536/7.5/0375	Registered	S4	None
Aspen simvastatin 10 MG EACH TABLET CONTAINS SIMVASTATIN 10,0 mg	10 mg	37033537/7.5/0335	Cancelled	S4	None
Aspen simvastatin 20 MG EACH TABLET CONTAINS SIMVASTATIN 20,0 mg	20 mg	37033637/7.5/0336	Cancelled	S4	None
Aspen simvastatin 40 MG EACH TABLET CONTAINS SIMVASTATIN 40,0 mg	40 mg	37033737/7.5/0337	Registered	S4	None
Simvastatin 40 MG unimed EACH TABLET CONTAINS SIMVASTATIN 40,0 mg	40 mg	38027638/7.5/0276	Registered	S4	None
Simvastatin 10 MG unimed EACH TABLET CONTAINS SIMVASTATIN 10,0 mg	10 mg	38033438/7.5/0334	Registered	S4	None
Simvastatin 20 MG unimed EACH TABLET CONTAINS SIMVASTATIN 20,0 mg	20 mg	38033538/7.5/0335	Registered	S4	None
Novatin 5 EACH TABLET CONTAINS :SIMVASTATIN 5,0 mg	5	41038141/7.5/0381	Cancelled	S4	None
Novatin 10 EACH TABLET CONTAINS S:IMVASTATIN 10,0 mg	10	41038241/7.5/0382	Cancelled	S4	None
Novatin 20 EACH TABLET CONTAINS SIMVASTATIN 20,0 mg	20	41038341/7.5/0383	Cancelled	S4	None
Novatin 40 EACH TABLET CONTAINS :SIMVASTATIN 40,0 mg	40	41038441/7.5/0384	Cancelled	S4	None
Novatin 80 EACH TABLET CONTAINS SIMVASTATIN 80,0 mg	80	41038541/7.5/0385	Cancelled	S4	None
Choleste 10 EACH TABLET CONTAINS SIMVASTATIN 10,0 mg	10	41039141/7.5/0391	Registered	S4	None
Choleste 20 EACH TABLET CONTAINS SIMVASTATIN 20,0 mg	20	41039241/7.5/0392	Registered	S4	None
Choleste 40 EACH TABLET CONTAINS SIMVASTATIN 40,0 mg	40	41039341/7.5/0393	Registered	S4	None
Zysim 10 EACH TABLET CONTAINS SIMVASTATIN 10,0 mg	10	41066641/7.5/0666	Cancelled	S4	None
Zysim 20 EACH TABLET CONTAINS SIMVASTATIN 20,0 mg	20	41066741/7.5/0667	Cancelled	S4	None
Zysim 40 EACH TABLET CONTAINS SIMVASTATIN 40,0 mg	40	41066841/7.5/0668	Cancelled	S4	None
Zysim 80 EACH TABLET CONTAINS SIMVASTATIN 80,0 mg	80	41066941/7.5/0669	Cancelled	S4	None
Simchol 5 MG EACH TABLET CONTAINS SIMVASTATIN 5,0 mg	5 mg	41080041/7.5/0800	Registered	S4	None
Simchol 10 MG EACH TABLET CONTAINS SIMVASTATIN 10,0 mg	10 mg	41080141/7.5/0801	Registered	S4	None
Simchol 20 MG EACH TABLET CONTAINS SIMVASTATIN 20,0 mg	20 mg	41080241/7.5/0802	Registered	S4	None
Simchol 40 MG EACH TABLET CONTAINS SIMVASTATIN 40,0 mg	40 mg	41080341/7.5/0803	Registered	S4	None
Simchol 80 MG EACH TABLET CONTAINS SIMVASTATIN 80,0 mg	80 mg	41080441/7.5/0804	Registered	S4	None
Simvastatin 80 DYNA EACH TABLET CONTAINS SIMVASTATIN 80,0 mg	80	41083341/7.5/0833	Cancelled	S4	None
Cipla simvastatin 40 EACH TABLET CONTAINS SIMVASTATIN 40,0 mg	40	A380370A38/7.5/0370	Registered	S4	None
Cipla simvastatin 80 EACH TABLET CONTAINS SIMVASTATIN 80,0 mg	80	A380371A38/7.5/0371	Registered	S4	None
Simvastatin 10 MG austell EACH TABLET CONTAINS: SIMVASTATIN 10,0 mg	10 mg	A380477A38/7.5/0477	Registered	S4	None
Simvastatin 20 MG austell EACH TABLET CONTAINS :SIMVASTATIN 20,0 mg	20 mg	A380478A38/7.5/0478	Registered	S4	None
Simvastatin 40 MG austell EACH TABLET CONTAINS: SIMVASTATIN 40,0 mg	40 mg	A380479A38/7.5/0479	Registered	S4	None
Apex simvastatin 10 MG EACH TABLET CONTAINS SIMVASTATIN 10,0 mg	10 mg	A380678A38/7.5/0678	Cancelled	S4	None
Apex simvastatin 20 MG EACH TABLET CONTAINS SIMVASTATIN 20,0 mg	20 mg	A380679A38/7.5/0679	Cancelled	S4	None
Apex simvastatin 40 MG EACH TABLET CONTAINS SIMVASTATIN 40,0 mg	40 mg	A380680A38/7.5/0680	Cancelled	S4	None
*Simvastatin 10 MG MPC EACH TABLET CONTAINS :SIMVASTATIN 10,0 mg	10 mg	A380707A38/7.5/0707	Registered	S4	None
*Simvastatin 20 MG MPC EACH TABLET CONTAINS :SIMVASTATIN 20,0 mg	20 mg	A380708A38/7.5/0708	Registered	S4	None
*Simvastatin 40 MG MPC EACH TABLET CONTAINS :SIMVASTATIN 40,0 mg	40 mg	A380709A39/7.5/0709	Registered	S4	None
Pharma dynamics simvastatin 40 MG EACH TABLET CONTAINS SIMVASTATIN 40,0 mg	40 mg	A390131A39/7.5/0131	Cancelled	S4	None
Simvacor 40 MG EACH TABLET CONTAINS SIMVASTATIN 40,0 mg	40 mg	A390132A39/7.5/0132	Registered	S4	None
Cipla-simvastatin 10 EACH TABLET CONTAINS SIMVASTATIN 10,0 mg	10	A400397A40/7.5/0397	Registered	S4	None
Cipla simvastatin 20 EACH TABLET CONTAINS SIMVASTATIN 20,0 mg	20	A400398A40/7.5/0398	Registered	S4	None
Zocor 10 EACH TABLET CONTAINS SIMVASTATIN 10 mg	10	W0350W/7.5/350	Cancelled	S4	None
Zocor 20 EACH TABLET CONTAINS SIMVASTATIN 20 mg	20	W0351W/7.5/351	Cancelled	S4	None

Regulatory status

Where S4 sits on the scale

S0S1S2S3S4S5S6S7S8

Prescription-only medicine.

Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S4, matched to the Consolidated Schedules by ingredient, confidence high.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Simvastatin

S4: Simvastatin
Consolidated Schedules 06 July 2026, line 7936

Pharmacological class: Serum-cholesterol reducers. (class 7.5)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

Simvacor 10, Pharma Dynamics (Pty) Ltd is scheduled S4 in its official SAHPRA documents, read with 90% confidence.

Professional information (PI)For healthcare professionalsSimvacor 10, Pharma Dynamics (Pty) Ltd Patient information leaflet (PIL)For patients and carersSimvacor 10, Pharma Dynamics (Pty) Ltd

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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