Sertraline

Sold as Zoloft, Serlife, Tralidep, Serdep, Adco-zertra, Sermax, Sertraline unimed, Sertaline PD, Sertraline PD, Aspen sertraline, Sertraline unicorn, Sertraline austell, Sertra, Zylin, Dantrix, Merck-sertraline, Zosert, Arloft, Aurolift, Aysert

C₁₇H₁₇Cl₂N306.20 g/mol

(1S,4S)-4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine

Drag to rotate. Structure from PubChem CID 68617.

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Registration

Applicants: 16
Registrations: 33
Schedule source: Consolidated Schedules 06 July 2026

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Viatris Healthcare (Pty) Ltd	Zoloft	50 mg	320381	S5	PI PIL
Ranbaxy (SA) (Pty) LtdCertificate held by Ranbaxy Pharmaceuticals {Pty) Ltd	Serlife	50, 100	360272, 360273	S5	PI PIL
Arya Pharma (Pty) Ltd	Tralidep	50, 100	360274, 360275	S5	None
Cipla Medpro (Pty) Ltd	Serdep	50, 100	380020, A380617	S5	None
Adcock ingram limited	Adco-zertra	50, 100	380290, 380291	S5	None
Be-tabs Pharmaceuticals (Pty) LtdCancelled	Sermax	50, 100	410209, 410210	S5	None
Unimed Healthcare (Pty) Ltd	Sertraline unimed	50, 100 mg	410584, 410585	S5	None
Pharma Dynamics (Pty) Ltd	Sertaline PD, Sertraline PD	50 mg, 100 mg	430339, 430340	S5	None
Pharmacare limited û woodmeadCancelled	Aspen sertraline	50 mg, 100 mg	A380482, A380483	S5	None
Austell Pharmaceuticals (Pty) Ltd	Sertraline unicorn, Sertraline austell	50 mg, 100 mg	A380618, A380619, A390286, A390287	S5	None
Viatris South Africa (Pty) Ltd	Sertra	50 mg	A390308	S5	PI PIL
Zydus Healthcare (Pty) Ltd	Zylin, Aysert	50	A390596, A400662	S5	None
Merck Generics Rsa (Pty) Ltd	Dantrix, Merck-sertraline	50, 100	A390635, A390636, A400085, A400086	S5	None
MSQ Pharma (Pty) Ltd	Zosert	50	A400483	S5	None
Arrow Pharma South Africa (Pty) Ltd	Arloft	50, 100	A400503, A400504	S5	None
Aurogen South Africa (Pty) Ltd	Aurolift	50 mg, 100 mg	A400654, A400655	S5	None

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Zoloft tablets 50 MG EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 50,0 mg	50 mgTablets	32038132/1.2/0381Approved 13 March 2023	Registered	S5	PI PIL
Serlife 50 EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 50,0 mg	50Each film coated tablet	36027236/1.2/0272Approved 4 November 2022	Registered	S5	PI PIL
Serlife 100 EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 100,0 mg	100Each film coated tablet	36027336/1.2/0273Approved 4 November 2022	Registered	S5	PI PIL
Tralidep 50 EACH TABLET CONTAINS :SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 50,0 mg	50	36027436/1.2/0274	Registered	S5	None
Tralidep 100 EACH TABLET CONTAINS: SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 100,0 mg	100	36027536/1.2/0275	Registered	S5	None
Serdep-50 EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 50,0 mg	50	38002038/1.2/0020	Registered	S5	None
Adco-zertra 50 EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 50,0 mg	50	38029038/1.2/0290	Registered	S5	None
Adco-zertra 100 EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 100,0 mg	100	38029138/1.2/0291	Registered	S5	None
Sermax 50 EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 50,0 mg	50	41020941/1.2/0209	Cancelled	S5	None
Sermax 100 EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 100,0 mg	100	41021041/1.2/0210	Cancelled	S5	None
Sertraline 50 unimed EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 50,0 mg	50	41058441/1.2/0584	Registered	S5	None
Sertraline 100 MG unimed EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 100,0 mg	100 mg	41058541/1.2/0585	Registered	S5	None
Sertaline 50 MG PD EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 50,0 mg	50 mg	43033943/1.2/0339	Registered	S5	None
Sertraline 100 MG PD EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 100,0 mg	100 mg	43034043/1.2/0340	Registered	S5	None
Aspen sertraline 50 MG EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 50,0 mg	50 mg	A380482A38/1.2/0482	Cancelled	S5	None
Aspen sertraline 100 MG EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE 100,0 mg	100 mg	A380483A38/1.2/0483	Cancelled	S5	None
Serdep 100 EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 100,0 mg	100	A380617A38/1.2/0617	Registered	S5	None
Sertraline 50 MG unicorn EACH TABLET CONTAINS: SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 50,0 mg	50 mg	A380618A38/1.2/0618	Registered	S5	None
Sertraline 100 MG unicorn EACH TABLET CONTAINS: SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 100,0 mg	100 mg	A380619A38/1.2/0619	Registered	S5	None
Sertraline 50 MG austell EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 50,0 mg	50 mg	A390286A39/1.2/0286	Registered	S5	None
Sertraline 100 MG austell EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 100,0 mg	100 mg	A390287A39/1.2/0287	Registered	S5	None
Sertra tablets 50 MG EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 50,0 mg	50 mgTablet	A390308A39/1.2/0308Approved 29 September 2023	Registered	S5	PI PIL
Zylin 50 EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 50,0 mg	50	A390596A39/1.2/0596	Registered	S5	None
Dantrix 50 EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 50,0 mg	50	A390635A39/1.2/0635	Registered	S5	None
Dantrix 100 EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 100,0 mg	100	A390636A39/1.2/0636	Registered	S5	None
Merck-sertraline 50 EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 50,0 mg	50	A400085A40/1.2/0085	Registered	S5	None
Merck-sertraline 100 EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 100,0 mg	100	A400086A40/1.2/0086	Registered	S5	None
Zosert 50 EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 50,0 mg	50	A400483A40/1.2/0483	Registered	S5	None
Arloft 50 EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 50,0 mg	50	A400503A40/1.2/0503	Registered	S5	None
Arloft 100 EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 100,0 mg	100	A400504A40/1.2/0504	Registered	S5	None
Aurolift 50 MG EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 50,0 mg	50 mg	A400654A40/1.2/0654	Registered	S5	None
Aurolift 100 MG EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 100,0 mg	100 mg	A400655A40/1.2/0655	Registered	S5	None
Aysert 50 EACH TABLET CONTAINS SERTRALINE HYDROCHLORIDE EQUIVALENT TO SERTRALINE 50,0 mg	50	A400662A40/1.2/0662	Registered	S5	None

Regulatory status

Where S5 sits on the scale

S0S1S2S3S4S5S6S7S8

Prescription-only, with tighter controls on repeats.

Schedule 5 medicines need a prescription, and repeat dispensing is capped at six months in total; the prescriber must state upfront how many times, and at what intervals, it may be repeated. Extra limits apply to some uses: if it is being used for its anxiolytic, antidepressant, tranquillising or analgesic properties, it cannot be prescribed for longer than six months without a further consultation. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S5, matched to the Consolidated Schedules by ingredient, confidence high.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it.

Consolidated Schedules listings for Sertraline hydrochloride equivalent to sertraline

S5: Sertraline
Consolidated Schedules 06 July 2026, line 9691

Pharmacological class: Psychoanaleptics (antidepressants). (class 1.2)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Professional information (PI)For healthcare professionalsZoloft tablets 50 MG, Viatris Healthcare (Pty) Ltd Patient information leaflet (PIL)For patients and carersZoloft tablets 50 MG, Viatris Healthcare (Pty) Ltd

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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