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Sulfamethoxazole, trimethoprim (Septran, Septran Paediatric, Septran Paediatric Suspensin, Mezenol, Purbac Liquid, Purbac Adult, Purbac Paediatric, Septran Ds Tab, Purbac Double Strength, Purbac, Co-trimoxazole, Septran Forte)

Sulfamethoxazole, trimethoprim

Pharmacare limited û woodmead

S4

Registration

Applicant
Pharmacare limited û woodmead
Registrations
13
Schedule source
Consolidated Schedules 06 July 2026

Variants

ProductStrength and formRegistrationStatusScheduleLeaflets
Septran

EACH TABLET CONTAINS SULFAMETHOXAZOLE 400 mg TRIMETHOPRIM 80 mg

Not listedB0109B/20.2/109RegisteredS4None
Septran paediatric tablet

TABLET SULFAMETHOXAZOLE 100 MG TRIMETHOPRIM 20 MG

TabletB0110B/20.2/110RegisteredS4None
Septran paediatric suspensin

EACH 5 ml CONTAINS SULFAMETHOXAZOLE 200 mg TRIMETHOPRIM 40 mg

Not listedB0179B/20.2/179RegisteredS4None
Mezenol

EACH TABLET CONTAINS SULFAMETHOXAZOLE 400 MG TRIMETHOPRIM 80 MG

Not listedG0097G/20.1/97CancelledS4None
Purbac liquid

EACH 5 ml SUSPENSION CONTAINS SULFAMETHOXAZOLE 200 mg TRIMETHOPRIM 40 mg

Not listedG0099G/20.2/99RegisteredS4None
Purbac adult

EACH TABLET CONTAINS SULFAMETHOXAZOLE 400 MG TRIMETHOPRIM 80 MG

Not listedJ0339J/20.2/339RegisteredS4None
Purbac paediatric

EACH TABLET CONTAINS SULFAMETHOXAZOLE 100 mg TRIMETHOPRIM 20 mg

Not listedJ0340J/20.2/340RegisteredS4None
Purbac paediatric suspension

EACH 5 ML SUSPENSION CONTAINS SULFAMETHOXAZOLE 200 MG TRIMETHOPRIM 40 MG

SuspensionK0241K/20.2/241RegisteredS4None
Septran ds tab

EACH TABLET CONTAINS SULFAMETHOXAZOLE 800 mg TRIMETHOPRIM 160 mg

Not listedL0057L/20.2/0057RegisteredS4None
Purbac double strength

EACH TABLET CONTAINS SULFAMETHOXAZOLE 800 MG TRIMETHOPRIM 160 MG

Not listedL0295L/20.2/295RegisteredS4None
Purbac injection 5 ML

EACH 5 ml AMPOULE CONTAINS SULFAMETHOXAZOLE 400 mg TRIMETHOPRIM 80 mg

5 mlInjectionL0336L/20.2/336RegisteredS4None
Co-trimoxazole suspension

EACH 5 ml SUSPENSION CONTAINS SULFAMETHOXAZOLE 200 mg TRIMETHOPRIM 40 mg

SuspensionL0370L/20.2/370CancelledS4None
Septran suspension forte

EACH 5,0 ml SUSPENSION CONTAINS SULFAMETHOXAZOLE 400,0 mg TRIMETHOPRIM 80,0 mg

SuspensionP0175P/20.2/175RegisteredS4None

Regulatory status

Where S4 sits on the scale

Prescription-only medicine.

Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S4, matched to the Consolidated Schedules by ingredient, confidence medium.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Sulfamethoxazole, trimethoprim

  • S4: Sulfamethoxazole

    • except when registered in terms of the provisions of the Fertilizers, Farm Feeds, Agricultural Remedies and Stock Remedies Act, 1947 (Act 36 of 1947).

    Consolidated Schedules 06 July 2026, lines 8032 to 8033

  • S4: Trimethoprim

    • except when specifically intended and registered in combination with sulphonamides for the treatment of gastro-enteritis and pneumonia in terms of the provisions of the Fertilizers, Farm Feeds, Agricultural Remedies and Stock Remedies Act, 1947 (Act 36 of 1947).

    Consolidated Schedules 06 July 2026, lines 8287 to 8289

Pharmacological class: Other than antibiotics. (class 20.2)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

Combination product

This product contains more than one active ingredient, so it has no single molecular structure.

SAHPRA documents

SAHPRA has not published a professional information or patient information leaflet for this product.

Background

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Research articles

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