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Lopinavir, ritonavir (Rilovia, Dupirta, Pefrilo, Lopinavir/ritonavir For Mylan)

Lopinavir, ritonavir

Viatris Healthcare (Pty) Ltd

S4

Registration

Applicant
Viatris Healthcare (Pty) Ltd
Registrations
5
Schedule source
Consolidated Schedules 06 July 2026

Variants

ProductStrength and formRegistrationStatusScheduleLeaflets
Rilovia 200/50

EACH TABLET CONTAINS LOPINAVIR 200,0 mg RITONAVIR 50,0 mg

200/5045011145/20.2.8/0111RegisteredS4None
Rilovia

EACH TABLET CONTAINS LOPINAVIR 100,0 mg RITONAVIR 25,0 mg

Not listed45033645/20.2.8/0336RegisteredS4None
Dupirta

EACH SACHET CONTAINS LOPINAVIR 40,0 mg RITONAVIR 10,0 mg

40 mg, 10 mgOral granules55056755/20.2.8/0567Approved 26 September 2023RegisteredS4PIPIL
Pefrilo

EACH SACHET CONTAINS LOPINAVIR 40,0 mg RITONAVIR 10,0 mg

40 mg, 10 mgOral granules550568.56755/20.2.8/0568.567Approved 26 September 2023RegisteredS4PIPIL
Lopinavir/ritonavir 40 mg/10 MG granules for oral suspension mylan

EACH SACHET CONTAINS LOPINAVIR 40,0 mg RITONAVIR 10,0 mg

40 mg/10 mgGranules oral suspension56004656/20.2.8/0046CancelledS4None

Regulatory status

Where S4 sits on the scale

Prescription-only medicine.

Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S4, matched to the Consolidated Schedules by ingredient, confidence medium.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Lopinavir, ritonavir

  • S4: Lopinavir

    Consolidated Schedules 06 July 2026, line 6964

  • S4: Ritonavir

    Consolidated Schedules 06 July 2026, line 7820

Pharmacological class: Antiviral agents. (class 20.2.8)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

Combination product

This product contains more than one active ingredient, so it has no single molecular structure.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

This medication's schedule (S4) has been verified from official SAHPRA documents with 90% confidence.

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Background

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Research articles

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