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zameds

Progesterone

Sold as Utrogestan, Lutiges, Tanilive, Tanilive vaginal, Crinone, Cyclogest

S4
Loading the molecular structure
C21H30O2314.50 g/mol

(8S,9S,10R,13S,14S,17S)-17-Acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

Drag to rotate. Structure from PubChem CID 5994.

Background

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Registration

Applicants
5
Registrations
9
Schedule source
Consolidated Schedules 06 July 2026

Applicants and registrations

ApplicantBrandsDosagesRegistrationsScheduleLeaflets
Medi Challenge (Pty) LtdUtrogestan200 mg290215, A400771S4None
Ferring (Pty) LtdCertificate held by Ferring (Pty) Ltd.Lutiges100 mg451098S4PIPIL
Pharma Dynamics (Pty) LtdCertificate held by Pharma Dynamics (Pty) Ltd.Tanilive, Tanilive vaginal100 mg, 100 or 200 mg, 200 mg570422, 570423, 580036, 580037S4PIPIL
Merck (Pty) LtdCrinone8%A380615S4None
Cipla Medpro (Pty) LtdCyclogest200 mgZ0294S4None

Variants

ProductStrength and formRegistrationStatusScheduleLeaflets
Utrogestan

EACH CAPSULE CONTAINS PROGESTERONE 100 mg

Not listed29021529/21.8.2/0215RegisteredS4None
Lutiges100 mgVaginal tablets.45109845/21.8.2/1098Approved 29 June 2021RegisteredS4PIPIL
Tanilive 100 MG oral capsules

EACH CAPSULE CONTAINS: PROGESTERONE 100,0 mg

100 mgOral capsules57042257/21.8.2/0422RegisteredS4None
Tanilive 200 MG oral capsules

EACH CAPSULE CONTAINS: PROGESTERONE 200,0 mg

200 mgOral capsules57042357/21.8.2/0423RegisteredS4None
Tanilive 100 MG vaginal capsules

Each Capsule contains: Progesterone 100,0 mg

100 or 200 mgSoft gelatin capsule.58003658/21.8.2/0036Approved 17 June 2025RegisteredS4PIPIL
Tanilive 200 MG vaginal capsules

Each Capsule contains: Progesterone 200,0 mg

100 or 200 mgSoft gelatin capsule.58003758/21.8.2/0037Approved 17 June 2025RegisteredS4PIPIL
Crinone 8%

EACH 1,125 g GEL CONTAINS PROGESTERONE 90,0 mg

8%A380615A38/21.8.2/0615RegisteredS4None
Utrogestan 200 MG

EACH CAPSULE CONTAINS PROGESTERONE 100,0 mg

200 mgA400771A40/21.8.2/0771RegisteredS4None
Cyclogest 200 MG

EACH PASSARY CONTAINS PROGESTERONE 200 mg

200 mgZ0294Z/21.8.2/294RegisteredS4None

Regulatory status

Where S4 sits on the scale

Prescription-only medicine.

Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S4, matched to the Consolidated Schedules by ingredient, confidence high.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Progesterone

  • S4: Progesterone

    Consolidated Schedules 06 July 2026, line 7659

Pharmacological class: Progesterones with or without oestrogens. (class 21.8.2)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

Lutiges, Ferring (Pty) Ltd is scheduled S4 in its official SAHPRA documents, read with 90% confidence.

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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